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Plant Genetics   Research Article

Molecular diversity analysis of eggplant (Solanum melongena) genetic resources

Authors: Z. Ali, Z.L. Xu, D.Y. Zhang, X.L. He, S. Bahadur and J.X. Yi

Eggplant (Solanum melongena), a vegetable that is cultivated worldwide, is of considerable importance to agriculture in China. We analyzed the diversity of this plant using inter-simple sequence repeat (ISSR) and RAPD procedures to subdivide 143 Chinese-cultivated eggplants based on coefficient of parentage, genetic diversity .. Read More»

Genet. Mol. Res. 10(2):
vol10-2gmr1279
DOI:
10.4238/vol10-2gmr1279
Cytogenomics   Research Article

Serotonin receptor 2C gene polymorphism associated with post-stroke depression in Chinese patients

Authors: W.K. Tang, N. Tang, C.D. Liao, H.J. Liang, V.C.T. Mok, G.S. Ungvari and K.S. Wong

The serotonin receptor 2C (HTR2C) gene has been shown to play a pivotal role in major depression. We examined the association between post-stroke depression (PSD) and polymorphism in HTR2C. A cohort of 223 patients with acute lacunar stroke admitted to the stroke unit of a university-affiliated regional hospital in Hong Kong was recruited. Three months af.. Read More»

Genet. Mol. Res. 12(2):
2013.May.13.8
DOI:
10.4238/2013.May.13.8
Plant Genetics   Research Article

Effect of Fimbristylis ovata on receptor for advanced glycation end-products,proinflammatory cytokines, and cell adhesion molecule level and gene expression in U937 and bEnd.3 cell lines

Authors: S. Sukjamnong and R. Santiyanont

Fimbristylis ovata has been long used as a traditional medicine for chronic inflammatory diseases; however, there are no data regarding its anti-inflammatory properties. In this study, we investigated the effects of F. ovata extracts on the secretion of pro-inflammatory cytokines, cell adhesion molecule, and receptor for advanced glycation end-products (R.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.27.13
DOI:
http://dx.doi.org/10.4238/2015.April.27.13
Human Genetics   Research Article

Association between ERCC5 gene polymorphisms and gastric cancer risk in a Chinese population

Authors: R.J. Li, M. Li, G.J. Liu, Y.W. Guo, H. Bai, P. Xiao and J.Z. Mei

We conducted a hospital-based case-control study to investigate the association between 3 common SNPs in the ERCC5 gene (rs1047768, rs751402, and rs17655) and the risk of developing gastric cancer. Between January 2013 and December 2014, samples were collected from 216 gastric cancer patients and 216 control subjects. ERCC5 rs1047768, rs751402, and rs1765.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017510
DOI:
10.4238/gmr.15017510
Plant Genetics   Research Article

Elucidation of thermotolerance diversity in cotton (Gossypium hirsutum L.) using physio-molecular approaches

Authors: R.M. Rana, S.H. Khan, Z. Ali, A.I. Khan and I.A. Khan

Cotton (Gossypium hirsutum) is an important cash crop, but high temperature during its growing season is one of the major factors that limit its productivity. This problem compels plant breeders to breed for heat tolerance, which can help to overcome this challenge. It is very important to make a comprehensive screening of hea.. Read More»

Genet. Mol. Res. 10(2):
vol10-2gmr1180
DOI:
10.4238/vol10-2gmr1180
Cytogenomics   Research Article

A phytotoxin Solanapyrone-A downregulates calcium-dependent protein kinase activity in potato

Authors: A. Hassan, N. Hatsugai and M.M. Shah

We previously demonstrated that alternaric acid, a host-specific toxin produced by the plant pathogenic fungus Alternaria solani, in the presence of Ca2+ and Mg2+, stimulated in vitro phosphorylation of His-tagged calcium-dependent protein kinase 2 from potato cultivar Rishiri (RiCDPK2). Herein, we report that Solanapyrone-A (SpA), a non-host-specific tox.. Read More»

Genet. Mol. Res. 12(2):
2013.May.13.7
DOI:
10.4238/2013.May.13.7
Human Genetics   Original Articles

Phenotypic expression of homozygous hemoglobin S in relation to �²-globin haplotypes, glutathione S-transferase polymorphisms and detoxification enzymes

Authors: D.G.H. Silva

Sickle cell anemia (SCA) shows a pathophysiology that involves multiple changes in sickle cell erythrocytes, vaso-occlusive episodes, hemolysis, activation of inflammatory mediators, endothelial cell dysfunction, and oxidative stress. These events complicate treatment and culminate in the development of manifestations such as .. Read More»

Genet. Mol. Res. 10(2):
vol10-2ta036
DOI:
10.4238/vol10-2ta036
Plant Genetics   Research Article

Identification of differentially expressed genes in a pistillody common wheat mutant using an annealing control primer system

Authors: M.L. Liao,Z.S. Peng,Z.J. Yang,S.H. Wei and P. Martinek

HTS-1 is a new kind of pistillody wheat. All or parts of its stamen are transformed into pistils or pistil-like structures, and it has more seed sets per floret than normal wheat under normal cultivation conditions. To investigate the expression divergence in this mutant, an annealing control primer system was used to identify differentially expressed gen.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.27.14
DOI:
http://dx.doi.org/10.4238/2015.April.27.14
Human Genetics   Research Article

Evaluation of alternative schemes for recording body weights in meat-type quails by using random regression

Authors: L.P. Silva, J.C. Ribeiro, C.D.S. Leite, M.F. Sousa, C.M. Bonaf�©, G.C. Caetano, A.C. Crispim and R.A. Torres

Data from 8759 meat-type quails from the UFV1 strain and 9128 from the UFV2 strain were used to assess the possibility of reducing the number of body weight records in genetic evaluations. The evaluated animals were weighed weekly since hatching to the 6th week of life, with up to 7 records of body weight for each bird. The data were evaluated by random r.. Read More»

Genet. Mol. Res. 12(2):
Medical Genetics   Research Article

Association of the interleukin-10 gene -1082A/G genetic polymorphism with risk of ischemic stroke in a Chinese population

Authors: W.Z. Li, C.Y. Gao, W.L. He and H.M. Zhang

We investigated the possible association between two single nucleotide polymorphisms of IL10 (-1082A/G and -592C/A) and susceptibility to ischemic stroke. In total, 335 patients with proven ischemic stroke and 335 control subjects were recruited from Xinxiang Central Hospital between March 2013 and May 2015. The IL10 -1082A/G and -529C/A polymorphisms wer.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017541
DOI:
10.4238/gmr.15017541