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Human Genetics   Research Article

Change in heritability estimates due to half-sib family selection in the maize variety Pahari

Authors: M. Noor, D. Shahwar, H. Rahman, H. Ullah, F. Ali, M. Iqbal, I.A. Shah and I. Ullah

This research was carried out at the Agriculture Research Farm, Khyber Pakhtunkhwa Agricultural University, Peshawar, and the Cereal Crops Research Institute, Pirsabak, Nowshera, during 2009 and 2010. Half-sib families (HS) derived from the maize variety Pahari in spring crop seasons 2009 and 2010 were developed at the Cereal Crops Research Institute. All.. Read More»

Genet. Mol. Res. 12(2):
2013.January.16.1
DOI:
10.4238/2013.January.16.1
Animal Genetics   Research Article

Population genetic structure of critically endangered salamander (Hynobius amjiensis) in China: recommendations for conservation

Authors: J. Yang, C.S. Chen, S.H. Chen, P. Ding, Z.Y. Fan, Y.W. Lu, L.P. Yu and H.D. Lin

Amji’s salamander (Hynobius amjiensis) is a critically endangered species (IUCN Red List), which is endemic to mainland China. In the present study, five haplotypes were genotyped for the mtDNA cyt b gene in 45 specimens from three populations. Relatively low levels of haplotype diversity (h = 0.524) and nucleotide diver.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027733
DOI:
10.4238/gmr.15027733
Cytogenomics   Research Article

Whole-genome duplications contributed to the expansion of cytochrome b5 genes in Paramecium tetraurelia

Authors: K.J. Wu, D. Wang, J. Ding, S.H. Yang and X.H. Zhang

Cytochrome b5 (cyt b5) genes encode ubiquitous electron transport hemoproteins found in animals, plants, fungi, and purple bacteria. However, little is known about their evolutionary history in genomes so far. Here, we conducted an extensive genome-wide survey of cyt b5 genes in 20 representative model species and identified 310 of these genes. Both the a.. Read More»

Genet. Mol. Res. 12(2):
2013.January.9.1
DOI:
10.4238/2013.January.9.1
ICBEB   Research Article

G�±q gene promoter polymorphisms and rheumatoid arthritis in the Han Chinese population are not associated

Authors: Y. Li, Y. Wang, Y. He, D. Wang, L. Deng, Y. Du and G. Shi

Mice that lose Gαq from their immune system can spontaneously develop inflammatory arthritis. Gαq expression in the peripheral blood lymphocytes of rheumatoid arthritis (RA) patients is significantly decreased in comparison to that in healthy individuals, and reduced Gαq expression is closely correlated with RA disease activity. These in.. Read More»

Genet. Mol. Res. 12(2):
2013.January.4.6
DOI:
10.4238/2013.January.4.6
Microbial Genetics   Research Article

Cloning and polymorphism analysis of the 2-methyl-6-phytyl-1,4-benzoquinol methyltransferase gene (VTE3) in Arachis hypogaea, A. duranensis, and A. ipa�«nsis

Authors: F.Z. Liu, A.Q. Guo and Y.S. Wan

One of the critical enzymes involved in vitamin E biosynthesis in plants is 2-methyl-6-phytyl-1,4-benzoquinol methyltransferase (MPBQ MT). The full-length VTE3 cDNA (designated rVTE3-1 and -2) encoding MPBQ MT and the full-length DNA of VTE3 (designated gVTE3-1 and -2) were isolated from cultivated peanuts (Arachis hypogaea). The full-length DNA of VTE3 (.. Read More»

Genet. Mol. Res. 12(2):
2013.January.4.5
DOI:
10.4238/2013.January.4.5
Microbial Genetics   Research Article

Karyotype studies on populations of two Hypochaeris species (H. catharinensis and H. lutea), Asteraceae, endemics to southern Brazil

Authors: F.G. Fiorin, P.M. Ruas, M.A. Ortiz, E. Urtubey, N.I. Matzenbacher and C.F. Ruas

Hypochaeris is an excellent system for studying different modes of chromosome evolution in plants. We carried out a cytogenetic analysis on populations of 2 Hypochaeris species, comprising 10 populations of H. catharinensis and 5 of H. lutea, to assess possible changes on chromosome organization in this interesting genus. Conventional Feulgen staining and.. Read More»

Genet. Mol. Res. 12(2):
2013.January.4.4
DOI:
10.4238/2013.January.4.4
Human Genetics   Research Article

Genetic variations in the Wnt signaling pathway affect lung function in asthma patients

Authors: S.-H. Wang, F. Xu1, H.-X. Dang and L. Yang

Identifying genetic determinants for lung function is important in providing insight into the pathophysiology of asthma. The Wnt signal pathway plays a role in lung development and in asthma pathogenesis. However, whether genetic polymorphisms of Wnt signal pathway are associated with lung function in asthma patients remain unclear. We genotyped 2 single .. Read More»

Genet. Mol. Res. 12(2):
2013.January.4.1
DOI:
10.4238/2013.January.4.1
Animal Genetics   Research Article

Effects of autologous SCF- and G-CSF-mobilized bone marrow stem cells on hypoxia-inducible factor-1 in rats with ischemia reperfusion renal injury

Authors: L.Y. Bi,D.A. Zhao,D.S. Yang,J.G. Guo,B. Liang,R.X. Zhang,J.L. Zhao,H.T. Bai and S.J. Li

To explore the mechanism whereby stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF) jointly mobilize bone marrow stem cells (BMSCs) and promote kidney repair, male Sprague-Dawley rats were randomly assigned into 4 groups. In the treatment control group, rats were administered SCF (200 μg· kg-1·day-1) and G-CSF (50 &m.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.27.25
DOI:
http://dx.doi.org/10.4238/2015.April.27.25
Plant Genetics   Research Article

Mating system patterns of natural populations of Pinus koraiensis along its post-glacial colonization route in northeastern China

Authors: X. Sui,F.J. Feng,D. Zhao,M. Xing,X.Y. Sun,S.J. Han and M.H. Li

To understand the genetic mechanisms underlying the endangerment of Pinus koraiensis, we studied the mating system of 49 families of this species in 3 natural populations along its post-glacial colonization route across ~1500 km in northeastern China using the chloroplast simple sequence repeat technique. We analyzed 11 polymorphic loci with clear and rep.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.27.26
DOI:
http://dx.doi.org/10.4238/2015.April.27.26
Human Genetics   Research Article

A novel FBN1 heterozygous mutation identified in a Chinese family with autosomal dominant Marfan syndrome

Authors: Y. Yin1,X.-H. Liu2,X.-H. Li,N. Fan,D.-F. Lei,Y. Wang,S.-P. Cai,X.-M. Zhou,X.-M. Chen and X.-Y. Liu

The purpose of this study was to identify the clinical features and mutations in the fibrillin-1 gene (FBN1) in a large Chinese family with autosomal dominant Marfan syndrome (MFS). Seventeen members from a Chinese family of 4 generations were included in the study. All members underwent complete ophthalmic examination. Molecular genetic analysis was perf.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.27.27
DOI:
http://dx.doi.org/10.4238/2015.April.27.27