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Medical Genetics   Research Article

T174M polymorphism in the angiotensinogen gene and risk of myocardial infarction: ameta-analysis

Authors: P.Y. Hu,Y.W. Wang,X.H. Pang and H.W. Wang

Numerous studies have evaluated the association between the T174M polymorphism in the angiotensinogen (AGT) gene and myocardial infarction (MI) risk. However, the specific association remains controversial because of small sample sizes and varied study designs among different studies. We performed a meta-analysis to assess this correlation. A comprehensiv.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.22.5
DOI:
http://dx.doi.org/10.4238/2015.April.22.5
Microbial Genetics   Research Article

Characterization of microsatellite markers and their correlations with growth traits in Mandarin fish (Siniperca chuatsi)

Authors: T.L. Yi, L. Fang, X.F. Liang, L.F. Sun, J. Li, X.N. Luo, W.J. Guo, Y.Q. Dou and J. Sun

Mandarin fish (Siniperca chuatsi) is a traditionally cultured freshwater fish with high commercial value in China. To facilitate marker-assisted selection for genetic improvement of this species, 100 microsatellite markers identifi ed in previous studies were characterized in the 25 largest and 25 smallest individuals. Twenty polymorphic loci were used to.. Read More»

Genet. Mol. Res. 14(3):
2015.August.7.1
DOI:
10.4238/2015.August.7.1
Human Genetics   Research Article

Development and characterization of microsatellite markers for Ulmus chenmoui (Ulmaceae), an endangered tree endemic to eastern China

Authors: Q.F. Geng, J. He, J. Yang, E. Shi, D.B. Wang, W.X. Xu,N. Jeelani Z.S. Wang and H. Liu

Ulmus chenmoui (Ulmaceae) is an endangered tree found on Langya Mountain, eastern China. To better understand the population genetics of U. chenmoui and conserve the species, we developed microsatellite markers. Using a suppression-polymerase chain reaction technique, 74 compound microsatellite primer pairs were designed. Twel.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027985
DOI:
10.4238/gmr.15027985
Microbial Genetics   Research Article

Analysis of genetic diversity identified by amplified fragment length polymorphism marker in hybrid wheat

Authors: M. Ejaz, Z. Qidi, Z. Gaisheng, N. Na, Z. Huiyan and W. Qunzhu

Amplified fragment length polymorphism markers were used to assess genetic diversity in 10 male sterile wheat crop lines (hetero-cytoplasm with the same nucleus) in relation to a restorer wheat line. These male sterile lines were evaluated using 64 amplified fragment length polymorphism primer combinations, and 13 primers produced polymorphic bands, gener.. Read More»

Genet. Mol. Res. 14(3):
2015.August.7.2
DOI:
10.4238/2015.August.7.2
Human Genetics   Research Article

Decreased levels of soluble receptor for advanced glycation end-products in aortic valve calcification patients

Authors: H. Zheng,Y. Li,N. Xie,J.L. Huang,H.F. Xu and M. Luo

The soluble receptor for advanced glycation end-products (sRAGE) shows a close relationship with atherosclerosis. The goal of this study was to compare the levels of sRAGE in patients with and without aortic valve calcification and to investigate the relationship between them. After transthoracic echocardiographic examination, 120 male patients with aorti.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.22.6
DOI:
http://dx.doi.org/10.4238/2015.April.22.6
Microbial Genetics   Research Article

Synonymous codon selection in the hepatitis B virus translation initiation region

Authors: M.-R. Ma, L. Hui, M.-L. Wang, Y. Tang, Y.-W. Chang, Q.-H. Jia, X.-P. Yang, X.-H. Wang and X.-Q. Ha

Hepatitis B virus (HBV) infection is a major health problem worldwide. This virus and its hosts are often fated to continual co-evolutionary interactions. Codon usage analysis has significance for studies of co-evolution between viruses, their hosts, and mRNA translation. Adaptation of the overall codon usage pattern of HBV to that of humans is estimated .. Read More»

Genet. Mol. Res. 14(3):
2015.August.7.4
DOI:
10.4238/2015.August.7.4
Microbial Genetics   Research Article

Association of the p53 Arg72Pro polymorphism with esophageal cancer in Chinese populations: a meta-analysis

Authors: J.Z. Peng, L. Xue, D.G. Liu and Y.H. Lin

Although many epidemiologic studies have investigated the p53 codon 72 polymorphism and its association with esophageal cancer (EC) in China, definite conclusions could not be drawn. To clarify the effects of p53 codon 72 polymorphism on the risk of EC, we performed a meta-analysis on the Chinese population. A total of 13 studies including 3308 patients a.. Read More»

Genet. Mol. Res. 14(3):
2015.August.7.11
DOI:
10.4238/2015.August.7.11
Human Genetics   Research Article

Diallelic analysis to obtain cowpea (Vigna unguiculata L. Walp.) populations tolerant to water deficit

Authors: E.V. Rodrigues, K.J. Damasceno-Silva, M.M. Rocha and E.A. Bastos

The purpose of this study was to identify parents and obtain segregating populations of cowpea (Vigna unguiculata L. Walp.) with the potential for tolerance to water deficit. A full diallel was performed with six cowpea genotypes, and two experiments were conducted in Teresina, PI, Brazil in 2011 to evaluate 30 F2 populations .. Read More»

Genet. Mol. Res. 15(2):
gmr.15027996
DOI:
10.4238/gmr.15027996
Medical Genetics   Research Article

Clinical value of ultrasound-guided percutaneous biopsy of pulmonary lesions

Authors: R.J. Yang,Y.L. Yang,L.T. Ruan,L.J. Yuan,L.J. Chao,S. Chen and Y.Y. Duan

The purpose of this study was to evaluate the applicability of ultrasound-guided percutaneous biopsy for the diagnosis and differentiation of various pulmonary lesions in a Chinese population. A total of 338 pulmonary lesions were biopsied with 18-gauge cutting needles, guided by ultrasound, and sent for histopathological analysis. The ultrasonographic ch.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.22.7
DOI:
http://dx.doi.org/10.4238/2015.April.22.7
Microbial Genetics   Research Article

Sex identification based on AMEL gene PCR amplification from blue sheep (Pseudois nayaur) fecal DNA samples

Authors: X. Liu, Y.Y. Yang, X.M. Wang, Z.S. Liu, Z.H. Wang and Y.Z. Ding

The use of noninvasive genetic sampling to identify the sex of wild animals is an extremely valuable and important tool in molecular ecology and wildlife conservation. Sex determination using the amelogenin gene has been conducted in many species because only a single pair of primers is required to amplify both X- and Y-linked alleles. However, this metho.. Read More»

Genet. Mol. Res. 14(3):
2015.August.7.13
DOI:
10.4238/2015.August.7.13