Dietary glycerol for quail: association between productive performance and COX III mRNA expression
Authors: S.C.C. Silva, E. Gasparino, E. Batista, F. Tanamati, A.P.D. Vesco, B. Lala and D.P. de Oliveira
This study was carry out to evaluate mRNA expression of mitochondrial cytochrome c oxidase III in the Pectoralis superficialis muscle of 28-day-old quails fed diets containing 0, 8, and 12% glycerol. Total RNA was extracted (N = 10) and cDNA was amplified using specifics primers for qRT-PCR. Feed efficiency and feed intake wer.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027435
- DOI:
- 10.4238/gmr.15027435
Cloning and sequence analysis of the LOC339524 gene in Sprague-Dawley rats
Authors: Z.H. Long, H. Li, F. Chen and L.Y. Zou
We cloned the LOC339524 gene in Sprague-Dawley (SD) rats and analyzed the structure and function of the protein encoded by it. Based on the known human LOC339524 gene sequences, the full-length coding sequence of the LOC339524 gene in SD rats was cloned and amplified by the polymerase chain reaction using the complementary DNA of SD rats as a template. Bi.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.11.4
- DOI:
- 10.4238/2015.December.11.4
Estimation of genetic parameters for growth traits in a breeding program for rainbow trout (Oncorhynchus mykiss) in China
Authors: G. Hu, W. Gu, Q.L. Bai and B.Q. Wang
Genetic parameters and breeding values for growth traits were estimated in the first and, currently, the only family selective breeding program for rainbow trout (Oncorhynchus mykiss) in China. Genetic and phenotypic data were collected for growth traits from 75 full-sibling families with a 2-generation pedigree. Genetic parameters and breeding values for.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.26.7
- DOI:
- 10.4238/2013.April.26.7
Detection of serum antinuclear antibodies in lymphoma patients
Authors: H.Y. Zou, X. Gu, W.Z. Yu, Z. Wang and M. Jiao
We investigated the presence of serum antinuclear antibodies (ANAs) and autoantibodies and their relationship with serum prognostic indicators in lymphoma patients. The study population comprised 127 patients diagnosed with lymphoma and 138 healthy control subjects. The blood samples of the participants were assayed for ANAs by immunofluorescence, and aut.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.11.1
- DOI:
- 10.4238/2015.December.11.1
Decreased microRNA-198 expression and its prognostic significance in human glioma
Authors: H.B. Man, W.P. Bi and H.H. Man
Previous evidence has shown the association of aberrant miR-198 expression with tumorigenesis and progression of many human malignancies. However, its involvement in human glioma is still unclear. Therefore, the aim of the current study was to investigate the expression and function of miR-198 in human gliomas. Using real-time.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027656
- DOI:
- 10.4238/gmr.15027656
Effect of CYP1A1 and GSTM1 genetic polymorphisms on bone tumor susceptibility
Authors: L. Li, J.G. Li, C.Y. Liu and Y.J. Ding
Tumor gene polymorphisms are often associated with individual susceptibility to genetic diseases. Cytochrome P4501A1 (CYP1A1) and glutathione S-transferase mu 1 (GSTM1) gene polymorphisms are closely related to the susceptibility of the body to chemical carcinogens in the environment. Therefore, we explored the relationship between CYP1A1 and GSTM1 gene p.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.11.7
- DOI:
- 10.4238/2015.December.11.7
ATP-dependent chromatin remodeling and histone acetyltransferases in 5-FU cytotoxicity in Saccharomyces cerevisiae
Authors: R. Matuo, F.G. Sousa, D. Bonatto, A.A. Mielniczki-Pereira, J. Saffi, D.G. Soares, A.E. Escargueil, A.K. Larsen and J.A.P. Henriques
Chromatin is thought to modulate access of repair proteins to DNA lesions, and may be altered by chromatin remodelers to facilitate repair. We investigated the participation of chromatin remodelers and DNA repair in 5-fluorouracil (5-FU) cytotoxicity in Saccharomyces cerevisiae. 5-FU is an antineoplastic drug commonly used in clinical settings. Among the .. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.26.6
- DOI:
- 10.4238/2013.April.26.6
Detection and characterization of carbendazim resistance in Sclerotinia sclerotiorum isolates from oilseed rape in Anhui Province of China
Authors: D. Xu, Y. Pan, H. Zhang, X. Li, Y. Dai, S. Cao and Z. Gao
Stem rot caused by Sclerotinia sclerotiorum is a devastating disease of oilseed rape (Brassica napus) in Anhui Province of China. The fungicide carbendazim (methyl benzimidazole-2-yl carbamate; MBC) has been used to control this fungal disease since the 1980s. In the present study, 74 isolates of S. sclerotiorum from 13 regions of Anhui were collected, an.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.11.10
- DOI:
- 10.4238/2015.December.11.10
Comparative analysis of MIR168 promoters in three plant species
Authors: D. Qu, F. Yan M.A. Li, C. Varotto and Z.Y. Zhao
MicroRNAs (miRNAs) play important roles in the regulation of gene expression by post-transcriptionally targeting mRNAs for cleavage or translational repression. miR168 is a key miRNA because it regulates the expression of the slicer protein ARGONAUTE1 (AGO1), which catalyzes mRNA cleavage. Interestingly, plant miR168s are high.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027684
- DOI:
- 10.4238/gmr.15027684
Result and pedigree analysis of spontaneously abortion villus chromosome detecting by FISH
Authors: N. An, L.-L. Li, X.-Y. Zhang, W.-T. Sun, M.-H. Liu and R.-Z. Liu
The aim of this study was to evaluate the relationship between fetal karyotype and parental chromosomal abnormalities, and to provide a basis for clinical diagnosis and therapy in Northeast China. A total of 144 spontaneously aborted fetuses were analyzed by FISH to test for chromosome number and to recall couples for peripheral blood karyotype analysis. .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.11.13
- DOI:
- 10.4238/2015.December.11.13