Effect of temperature on endogenous hormone levels and opposite phyllotaxy in maize leaf primordial
Authors: H. Ye, G.M. Han, Q. Ma, Y.Q. Tan, H.Y. Jiang, S.W. Zhu and B.J. Cheng
Newly identified maize (Zea mays) mutants with opposite leaf phyllotaxy are important in the study of the maize crop. Previous studies have revealed the developmental mechanism of opposite phyllotaxy on the physiological, cellular, and molecular levels. However, there have been few reports regarding the effects of changes in endogenous hormone levels in m.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.2
- DOI:
- 10.4238/2015.December.16.2
Additional chromosomal abnormalities in core-binding factor acute myeloid leukemia
Authors: H.H. Hsiao, Y.C. Liu, H.C. Wang, Y.F. Tsai, C.H. Wu, S.F. Cho, J.F. Hsu, C.T. Huang, S.Y. Hsiao, C.P. Lee, C.S. Chang, S.F. Lin and T.C. Liu
Despite sharing a similar genetic abnormality, patients with core binding factor acute myeloid leukemia (CBF-AML), which is characterized by the presence of t(8;21) or inv(16)/t(16;16), show heterogeneous survival. Other molecular or cytogenetic factors are supposed to have an impact on the prognosis. We enrolled 24 CBF-AML patients to determine the impac.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.3
- DOI:
- 10.4238/2015.December.16.3
Tiaogan Qingxin Granule treatment increases myocardial connexin 43 expression in a rat model of arrhythmia
Authors: J.H. Yao, C.H. Qu, L. Ma and X.Z. Chang
Myocardial ischemia-induced arrhythmia, especially ventricular arrhythmia, is the main reason for sudden cardiac death. Therefore, ischemic ventricular arrhythmia-targeted treatments are urgently needed. The mechanism of Tiaogan Qingxin Granule in premature ventricular beat (PVB) treatment was explored in arrhythmic rats pretr.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027934
- DOI:
- 10.4238/gmr.15027934
In vitro genotoxicity assessment of caffeic, cinnamic and ferulic acids
Authors: E.L. Maistro, J.P.F. Angeli, S.F. Andrade and M.S. Mantovani
Phenols are a large and diverse class of compounds, many of which occur naturally in a variety of food plants; they exhibit a wide range of biological effects, including antibacterial, anti-inflammatory, antiallergic, hepatoprotective, antithrombotic, antiviral, anticarcinogenic, and vasodilatory actions. We examined the genotoxic and clastogenic potentia.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1278
- DOI:
- 10.4238/vol10-2gmr1278
Lactic acid bacteria protect human intestinal epithelial cells from Staphylococcus aureus and Pseudomonas aeruginosa infections
Authors: S. Affhan, W. Dachang, Y. Xin and D. Shang
Staphylococcus aureus and Pseudomonas aeruginosa are opportunistic pathogens that cause nosocomial and food-borne infections. They promote intestinal diseases. Gastrointestinal colonization by S. aureus and P. aeruginosa has rarely been researched. These organisms spread to extra gastrointestinal niches, resulting in increasingly progressive infections. L.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.5
- DOI:
- 10.4238/2015.December.16.5
Effects of the balance between type 1 and type 2 T helper cells on ovarian cancer
Authors: C.J. Hao, J. Li, P. Liu, X.L. Li, Y.Q. Hu, J.C. Sun and Y. Wei
The balance between type 1 and type 2 T helper cells (the Th1-Th2 balance) is closely correlated with cancer, but the correlation in ovarian cancer remains unconfirmed. We investigated the Th1-Th2 balance for the diagnosis, treatment, and prognostic evaluation of ovarian cancer. Fifty healthy subjects and 50 ovarian cancer pat.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027936
- DOI:
- 10.4238/gmr.15027936
Development of novel microsatellite markers for conservation genetic studies of Vulpes vulpes (Canidae) by using next-generation sequencing method
Authors: J.-N. Yu,C.-U. Chung,K.H. Oh,B.-K. Lee and C.E. Lim
The red fox, Vulpes vulpes (Canidae), is the most widely distributed terrestrial carnivore worldwide, but this species is classified as endangered in Korea. In this study, we developed 25 polymorphic microsatellite markers that included 3-13 (mean = 6.32) alleles per locus using 22 red fox individuals. The most polymorphic locus was FR(59)TG (13 alleles) .. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.27.12
- DOI:
- http://dx.doi.org/10.4238/2015.April.27.12
Matrix metalloproteinase 9 -1562C/T polymorphism increased protein levels in patients with colorectal cancer in a sample from southeastern Brazil
Authors: C.R. Hoelzle, K.C.S.F. Magalh�£es, S.S. Carvalho, G.A. Santos, I.M. Maia, M.C.P.S. Sousa, J.S. Andrade-Filho, G.M.G. Cruz and R.T. Sim�µes
We examined whether the allelic and/or genotypic profile of locus -1562C/T of the matrix metalloproteinase (MMP-9) gene influences the protein expression levels of MMP-9 in patients with colorectal cancer (CRC) compared with controls. A total of 104 patients with CRC and 84 controls were evaluated. Peripheral blood was collected from both groups and DNA e.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017478
- DOI:
- 10.4238/gmr.15017478
Expression levels of survivin, Bcl-2, and KAI1 proteins in cervical cancer and their correlation with metastasis
Authors: X.L. Zhou and M. Wang
Cervical cancer is associated with abnormal expression of multiple genes. Survivin and Bcl-2 proteins are apoptosis inhibitors. The tumor suppressor gene CD82, which encodes the protein KAI1, is downregulated in cervical cancer, and is associated with differentiation degree. We investigated the expression levels of three proteins and their correlation wit.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.16.6
- DOI:
- 10.4238/2015.December.16.6
Cellular responses induced in vitro by iron (Fe) in a central nervous system cell line (U343MGa)
Authors: D.D.F.A. Alc�¢ntara, H.F. Ribeiro, L.A. Matos, J.M.C. Sousa, R.R. Burbano and M.O. Bahia
Iron is the most important metallic chemical element on Earth. Poisoning caused by excessive iron in humans has been associated with pulmonary diseases including neoplasms caused by inhalation of iron oxides. The involvement of iron in neurodegenerative processes has already been described. DNA alterations are induced by iron and other chemical compounds .. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.13.9
- DOI:
- 10.4238/2013.May.13.9