Association of MyoD1a and MyoD1b gene polymorphisms and meat quality traits in rainbow trout
Authors: W.X. Chen, Y. Ma and K.H. Liu
In this study, we identified myogenic regulatory factors (MRFs) and analyzed the correlation between MRFs and meat quality in rainbow trout. The MyoD1a and MyoD1b genes were cloned from rainbow trout using a homology cloning method. Introns 1 and 2 in the MyoD1a and MyoD1b genes were cloned and submitted to GenBank (accession Nos. FJ623462 and FJ793566). .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.12
- DOI:
- 10.4238/2015.August.7.12
Association between MTHFR 677C/T polymorphism and psoriasis risk:a meta-analysis
Authors: J.H. Qi,J.H. Qi,N. Shi,Y.J. Chen and G. Nie
Previous studies investigating the association between methylenetetrahydrofolate reductase (MTHFR) 677C/T polymorphisms and psoriasis risk have reported inconsistent results. The present meta-analysis aimed to comprehensively evaluate the association between MTHFR 677C/T polymorphism and psoriasis risk. The studies regarding the association between MTHFR .. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.22.16
- DOI:
- http://dx.doi.org/10.4238/2015.April.22.16
Diagnostic performance of anti-citrullinated protein/peptide antibodies in juvenile idiopathic arthritis
Authors: S.Y. Pang, H.Y. Liu, Y.J. Huang, Y.F. Liu, Y.M. Dai, P. Zeng and H.S. Zeng
The prevalence rates of anti-citrullinated protein/peptide antibodies (ACPAs) were investigated in a cohort of juvenile idiopathic arthritis (JIA) patients, and their diagnostic performances were compared. ACPAs, including anti-cyclic citrullinated peptide IgG (anti-CCP), anti-CCP IgG/IgA (anti-CCP3.1), citrullinated recombina.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028641
- DOI:
- 10.4238/gmr.15028641
Role of inflammatory responses in the pathogenesis of human cerebral aneurysm
Authors: X.J. Fan, H.D. Zhao, G. Yu, X.L. Zhong, H. Yao and Q.D. Yang
We aimed to detect expressional profiles of intracellular cell adhesion molecule-1 (ICAM-1), nuclear factor-kappa B (NF-κB), and monocyte chemoattractant protein-1 (MCP-1) in human cerebral aneurysm, in order to investigate the effect of chronic inflammation on the pathogenesis of cerebral aneurysm. Samples from 40 cases of human cerebral aneurysms .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.15
- DOI:
- 10.4238/2015.August.7.15
Mechanisms of cytotoxicity induced by the anesthetic isoflurane: the role of inositol 1,4,5-trisphosphate receptors
Authors: W.-H. Zhai, J. Zhao, S.-P. Huo, X.-G. Chen, Y.-D. Li, Z.-L. Zhang, L.-L. Yu, S. Song and Q.-J. Wang
Isoflurane can induce widespread cytotoxicity. We hypothesized that isoflurane induces apoptosis partly by causing excessive calcium release from the endoplasmic reticulum (ER) via direct activation of inositol 1,4,5-trisphosphate receptors (IP3 R). Rat pheochromocytoma cells cultured for seven days with nerve growth factor were divided into four groups: .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.26.1
- DOI:
- 10.4238/2015.June.26.1
Cytogenetic and protein quantification in polyploid somatic tissue of Myrmeleon uniformis (Neuroptera, Myrmeleontidae)
Authors: C.A. Pacheco,T.L. da Silva and M.K.H. Kobayashi
Myrmeleon unifomis Malpighian tubules cells were analyzed under two aspects: chromatin structure and total protein quantification in the three larval phases (L1, L2 and L3) and in adults. This insect Malpighian tubules present polyploid tissue resultant from endoreduplication, which probably begins in the first larval phases. The Malpighian tubule proxima.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.27.1
- DOI:
- http://dx.doi.org/10.4238/2015.April.27.1
Association between 1p13.3 genomic markers and coronary artery disease: a meta-analysis involving patients and controls
Authors: J. Guo, Y.X. Luo, L.X. Tao1 and X.H. Guo
Recently, genome-wide association studies on cardiovascular disease identified a series of associated single nucleotide polymorphisms in an intergenic region of chromosome 1p13.3. We investigated the association of this locus with cardiovascular disease in 13 case-control studies and undertook a meta-analysis for effect size, heterogeneity, publ.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.18
- DOI:
- 10.4238/2015.August.7.18
Clinical significance and levels of blood brain natriuretic peptides in patients with persistent atrial fibrillation before and after catheter ablation
Authors: S.Y. Xing, H.L. Wang, P.S. Dong, L.H. Lai, J.H. Zhu, J.F. Zhao and X.Y. Shang
The aim of this study was to observe levels of blood brain natriuretic peptides (BNPs) in patients with persistent atrial fibrillation (AF) before and after catheter ablation. Thirty-six patients with persistent AF (28 successful surgeries and eight recurrent cases) and 36 healthy controls with normal sinus rhythm were recruited for this study. BNP levels.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.26.3
- DOI:
- 10.4238/2015.June.26.3
Inhibitory effect of ursolic acid and oleanolic acid from Eriobotrya fragrans on A549 cell viability in vivo
Authors: Y.S. Gao, Y. Yuan, G. Song and S.Q. Lin
Loquat [Eriobotrya japonica (Lindl.)] is a traditional Chinese medicine, which has been used as an anti-inflammatory and for curing chronic bronchitis among other potential applications. Extracted ursolic acid (UA) and oleanolic acid (OA) from wild loquat were previously found capable of suppressing the proliferation of A549 c.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028642
- DOI:
- 10.4238/gmr.15028642
Vitamin D receptor gene FokI, TaqI, BsmI, and ApaI polymorphisms and susceptibility to pulmonary tuberculosis: a meta-analysis
Authors: Y.H. Lee and G.G. Song
The aim of this study was to determine whether vitamin D receptor (VDR) genetic polymorphisms are associated with the susceptibility to pulmonary tuberculosis (PTB). MEDLINE and Embase databases and manual literature searches were used. A meta-analysis was conducted on the associations between the VDR FokI, TaqI, BsmI, and ApaI polymorphisms and PTB susce.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.7.21
- DOI:
- 10.4238/2015.August.7.21