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Human Genetics   Research Article

Promoter analysis of bovine cardiomyopathy-associated protein 1 gene

Authors: G.N. Sui, Z.W. Liu, T. Wang, X. Li, X.B. Ding, X.F. Liu and H. Guo

The CMYA1 (cardiomyopathy-associated protein 1) is an actin-binding protein that plays a vital role in cardiac morphogenesis. CMYA1 is expressed specifically in the myocardial and skeletal muscle and is up-regulated in injured muscle. We therefore speculated that the bovine CMYA1 promoter might be muscle-specific. In this stud.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027675
DOI:
10.4238/gmr.15027675
Human Genetics   Research Article

Serum levels of PSA, ALP, ICTP, and BSP in prostate cancer patients and the significance of ROC curve in the diagnosis of prostate cancer bone metastases

Authors: R.J. Wei, T.Y. Li, X.C. Yang, N. Jia, X.L. Yang and H.B. Song

Bone metastasis is a common complication in prostate cancer patients that can cause bone pain and pathological fracture. This study tested serum levels of prostate specific antigen (PSA), alkaline phosphatase (ALP), bone sialoprotein (BSP), collagen type I pyridine crosslinking peptide (ICTP) in prostate cancer patients and th.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027707
DOI:
10.4238/gmr.15027707
Human Genetics   Research Article

Immunohistochemical subtypes of diffuse large B-cell lymphoma in the head and neck region

Authors: J.M. Li,J. Hou,L. Li and Y. Wang

The objectives of this study were to detect immunohistochemical subtypes of diffuse large B-cell lymphoma (DLBCL) of the head and neck, to compare the Hans, Choi, and Tally algorithms and to examine the significance of protein expression in these algorithms. This study included 103 DLBCL patients at Sichuan Cancer Hospital between May 2010 and October 201.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.27.3
DOI:
http://dx.doi.org/10.4238/2015.April.27.3
Human Genetics   Research Article

Effect of GSTM1, GSTT1, and GSTP1 IIe105Val polymorphisms on susceptiblity to gestational diabetes mellitus

Authors: Y.H. Qiu, Y.L. Xu and W.H. Zhang

We investigate the role of the GSTM1, GSTT1, and GSTP1 IIe105Val genetic polymorphisms in the susceptibility to gestational diabetes mellitus. A total of 223 pregnant women with gestational diabetes mellitus and 265 healthy pregnant women were examined at The Second Affiliated Hospital of Shaanxi University of Chinese Medicine.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027711
DOI:
10.4238/gmr.15027711
Plant Genetics   Research Article

Selfing rate estimation in sugarcane under unfavorable natural conditions of crossing by using microsatellite markers

Authors: M.L.G. Melloni , M.S. Scarpari, L.R. Pinto, D. Perecin, M.A. Xavier and M.G.A. Landell

The self-fertilization or selfing rate estimation using microsatellite markers and its impact on survival and selection rate were evaluated in families derived from polycrosses that involved parents that were widely used in sugarcane breeding in Brazil. These factors were evaluated under unfavorable natural conditions of flowe.. Read More»

Genet. Mol. Res. 13(1):
2014.March.31.8
DOI:
10.4238/2014.March.31.8
Plant Genetics   Research Article

Effects of p-chlorophenoxyisobutyric acid, arabinogalactan, and activated charcoal on microspore embryogenesis in kale

Authors: R.Q. Niu,Y. Zhang,Y. Tong,Z.Y. Liu,Y.H. Wang and H. Feng

To improve embryogenesis in microspore cultures of kale (Brassica oleracea L. var. acephala DC.), 6-benzylaminopurine (6-BA), naphthaleneacetic acid (NAA), arabinogalactan (AG), p-chlorophenoxyisobutyric acid (PCIB), and activated charcoal (AC) were added to the medium using four varieties of kale. The results showed that the addition of AG (0.1-0.2 g/L),.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.27.4
DOI:
http://dx.doi.org/10.4238/2015.April.27.4
Human Genetics   Research Article

Mild hypothermia attenuates post-resuscitation brain injury through a V-ATPase mechanism in a rat model of cardiac arrest

Authors: J.C. Zhang, W. Lu, X.M. Xie, H. Pan, Z.Q. Wu and G.T. Yang

Although therapeutic hypothermia is an effective treatment for post-resuscitation brain injury after cardiac arrest (CA), the underlying mechanism remains unclear. Vacuolar H+-ATPase (V-ATPase) plays a key role in cellular adaption to a hypoxic environment. This study sought to evaluate the effect of mild hypothermia on V-ATPa.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027729
DOI:
10.4238/gmr.15027729
Animal Genetics   Research Article

Selected representative microsatellite loci for genetic monitoring and population structure analysis of miniature swine

Authors: C. Wang,L.L. Xu,Y.H. Wu,X.Y. Du,X.Y. Huo,J. Gao,Z.K. Li,Y.C. Li and Z.W. Chen

To optimize the combination of microsatellite loci for genetic control of outbred swine stocks, 32 of 100 loci distributed among almost all chromosomes (except 12) were screened out by 1.5% agarose, 8% polyacrylamide gel and capillary electrophoresis scanning among 3 miniature swine outbred stocks, namely Bama (BM), Guizhou (GZ) and Tibeta (TB). The mean .. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.27.5
DOI:
http://dx.doi.org/10.4238/2015.April.27.5
Human Genetics   Research Article

Comparison of two methods for RNA extraction from the nucleus pulposus of intervertebral discs

Authors: M.F. Gan, H.L. Yang, J.L. Qian, C.S. Wu, C.X. Yuan, X.F. Li and J. Zou

RNA extraction from the nucleus pulposus of intervertebral discs has been extensively used in orthopedic studies. We compared two methods for extracting RNA from the nucleus pulposus: liquid nitrogen grinding and enzyme digestion. The RNA was detected by agarose gel electrophoresis, and the purity was evaluated by absorbance r.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027738
DOI:
10.4238/gmr.15027738
Microbial Genetics   Research Article

An SduI polymorphism at intron 20 of the Chinese Holstein cow STAT4 gene and its effect on milk performance traits

Authors: X.M. Song, L. Zhang, J.F. Jiang, F.X. Shi and Y.Q. Jiang

The signal transducer and activator of transcription (STAT) genes are responsive to a wide range of cytokines, growth factors, and hormones, and thus control important biological processes. In humans, STAT4 mutations have been identified as genetic markers for rheumatoid arthritis, systemic lupus erythematosus, and primary Sjögren’s syndrome, w.. Read More»

Genet. Mol. Res. 12(2):
2013.May.13.13
DOI:
10.4238/2013.May.13.13