Molecular characterization of carbapenemase genes in Acinetobacter baumannii in China
Authors: F. Fang, S. Wang, Y.X. Dang, X. Wang and G.Q. Yu
Acinetobacter baumannii is an aerobic non-motile Gram-negative coccobacillus, and it is one of the most important nosocomial pathogens worldwide. The aim of this study was to determine the molecular epidemiology of the outbreak strains. Between March 2011 and March 2014, a total of 205 strains of A. baumannii were isolated from patients at the Nanyang Cit.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017432
- DOI:
- 10.4238/gmr.15017432
Molecular cloning of the perilipin gene and its association with carcass and fat traits in Chinese ducks
Authors: H.L. Zhang, H.J. Fan, X.L. Liu, Y. Wu and S.S. Hou
The perilipin (PLIN) gene is a candidate gene of carcass and fat traits in ducks. In order to study the molecular character of the PLIN gene and its function in different breeds of Chinese ducks, samples were obtained from the Chinese Academy of Agricultural Sciences Research Center for Birds, including 95 Peking ducks of the Z2 series, 91 Peking ducks of.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.13.12
- DOI:
- 10.4238/2013.May.13.12
CYFRA21-1 levels could be a biomarker for bladder cancer: a meta-analysis
Authors: L.I. Kuang,W.J. Song,H.M. Qing,S. Yan and F.L. Song
The proteolytic region of cytokeratin-19, referred to as CYFRA21-1, is a soluble molecule present in the serum and other body fluids, and is considered a tumor marker in several neoplastic diseases. To examine whether urinary or serum samples containing CYFRA21-1 can be used as biomarkers for bladder cancer, we conducted a comprehensive meta-analysis of 3.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.27.6
- DOI:
- http://dx.doi.org/10.4238/2015.April.27.6
Text-mining network analysis of the response to osmotic stimuli in the intervertebral disc
Authors: X. Xu, L. Liu and Q.Y. Lu
Intervertebral disc cells experience a broad range of physical stimuli under physiologic conditions, including alterations in their osmotic environment. The purpose of this study was to construct a text-mining network of the genes induced during the response to osmotic stimuli in the intervertebral disc. We obtained a gene expression profile of human inte.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.13.11
- DOI:
- 10.4238/2013.May.13.11
HuGE systematic review and meta-analysis demonstrate association of CASP-3 and CASP-7 genetic polymorphisms with cancer risk
Authors: S. Yan, Y.Z. Li, X.W. Zhu, C.L. Liu, P. Wang and Y.L. Liu
Genetic variations in the caspase genes CASP-3 and CASP-7 are known to be involved in apoptosis, cytokine maturation, cell growth and differentiation. Polymorphisms of CASP-3 and CASP-7 genes have been increasingly recognized as important regulators in the development of cancer. However, whether there is a specific association is still controversial. Ther.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.13.10
- DOI:
- 10.4238/2013.May.13.10
Co-culture of annulus fibrosus cells and bone marrow mesenchymal stem cells
Authors: Y. Xu,X.J. Zhang,L. Fang and T.B. Zhao
To investigate the effect on cell proliferation and extracellular matrix expression of annulus fibrosus (AF) cells when co-cultured with bone marrow mesenchymal stem cells (BMSCs). Primary isolated rabbit BMSCs and AF cells were cultured and harvested cells were placed into a 15-mL centrifugal tube co-culture system in a ratio of 2:1 (A group), 1:1 (B gro.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.27.7
- DOI:
- http://dx.doi.org/10.4238/2015.April.27.7
CpG island evolution in the mammalian DHRS4 gene cluster and its role in the regulation of gene transcription
Authors: Z. Su, G. Liu, X. Song, B. Liang, X. Chang and D. Huang
The dehydrogenase/reductase (SDR family) member 4 (DHRS4) gene is copied during mammalian evolution; therefore, while only one DHRS4 gene is expressed in the mouse genome, the gene cluster consists of two (DHRS4 and DHRS4L1) and three (DHRS4, DHRS4L2, and DHRS4L1) copies in chimpanzees and humans, respectively. In this study, .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027752
- DOI:
- 10.4238/gmr.15027752
IL-17 rs2275913 genetic variation contributes to the development of gastric cancer in a Chinese population
Authors: B.L. Xu, Y.T. Li, S.X. Dong, J. Qi, H.M. Feng, L. Zi and D.Y. Yang
The purpose of this hospital-based case-control study was to assess whether the interleukin (IL)-17 rs2275913 genetic variation can influence susceptibility to gastric cancer. Samples from a total of 202 gastric cancer patients and 237 controls were collected from the Linyi People’s Hospital between March 2013 and March .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027756
- DOI:
- 10.4238/gmr.15027756
Effect and mechanism of different ways of transplanting bone marrow mesenchymal stem cells in cardiopulmonary resuscitation in rats
Authors: L.L. Zhou, J.K. Liang, Q.M. Lin and Z.T. Huang
The effect and mechanism of different ways of transplanting bone marrow mesenchymal stem cells (MSCs) were explored for treating cardiopulmonary resuscitation in a rat model. Rats were divided into the cardiopulmonary resuscitation group (Group Con), the stereotactic lateral ventricle transplantation group (Group LV), the inte.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.29.7
- DOI:
- 10.4238/2014.September.29.7
High-resolution color doppler ultrasound examination and related risk factor analysis of lower extremity vasculopathy in type 2 diabetes patients
Authors: J. Xu,G. Wang,D. Fu,N. Su,L. Wang,F. Gao and N. Guo
This study aims to investigate the value of high-resolution color Doppler ultrasonography (HR-CDU) in the evaluation of lower-extremity vasculopathy (LEV) and its related risk factors in type 2 diabetes mellitus (T2DM) patients. Two hundred forty T2DM patients were selected, who underwent lower-extremity arterial HR-CDU. The patients were divided into the.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.27.8
- DOI:
- http://dx.doi.org/10.4238/2015.April.27.8