Dysregulation of TFDP1 and of the cell cycle pathway in high-grade glioblastoma multiforme: a bioinformatic analysis
Authors: X. Lu, X.D. Lv, Y.H. Ren, W.D. Yang, Z.B. Li, L. Zhang and X.F. Bai
Despite extensive research, the prognosis of high-grade glioblastoma multiforme (GBM) has improved only slightly because of the limited response to standard treatments. Recent advances (discoveries of molecular biomarkers) provide new opportunities for the treatment of GBM. The aim of the present study was to identify diagnost.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027646
- DOI:
- 10.4238/gmr.15027646
Th17/Treg cell expression in children with primary nephritic syndrome and the effects of ox-LDL on Th17/Treg cells
Authors: Y.Y. Li, S.G. Wei, X. Zhao, Y.Z. Jia, Y.F. Zhang and S.Z. Sun
To investigate the role of T-helper cells/Treg (Th17/Treg) and morbidity factors related to primary nephritic syndrome (PNS) in children, as well as the influence of ox-low density lipoprotein (ox-LDL) on Th17/Treg expression in children with PNS. To clarify the pathogenesis of PNS in children, 50 children with PNS treated in .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027669
- DOI:
- 10.4238/gmr.15027669
Change in heritability estimates due to half-sib family selection in the maize variety Pahari
Authors: M. Noor, D. Shahwar, H. Rahman, H. Ullah, F. Ali, M. Iqbal, I.A. Shah and I. Ullah
This research was carried out at the Agriculture Research Farm, Khyber Pakhtunkhwa Agricultural University, Peshawar, and the Cereal Crops Research Institute, Pirsabak, Nowshera, during 2009 and 2010. Half-sib families (HS) derived from the maize variety Pahari in spring crop seasons 2009 and 2010 were developed at the Cereal Crops Research Institute. All.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.January.16.1
- DOI:
- 10.4238/2013.January.16.1
Population genetic structure of critically endangered salamander (Hynobius amjiensis) in China: recommendations for conservation
Authors: J. Yang, C.S. Chen, S.H. Chen, P. Ding, Z.Y. Fan, Y.W. Lu, L.P. Yu and H.D. Lin
Amji’s salamander (Hynobius amjiensis) is a critically endangered species (IUCN Red List), which is endemic to mainland China. In the present study, five haplotypes were genotyped for the mtDNA cyt b gene in 45 specimens from three populations. Relatively low levels of haplotype diversity (h = 0.524) and nucleotide diver.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027733
- DOI:
- 10.4238/gmr.15027733
Whole-genome duplications contributed to the expansion of cytochrome b5 genes in Paramecium tetraurelia
Authors: K.J. Wu, D. Wang, J. Ding, S.H. Yang and X.H. Zhang
Cytochrome b5 (cyt b5) genes encode ubiquitous electron transport hemoproteins found in animals, plants, fungi, and purple bacteria. However, little is known about their evolutionary history in genomes so far. Here, we conducted an extensive genome-wide survey of cyt b5 genes in 20 representative model species and identified 310 of these genes. Both the a.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.January.9.1
- DOI:
- 10.4238/2013.January.9.1
G�±q gene promoter polymorphisms and rheumatoid arthritis in the Han Chinese population are not associated
Authors: Y. Li, Y. Wang, Y. He, D. Wang, L. Deng, Y. Du and G. Shi
Mice that lose Gαq from their immune system can spontaneously develop inflammatory arthritis. Gαq expression in the peripheral blood lymphocytes of rheumatoid arthritis (RA) patients is significantly decreased in comparison to that in healthy individuals, and reduced Gαq expression is closely correlated with RA disease activity. These in.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.January.4.6
- DOI:
- 10.4238/2013.January.4.6
Cloning and polymorphism analysis of the 2-methyl-6-phytyl-1,4-benzoquinol methyltransferase gene (VTE3) in Arachis hypogaea, A. duranensis, and A. ipa�«nsis
Authors: F.Z. Liu, A.Q. Guo and Y.S. Wan
One of the critical enzymes involved in vitamin E biosynthesis in plants is 2-methyl-6-phytyl-1,4-benzoquinol methyltransferase (MPBQ MT). The full-length VTE3 cDNA (designated rVTE3-1 and -2) encoding MPBQ MT and the full-length DNA of VTE3 (designated gVTE3-1 and -2) were isolated from cultivated peanuts (Arachis hypogaea). The full-length DNA of VTE3 (.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.January.4.5
- DOI:
- 10.4238/2013.January.4.5
Karyotype studies on populations of two Hypochaeris species (H. catharinensis and H. lutea), Asteraceae, endemics to southern Brazil
Authors: F.G. Fiorin, P.M. Ruas, M.A. Ortiz, E. Urtubey, N.I. Matzenbacher and C.F. Ruas
Hypochaeris is an excellent system for studying different modes of chromosome evolution in plants. We carried out a cytogenetic analysis on populations of 2 Hypochaeris species, comprising 10 populations of H. catharinensis and 5 of H. lutea, to assess possible changes on chromosome organization in this interesting genus. Conventional Feulgen staining and.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.January.4.4
- DOI:
- 10.4238/2013.January.4.4
Genetic variations in the Wnt signaling pathway affect lung function in asthma patients
Authors: S.-H. Wang, F. Xu1, H.-X. Dang and L. Yang
Identifying genetic determinants for lung function is important in providing insight into the pathophysiology of asthma. The Wnt signal pathway plays a role in lung development and in asthma pathogenesis. However, whether genetic polymorphisms of Wnt signal pathway are associated with lung function in asthma patients remain unclear. We genotyped 2 single .. Read More»
- Genet. Mol. Res. 12(2):
- 2013.January.4.1
- DOI:
- 10.4238/2013.January.4.1
Effects of autologous SCF- and G-CSF-mobilized bone marrow stem cells on hypoxia-inducible factor-1 in rats with ischemia reperfusion renal injury
Authors: L.Y. Bi,D.A. Zhao,D.S. Yang,J.G. Guo,B. Liang,R.X. Zhang,J.L. Zhao,H.T. Bai and S.J. Li
To explore the mechanism whereby stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF) jointly mobilize bone marrow stem cells (BMSCs) and promote kidney repair, male Sprague-Dawley rats were randomly assigned into 4 groups. In the treatment control group, rats were administered SCF (200 μg· kg-1·day-1) and G-CSF (50 &m.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.27.25
- DOI:
- http://dx.doi.org/10.4238/2015.April.27.25