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Microbial Genetics   Research Article

Molecular cloning and tissue expression analyses of two novel pepper genes: heterotrimeric G protein beta 2 subunit and ArcA1

Authors: M.H. Deng, J.L. Huo, H.S. Zhu, H. Zhou and J.F. Wen

We isolated two transcription factor genes, heterotrimeric G protein beta 2 subunit (Gβ2) and ArcA1, from pepper (Capsicum annuum). The complete coding sequences were amplified using reversed transcriptase PCR based on conserved sequence information of Solanum lycopersicum and several other plant species. Nucleotide sequence analysis of these two gen.. Read More»

Genet. Mol. Res. 12(2):
2013.April.17.1
DOI:
10.4238/2013.April.17.1
Human Genetics   Research Article

Tristetraprolin: a novel mediator of the anticancer properties of resveratrol

Authors: C. Li, C. Tang and G. He

Resveratrol is a natural compound that exhibits anticancer properties. Previous studies have proved that it can inhibit the proliferation of breast cancer cell lines and upregulate some cytokines such as cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF). The initiation and progression of cancer are associa.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027213
DOI:
10.4238/gmr.15027213
Cytogenomics   Research Article

Cassava interspecific hybrids with increased protein content and improved amino acid profiles

Authors: P.T.C. Gomes and N.M.A. Nassar

Cassava (Manihot esculenta) is a principal food for large populations of poor people in the tropics and subtropics. Its edible roots are poor in protein and lack several essential amino acids. Interspecific hybrids may acquire high protein characteristics from wild species. We analyzed 19 hybrids of M. esculenta with its wild relative, M. oligantha, for c.. Read More»

Genet. Mol. Res. 12(2):
2013.April.12.8
DOI:
10.4238/2013.April.12.8
Medical Genetics   Research Article

Correlation between the genetic polymorphism of ORMDL3 gene and asthma risk:a meta-analysis

Authors: W.H. Zhai, C.Y. Song, Z.G. Huang and H. Sha

While increasing scientific evidence suggests that the ORMDL3 rs7216389 polymorphism may contribute to a higher susceptibility to asthma, many of the current studies have yielded inconclusive results. This meta-analysis aimed to assess the association between the ORMDL3 rs7216389 polymorphism and the risk of asthma. An extensive literature search for rele.. Read More»

Genet. Mol. Res. 14(2):
2015.June.29.3
DOI:
10.4238/2015.June.29.3
Animal Genetics   Research Article

Protective effect of necrostatin-1 on myocardial tissue in rats with acute myocardial infarction

Authors: Y.R. Liu and H.M. Xu

The aim of this study was to investigate the protective effect of necrostatin-1 on myocardial tissue of acute myocardial infarction (AMI) rats and to provide a basis for necrostatin-1 for the treatment of acute myocardial infarction. AMI rats (45) were established by ligating the anterior descending branch of the left coronary.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027298
DOI:
10.4238/gmr.15027298
Animal Genetics   Research Article

Effect of siRNA silencing of inducible co-stimulatory molecule on myocardial cell hypertrophy after cardiac infarction in rats

Authors: W.M. Wang, Z. Liu and G. Chen

As the most common cardiac disease, myocardial infarction is followed by hypertrophy of cardiac myocytes and reconstruction of ventricular structure. The up-regulation of a series of factors including metalloproteinases, inflammatory factors, and growth factors after primary infarction lead to the hypertrophy, apoptosis, necro.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027338
DOI:
10.4238/gmr.15027338
Cytogenomics   Research Article

Genetic diversity in wild Dipsacus chinensis populations from China based on ISSR markers

Authors: D.-X. Chen, L.-Y. Li, X. Zhang, Y. Wang and Z. Zhang

Wild Dipsacus chinensis plants in China have become endangered owing to over-harvesting and habitat fragmentation. We examined the genetic diversity and genetic structure of 90 individuals from three populations using inter-simple sequence repeat markers and found that 106 of 173 bands amplified by 22 informative and reliable primers were polymorphic. The.. Read More»

Genet. Mol. Res. 12(2):
2013.April.12.7
DOI:
10.4238/2013.April.12.7
Human Genetics   Research Article

Changes in growth factor levels in the cerebrospinal fluid of autism patients after transplantation of human umbilical cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells

Authors: Q. Li, C.-F. Chen, D.-Y. Wang, Y.-T. L�¼, Y. Huan, S.-X. Fang,Y. Han, R.-C. Ge and X.-W. Ch

 -.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027526
DOI:
10.4238/gmr.15027526
Human Genetics   Research Article

Myoglobin A79G polymorphism association with exercise-induced skeletal muscle damage

Authors: T. Cui and M.S. Jiang

We assessed the role of A79G, a polymorphism of the myoglobin gene (MB), in susceptibility to exercise-induced skeletal muscle damage. Between January 2012 and December 2014, a total of 166 cases with exercise-induced skeletal muscle damage and 166 controls were recruited into our study. Genotyping of MB A79G was carried out u.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027506
DOI:
10.4238/gmr.15027506
Cytogenomics   Research Article

Construction of suppressor of cytokine signaling 2 (SOCS2) adenoviral overexpression vector and its impact on growth hormone- induced lipolysis in swine primary adipocytes

Authors: H.L. Yang, J. Yan, M. Feng, X. Tan, G.Y. Yan, L. Gan and C. Sun

We investigated the effect of overexpression suppressor of cytokine signaling 2 (SOCS2) on lipolysis in swine primary adipocytes (pAd) induced by growth hormone (GH). We constructed pAd-SOCS2 adenoviral overexpression vectors to infect HEK293 cells for virus packaging and propagation. Cultured swine primary adipocytes were infected with virus particles; a.. Read More»

Genet. Mol. Res. 12(2):
2013.January.9.2
DOI:
10.4238/2013.January.9.2