Screening for key genes associated with invasive ductal carcinoma of the breast via microarray data analysis
Authors: J.L. Huan, X. Gao, L. Xing, X.J. Qin, H.X. Qian, Q. Zhou and L. Zhu
The aim of this study was to identify key genes related to invasive ductal carcinoma (IDC) of the breast by analyzing gene expression data with bioinformatic tools. Microarray data set GSE31138 was downloaded from Gene Expression Omnibus, including 3 breast cancer tissue samples and 3 normal controls. Differentially expressed .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.29.5
- DOI:
- 10.4238/2014.September.29.5
Cellulolytic activity and structure of symbiotic bacteria in locust guts
Authors: L.-J. Su, H. Liu, Y. Li, H.-F. Zhang, M. Chen, X.-H. Gao, F.-Q. Wang and A.-D. Song
Locusts are able to digest the cellulose of Gramineae plants, resulting in their being considered as major crop pests. To illustrate the mechanism involved in cellulose digestion, the cellulolytic activity and zymography in the gut contents of 16 locust species were determined using carboxymethyl cellulose (CMC) as substrate. .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.29.6
- DOI:
- 10.4238/2014.September.29.6
Molecular cloning and analysis of a receptor-like promoter of Gbvdr3 gene in sea island cotton
Authors: B.-J. Zhang, H.-P. Zhang, Q.-Z. Chen, N. Tang, L.-K. Wang, R.-F. Wang and B.-L. Zhang
Verticillium wilt caused by soil borne fungus Verticillium dahliae could significantly reduce cotton yield. The Ve1 homologous gene Gbvdr3 is resistant to Verticillium wilt. In order to understand of the function of the promoter Gbvdr3 in Gossypium barbadense, the promoter region of the receptor-like gene Gbvdr3 was obtained b.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028636
- DOI:
- 10.4238/gmr.15028636
Multi-threading the generation of Burrows-Wheeler Alignment
Authors: H. Jo
Along with recent progress in next-generation sequencing technology, it has become easier to process larger amounts of genome sequencing data at a lower cost. The most time-consuming step of next-generation sequencing data analysis involves the mapping of read data into a reference genome. Although the Burrows-Wheeler Alignmen.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028650
- DOI:
- 10.4238/gmr.15028650
Molecular characterization and expression analysis of the Lrh-1 gene in Chinese Hu sheep
Authors: L.H. Wang, W. Zhang, J.L. Ji, Q.X. Gao, S.H. Xiao and F. Wang
Liver receptor homologue 1 (Lrh-1) is a member of the nuclear receptor belonging to the second subfamily of the nuclear receptor family 5A (NR5A), also named NR5A2, which is important for lipid homeostasis, embryogenesis, and regulation of aromatics. The present study aimed to understand the sequence of ovine Lrh-1 and the expression traits in reproductiv.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.6.2
- DOI:
- 10.4238/2013.May.6.2
Gene expression profile and enrichment pathways in different stages of bladder cancer
Authors: Z.-Q. Fang, W.-D. Zang, R. Chen, B.-W. Ye, X.-W. Wang, S.-H. Yi, W. Chen, F. He and G. Ye
Bladder cancer is a highly heterogeneous neoplasm. We examined the gene expression profile in 3 bladder cancer stages (Ta, T1, T2) using expression microarray analysis of 40 bladder tumors. Differentially expressed genes were found by the t-test, with <0.005 as the significance threshold. KEGG pathway-enrichment analysis was used to study the signaling.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.May.6.1
- DOI:
- 10.4238/2013.May.6.1
Overexpression of soybean R2R3-MYB transcription factor, GmMYB12B2, and tolerance to UV radiation and salt stress in transgenic Arabidopsis
Authors: X.W. Li, Y. Wang, F. Yan, J.W. Li, Y. Zhao, X. Zhao, Y. Zhai and Q.Y. Wang
MYB, v-myb avian myeloblastosis viral oncogene homolog, proteins play central roles in plant stress response. Previously, we identified a novel R2R3-MYB transcription factor, GmMYB12B2, which affected the expression levels of some key enzyme genes involved in flavonoid biosynthesis in transgenic Arabidopsis. In the present stu.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15026573
- DOI:
- 10.4238/gmr.15026573
SSR-based association mapping of salt tolerance in cotton (Gossypium hirsutum L.)
Authors: Y.L. Zhao, H.M. Wang, B.X. Shao, W. Chen, Z.J. Guo, H.Y. Gong,X.H. Sang, J.J. Wang and W.W. Ye
The identification of simple sequence repeat (SSR) markers associated with salt tolerance in cotton contributes to molecular assisted selection (MAS), which can improve the efficiency of traditional breeding. In this study, 134 samples of upland cotton cultivars were selected. The seedling emergence rates were tested under 0.3.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027370
- DOI:
- 10.4238/gmr.15027370
Dietary zinc may attenuate heat-induced testicular oxidative stress in mice via up-regulation of Cu-Zn SOD
Authors: Y. Cao, Y.S. Li, Z.J. Li, F. Wang and C.M. Li
Zinc (Zn) is important for male mammalian reproduction. In this study, we sought to clarify the role of Zn in heat-induced testicular damage in mice. Eighteen mice were divided into either control (con), heat (heat) and heat plus Zn (H+Zn) treatment groups, and fed diets containing 60 (con and heat groups) or 300 (H+Zn group) mg/kg Zn sulfate for one mont.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.11.9
- DOI:
- 10.4238/2015.December.11.9
Molecular characterization and functional analysis of the Nep1-like protein-encoding gene from Phytophthora capsici
Authors: B.Z. Feng and P.Q. Li
Phytophthora capsici is an aggressive plant pathogen that affects solanaceous and cucurbitaceous hosts. Nep1-like proteins (NLPs) are a group of effectors found particularly in oomycetes and considered important virulence factors. We identified an NLP gene (phcnlp1) from the highly virulent P. capsici strain Phyc12 that had an encoded polypeptide of 476-a.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.26.8
- DOI:
- 10.4238/2013.April.26.8