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Human Genetics   Research Article

ERCC2 rs13181 polymorphism association with glioma susceptibility in a Chinese population

Authors: X. Gao, Y.J. Tang, G.F. Zhang, L. Yu and S.T. Qi

We conducted a case-control study to investigate the role of ERCC2 rs13181 polymorphism in glioma development. A total of 165 patients who were histopathologically diagnosed to have gliomas and 330 controls were collected at Jiujiang First People’s Hospital between July 2012 and June 2014. The ERCC2 rs13181 polymorphism .. Read More»

Genet. Mol. Res. 15(2):
gmr.15027585
DOI:
10.4238/gmr.15027585
Microbial Genetics   Research Article

Subtyping Brazilian Yersinia pestis strains by pulsed-field gel electrophoresis

Authors: M.P.S. Barros, V.M. Silveira-Filho, R.H.F.B. Lins, M.B.M. Oliveira, A.M.P. Almeida and T.C. Leal-Balbino

We subtyped Brazilian Yersinia pestis strains by pulsed-field gel electrophoresis (PFGE). This was done with 22 Brazilian Y. pestis strains: 17 from an outbreak and 5 from endemic routine surveillance. The strains were divided into 2 groups (I and II), 8 subgroups (A-H) and 19 PFGE profiles or pulsotypes. PFGE did not separate outbreak from non-outbreak s.. Read More»

Genet. Mol. Res. 12(2):
2013.January.4.23
DOI:
10.4238/2013.January.4.23
Human Genetics   Research Article

Balance between inflammatory and regulatory cytokines in systemic lupus erythematosus

Authors: Y. Yao, J.B. Wang, M.M. Xin, H. Li, B. Liu, L.L. Wang, L.Q. Wang and L. Zhao

To investigate the cytokine profile in serum and cerebrospinal fluid (CSF) from patients with systemic lupus erythematosus (SLE) and central nervous system infection, we measured interferon-g (IFN-g), interleukin-1b (IL-1b), IL-4, IL-6, IL-8, IL-10, and IL-17 levels in serum and CSF from 50 SLE patients and 38 matched controls.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027626
DOI:
10.4238/gmr.15027626
Cytogenomics   Research Article

A proposed model for the flowering signaling pathway of sugarcane under photoperiodic control

Authors: C.P. Coelho, A.P. Costa Netto, J. Colasanti and A. Chalfun-Junior

Molecular analysis of floral induction in Arabidopsis has identified several flowering time genes related to 4 response networks defined by the autonomous, gibberellin, photoperiod, and vernalization pathways. Although grass flowering processes include ancestral functions shared by both mono- and dicots, they have developed their own mechanisms to transmi.. Read More»

Genet. Mol. Res. 12(2):
2013.April.25.6
DOI:
10.4238/2013.April.25.6
Human Genetics   Research Article

Association of CYP1A1 MspI polymorphism with oral cancer risk in Asian populations: a meta-analysis

Authors: J.L. Xu, R. Xia, L. Sun, X. Min, Z.H. Sun, C. Liu, H. Zhang and Y.M. Zhu

Numerous studies regarding the association between the CYP1A1 MspI polymorphism and oral cancer risk in Asian populations have shown controversial results. To get a more precise estimation of this relationship, we conducted a comprehensive meta-analysis. PubMed, the Cochrane Library, Elsevier Science Direct, Web of Knowledge, .. Read More»

Genet. Mol. Res. 15(2):
gmr.15027688
DOI:
10.4238/gmr.15027688
Medical Genetics   Research Article

The insertion/deletion polymorphism in the ACE gene and chronic obstructive pulmonary disease

Authors: S. Simsek, S. Tekes, D. Oral, A. Turkyilmaz, B. Isik, M.R. Isik and H. Akkoc

An insertion/deletion (I/D) polymorphism was identified in intron 16 of the gene encoding the human angiotensin I-converting enzyme (ACE), a candidate gene for chronic obstructive pulmonary disease (COPD). We investigated the relationship between this polymorphism in the ACE gene and the risk of developing COPD. Sixty-six COPD in-patients and 40 non-smoki.. Read More»

Genet. Mol. Res. 12(2):
2013.April.25.10
DOI:
10.4238/2013.April.25.10
Plant Genetics   Research Article

Genome-wide analysis of TCP family in tobacco

Authors: L. Chen, Y.Q. Chen, A.M. Ding, H. Chen, F. Xia, W.F. Wang and Y.H. Sun

The TCP family is a transcription factor family, members of which are extensively involved in plant growth and development as well as in signal transduction in the response against many physiological and biochemical stimuli. In the present study, 61 TCP genes were identified in tobacco (Nicotiana tabacum) genome. Bioinformatic.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027728
DOI:
10.4238/gmr.15027728
Human Genetics   Research Article

Decreased miR-452 expression in human colorectal cancer and its tumor suppressive function

Authors: T. Tang, G.C. Zhang, C.F. Li, Y.F. Liu and W.Y. Wang

 -.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027730
DOI:
10.4238/gmr.15027730
Cytogenomics   Research Article

Evaluation of genetic diversity in fig accessions by using microsatellite markers

Authors: A.D.B. do Val, C.S. Souza, E.A. Ferreira, S.M.L. Salgado, M. Pasqual and G.M.A. Can�§ado

Fig (Ficus carica L.) is a fruit of great importance worldwide. Its propagation is carried out with stem cuttings, a procedure that favors the occurrence of synonymy among specimens. Thus, molecular markers have become an important tool for studies of DNA fingerprinting, germplasm characterization, and genetic diversity evaluation in this plant species. T.. Read More»

Genet. Mol. Res. 12(2):
2013.April.25.9
DOI:
10.4238/2013.April.25.9
Microbial Genetics   Research Article

Isolation and characterization of microsatellite markers in Ruditapes philippinarum

Authors: Z.B. Li, Y.F. Ning, J.B. Shangguan, B.B. Li, X.Q. Mao, Y.S. Huang and Y. Yuan

Ruditapes philippinarum is considered a commercially valuable species, which is commonly found in tidal flats along West Pacific coasts. In China, it is mainly distributed in the southeast sea. In this study, 16 novel microsatellite loci from the R. philippinarum genome were developed, using the protocol of fast isolation by a.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027742
DOI:
10.4238/gmr.15027742