All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Plant Genetics   Research Article

Construction of an integrated genetic map for Capsicum baccatum L.

Authors: M.M. Moulin, R. Rodrigues, H.C.C. Ramos, C.S. Bento, C.P. Sudr�©, L.S.A. Gon�§alves and A.P. Viana

Capsicum baccatum L. is one of the five Capsicum domesticated species and has multiple uses in the food, pharmaceutical and cosmetic industries. This species is also a valuable source of genes for chili pepper breeding, especially genes for disease resistance and fruit quality. However, knowledge of the genetic structure of C. baccatum is limited. A refer.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.12
DOI:
10.4238/2015.June.18.12
Plant Genetics   Research Article

Improving plant transformation using Agrobacterium tumefaciens

Authors: L.V. Ribeiro Neto, A.P. Oliveira, M.V. Louren�§o, B.W. Bertoni, S.C. Fran�§a, T.M. Rosa-Santos and S.M. Zingaretti

Here, we report a quick and low-cost method to improve plant transformation using Agrobacterium tumefaciens. This method involves the use of physical wounding, ultrasound, and an increase in exposure time to the bacteria. We show how the transformation rate increased from 0 to 14% when an ultrasound pulse of 10 s was used in conjunction with 96 h of bacte.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.13
DOI:
10.4238/2015.June.18.13
Animal Genetics   Research Article

Association between FTO polymorphism in exon 3 with carcass and meat quality traits in crossbred ducks

Authors: W. Gan, Q. Song, N.N. Zhang, X.P. Xiong, D.M.C. Wang and L. Li

The fat mass and obesity-associated gene (FTO) is an excellent candidate gene that affects energy metabolism. Single nucleotide polymorphisms (SNPs) in FTO are associated with carcass and meat quality traits in pigs, cattle, and rabbits. The aim of this study was to investigate the association between novel SNPs in the FTO coding region and carcass and me.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.14
DOI:
10.4238/2015.June.18.14
Animal Genetics   Research Article

Hypoxia-inducible factor-1�± expression in the different stages of rat thromboangiitis obliterans

Authors: T. He, B.H. Qu, D.L. Wang and M. Hu

We investigated the expression and effects of hypoxiainducible factor-1α (HIF-1α) in rat thromboangiitis obliterans (TO). Rats were divided into sham and model groups. The model group was further divided into groups based on observation duration. Lauric acid was injected below an artery clamp to simulate TO in the model group; saline was used .. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.15
DOI:
10.4238/2015.June.18.15
Microbial Genetics   Research Article

Detection of drug-resistance mechanism of Pseudomonas aeruginosa developing from a sensitive strain to a persister during carbapenem treatment

Authors: J.L. Shen and Y.P. Fang

We explored the mechanism of the development from sensitivity to resistance to carbapenem in Pseudomonas aeruginosa. Two P. aeruginosa strains were collected during treatment with carbapenem. Strain homology was investigated using pulsed-field gel electrophoresis. Porin oprD2 expression was analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophor.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.16
DOI:
10.4238/2015.June.18.16
Human Genetics   Research Article

Relationship between zinc finger protein 36 (ZFP36) gene polymorphisms and obstructive sleep apnea

Authors: Y. Zhang, N.-F. Li, S. Abulikemu, D.-L. Zhang, Y.-C. Wang, J.-Q. Kong, G.-L. Nuer, Z.-T. Yan, H.-J. Li, J.-H. Zhang and X.-Y. Zhang

Recent data have indicated that inflammation may have an important correlation with obstructive sleep apnea (OSA). Studies have indicated a relationship between OSA and TNF-α gene polymorphisms. Zinc finger protein 36 (ZFP36) regulates TNF-α mRNAs. However, ZFP36 gene polymorphisms have not been investigated in OSA. Therefore, we conducted the.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.17
DOI:
10.4238/2015.June.18.17
Bioinformatics   Research Article

Multi-objective optimization in systematic conservation planning and the representation of genetic variability among populations

Authors: S. Schlottfeldt, M.E.M.T. Walter, A.C.P. L.F. Carvalho, T.N. Soares, M.P.C. Telles, R.D. Loyola and J.A.F. Diniz-Filho

Biodiversity crises have led scientists to develop strategies for achieving conservation goals. The underlying principle of these strategies lies in systematic conservation planning (SCP), in which there are at least 2 conflicting objectives, making it a good candidate for multi-objective optimization. Although SCP is typically applied at the species leve.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.18
DOI:
10.4238/2015.June.18.18
Human Genetics   Research Article

Evaluation of the efficiency of artificial neural networks for genetic value prediction

Authors: G.N. Silva, R.S. Tomaz, I.C. Sant�Anna, V.Q. Carneiro, C.D. Cruz and M. Nascimento

Artificial neural networks have shown great potential when applied to breeding programs. In this study, we propose the use of artificial neural networks as a viable alternative to conventional prediction methods. We conduct a thorough evaluation of the efficiency of these networks with respect to the prediction of breeding values. Therefore, we considered.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017676
DOI:
10.4238/gmr.15017676
Medical Genetics   Research Article

Correlation between promoter methylation in the GSTP1 gene and hepatocellular carcinoma development: a meta-analysis

Authors: Q.F. Li, Q.Y. Li, A.R. Gao and Q.F. Shi

Epigenetic silencing of the GSTP1 gene by promoter methylation has been associated with increased risk and shortened survival in patients with hepatocellular carcinoma (HCC). We therefore conducted a meta-analysis to obtain a more precise estimate of this association. By searching the Cochrane Library, CBM, EMBASE, PubMed, and the Web of Science, we tabul.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.19
DOI:
10.4238/2015.June.18.19
Bioinformatics   Research Article

Differential gene expression in pre-laying and laying period ovaries of Sichuan White geese (Anser cygnoides)

Authors: N. Ding, Q. Han, X.Z. Zhao, Q. Li, J. Li, H.F. Zhang, G.L. Gao,Y. Luo, Y.H. Xie, J. Su and Q.G. Wang

Geese are an economically important poultry species worldwide. Their superior meat production performance and meat quality make them a popular food. However, they are not bred worldwide because their poor laying capacity increases farming costs. To gain a global view of the genes that are differentially expressed between prelaying (P) and laying (L) perio.. Read More»

Genet. Mol. Res. 14(2):
2015.June.18.20
DOI:
10.4238/2015.June.18.20