Microsatellite markers in Paulownia kawakamii (Scrophulariaceae) and cross-amplification in other Paulownia species
Authors: H.W. Wang, J.M. Duan, P. Zhang, Y.Q. Cheng, J.W. Wu and G.Z. Wang
Paulownia kawakamii is a fast-growing timber tree. In this study, 21 primer sets were developed using an enriched genomic library. The genetic diversity was measured in one P. kawakamii population. The number of alleles per locus ranged from 2 to 19. The observed and expected heterozygosities varied from 0.158 to 0.842 (mean = 0.421) and from 0.376 to 0.9.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.19.6
- DOI:
- 10.4238/2013.September.19.6
Functional polymorphisms of the cyclooxygenase-2 gene and prognosis of hepatocellular carcinoma - a cohort study in Chinese people
Authors: R. Liang, X.X. Yan, Y. Lin, Q. Li, C.L. Yuan, Z.H. Liu and Y.Q. Li
Cyclooxygenase-2 (COX-2) influences carcinogenesis through regulation of angiogenesis, apoptosis, cytokine expression, and immune response suppression. It has been well established that COX-2 is overexpressed in a variety of human cancers, such as hepatocellular carcinoma (HCC). In this study, we aimed to evaluate the associat.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028093
- DOI:
- 10.4238/gmr.15028093
miR-133 inhibits pituitary tumor cell migration and invasion via down-regulating FOXC1 expression
Authors: D.S. Wang, H.Q. Zhang, B. Zhang, Z.B. Yuan, Z.K. Yu, T. Yang, S.Q. Zhang, Y. Liu and X.X. Jia
Many studies have shown that microRNA (miR)-133 functions as a tumor suppressor in a variety of metastatic cancers, including breast cancer, gastric cancer, and liver fibrosis. However, the influence of miR-133 on pituitary tumor malignancy has not yet been reported. The purpose of this study was to explore the role of miR-133.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017453
- DOI:
- 10.4238/gmr.15017453
Influences of species mixture on biomass of Masson pine (Pinus massoniana Lamb) forests
Authors: L.F. Zhang, Y.Y. Huang, L.P. Liu and S.L. Fu
The effect of tree diversity on productivity in subtropical forests in China is poorly understood. We investigated the biomasses of trees, understory vegetation, coarse roots, and fine roots with varying proportions of Pinus massoniana, mixed with other tree species in stands of the same age, to examine the effects of tree diversity. With an increase of P.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.19.5
- DOI:
- 10.4238/2013.September.19.5
Association between the expression of HIF-1�± and VEGF and prognostic implications in primary liver cancer
Authors: L.Y. Guo, P. Zhu and X.P. Jin
The goal of this study was to investigate the expression of hypoxia-inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) in primary liver cancer (PLC) and their association with prognosis. Tumor tissue, non-tumor tissue, and blood samples of 75 PLC patients were collected. Blood samples of 20 .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028107
- DOI:
- 10.4238/gmr.15028107
Analysis of FOS, BTG2, and NR4A in the function of renal medullary hypertension
Authors: Y.B. Wu, W.D. Zang, W.Z. Yao, Y. Luo, B. Hu, L. Wang and Y.L. Liang
The aim of this study was to identify differentially expressed genes (DEGs) in renal medullary hypertension and reveal their pathogenic mechanisms. We downloaded the gene expression profile of GSE28360 from the Gene Expression Omnibus database. The profile included 14 samples (5 normal and 9 hypertension). The DEGs in normal and disease samples were disti.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.19.4
- DOI:
- 10.4238/2013.September.19.4
Common variant rs7579169 is associated with preeclampsia in Han Chinese women
Authors: L.F. Guo, Z.H. Wang and Y.F. Wang
As a heterogeneous group of disorders in pregnancy, many genetic factors are involved in the development of preeclampsia. The single nucleotide polymorphism (SNP) rs7579169, located on chromosome 2q14.2, has been shown to be associated with pregnancy-induced hypertension in Europeans. In this study, we examined whether the SNP.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028114
- DOI:
- 10.4238/gmr.15028114
Protective effect of the n-butanol Toona sinensis seed extract on diabetic nephropathy rat kidneys
Authors: W.Z. Li, X.H. Wang, H.X. Zhang, S.M. Mao and C.Z. Zhao
The objective of this study was to observe the protective effect of the n-butyl alcohol phase of Toona sinensis seed extract on the kidneys of diabetic nephropathy (DN) rats and its preliminary mechanism. Male wistar rats were administered a normal or high-fat diet for 1 month. DN rats were divided into a model group and a pet.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017403
- DOI:
- 10.4238/gmr.15017403
Effect of overexpression of PTEN on apoptosis of liver cancer cells
Authors: M.F. Li, H. Guan and D.D. Zhang
Liver cancer is a common malignant tumor associated with a short-survival period and high-mortality rate, and its prevalence in China is particularly high. This study aimed to investigate the effect of overexpressing the phosphatase and tensin homolog deleted on chromosome 10 (PTEN) gene on liver cancer cell apoptosis and prov.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028120
- DOI:
- 10.4238/gmr.15028120
Genomic DNA isolation of Acrocomia aculeata (Arecaceae) from leaf and stipe tissue samples for PCR analysis
Authors: E.C.M. Lanes, C. Nick, K.N. Kuki, R.D. Freitas and S.Y. Motoike
Macaw palm, Acrocomia aculeata is an oleaginous species of the Arecaceae family; it has been identified as one of the most promising plants for sustainable production of renewable energy, especially biodiesel. We developed an efficient protocol of genomic DNA extraction for A. aculeata using leaf and stipe tissues, based on the cationic hexadecyltrimethyl.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.23.9
- DOI:
- 10.4238/2013.September.23.9