Study of the relationship between IL-10 polymorphism and serum lipoprotein levels in Han Chinese individuals
Authors: W.Q. Yang
Previous studies have shown that cytokines can affect serum lipoprotein concentrations. The aim of this study was to examine the association between IL-10 gene polymorphisms and serum lipoprotein levels of Han Chinese individuals. A total of 359 Han Chinese people were enrolled in this investigation. IL-10 -592, -819, and -108.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028016
- DOI:
- 10.4238/gmr.15028016
Isolation and characterization of microsatellite markers for Osmanthus fragrans (Oleaceae) using 454 sequencing technology
Authors: W.J. Yuan, Y. Li, Y.F. Ma, Y.J. Han and F.D. Shang
Osmanthus fragrans (Oleaceae) is an evergreen shrub or small tree that grows in south China. In this study, Roche 454 FLX+ sequencing combined with the magnetic bead enrichment method was used to isolate microsatellite markers from the genome of O. fragrans. A total of 1471 microsatellites that contained enough flanking sequences for primer pair design we.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.15
- DOI:
- 10.4238/2015.December.16.15
Single-nucleotide polymorphisms in dopamine receptor D1 are associated with heroin dependence but not impulsive behavior
Authors: J.H. Liu,H.J. Zhong,J. Dang,L. Peng and Y.S. Zhu
Previous studies suggested that dopamine receptors may be associated with drug dependence and impulsive behavior. In this study, we examined whether dopamine receptor D1 (DRD1) is associated with heroin dependence and the impulsive behavior in patients with heroin dependence. The participants included 367 patients with heroin dependence and 372 healthy co.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.27.19
- DOI:
- http://dx.doi.org/10.4238/2015.April.27.19
Identification and phylogenetic analysis of a sheep pox virus isolated from the Ningxia Hui Autonomous Region of China
Authors: X.L. Zhu, F. Yang, H.X. Li, Y.X. Dou, X.L. Meng, H. Li, X.N. Luo and X.P. Cai
An outbreak of sheep pox was investigated in the Ningxia Hui Autonomous Region in China. Through immunofluorescence testing, isolated viruses, polymerase chain reaction identification, and electron microscopic examination, the isolated strain was identified as a sheep pox virus. The virus was identified through sequence and phylogenetic analysis of the P3.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.14.7
- DOI:
- 10.4238/2013.May.14.7
Association between NOS3 genetic variants and coronary artery disease in the Han population
Authors: G.L. Zhao, Q.J. Li and H.Y. Lu
The enzyme endothelial nitric oxide synthase (NOS3) is an important mediator of atherosclerotic disease and is associated with coronary artery disease (CAD). There is growing evidence that polymorphisms in NOS3 influence the progression of CAD; however, there is also a controversy regarding the association of polymorphisms in .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028044
- DOI:
- 10.4238/gmr.15028044
Study of genetic variation of eggplant cultivars by using RAPD-PCR molecular markers and the relationship with Phomopsis blight disease reaction
Authors: H.A. Asad, M.B. Meah, S.N. Begum, M.I. Khalil, M.Y. Rafii and M.A. Latif
Disease susceptibility and genetic variability in 10 eggplant genotypes were studied after inoculating Phomopsis vexans under confined field conditions. Random amplified polymorphic DNA (RAPD) markers were used to assess genetic variation and relationships among eggplant genotypes. The disease index of leaves ranged 0.208-13.79%, while fruit infection ran.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.1
- DOI:
- 10.4238/2015.December.16.1
Lack of association between the methylenetetrahydropholate reductase gene A1298C polymorphism and neural tube defects in a Turkish study group
Authors: S.H. Yildiz, M. Ozdemir Erdogan, M. Solak, O. Eser, E.S. Ar�±kan Terzi, B. Eser, V. Kocaba�� and A. Aslan
The etiology underlying neural tube defects (NTDs) is not fully understood and is believed to involve a complex milieu of genetic and environmental factors. The A1298C polymorphism in the methylenetetrahydropholate reductase gene (MTHFR) has been associated with mild risk for NTDs. In this study, the genotype distribution of t.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028051
- DOI:
- 10.4238/gmr.15028051
R337H mutation of the TP53 gene as a clinical marker in cancer patients: a systematic review of literature
Authors: L.M. Borges and F.M. Ayres
The germline R337H mutation of the TP53 gene has been associated with the development of many tumor types. This systematic review of literature investigated the association between the R337H mutation and the patients’ family history and its predictive and prognostic value in cancer. Data were collected from articles archived in the PubMed, LILACS, M.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.4
- DOI:
- 10.4238/2015.December.16.4
Interaction between ALOX5AP-SG13S114A/T and COX-2-765G/C increases susceptibility to cerebral infarction in a Chinese population
Authors: X.Y. Yi, Q. Zhou, J. Lin, L.F. Chi and W.Z. Chi
We made a case-control study to investigate a possible association between ALOX5AP-SG13S114A/T, COX-2-765G/C, and COX-1-50C/T polymorphisms with cerebral infarction in a Chinese population. A total of 411 cases with cerebral infarction were included; 411 controls matched for age, gender, and risk factors were also selected. The ALOX5AP-SG13S114A/T (rs1050.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.14.6
- DOI:
- 10.4238/2013.May.14.6
Cytogenetic description of Ancistrus abilhoai (Siluriformes: Loricariidae) from Igua�§u River basin, southern Brazil
Authors: M.O. Ribeiro,R.B. Noleto,C.A. Lorscheider,F.E. Porto,A.C. Prizon,C.H. Zawadzki,L.C. Oliveira and A.L.B. Portela Castro
The Iguaçu River basin is a tributary to the upper Paraná River in southern Brazil, and is considered an important aquatic ecoregion that, although having few species of fish, 51-71% of these are apparently endemic. Ancistrus abilhoai is one of three recently described species for this basin and is currently considered endemic to the basin. .. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.27.20
- DOI:
- http://dx.doi.org/10.4238/2015.April.27.20