Expression and enzymatic activity of phenylalanine ammonia-lyase and p-coumarate 3-hydroxylase in mango (Mangifera indica �Ataulfo�) during ripening
Authors: H. Palafox-Carlos, C.A. Contreras-Vergara, A. Muhlia-Almaz�¡n, M.A. Islas-Osuna and G.A. Gonz�¡lez-Aguilar
Phenylalanine ammonia lyase (PAL) and p-coumarate 3-hydroxylase (C3H) are key enzymes in the phenylpropanoid pathway. The relative expression of PAL and C3H was evaluated in mango fruit cultivar ‘Ataulfo’ in four ripening stages (RS1, RS2, RS3, and RS4) by quantitative polymerase chain reaction. In addition, enzyme.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.16.10
- DOI:
- http://dx.doi.org/10.4238/2014.May.16.10
Estimates of genetic parameters for total milk yield over multiple ages in Brazilian Murrah buffaloes using different models
Authors: R.C. Sesana, F. Baldi, R.R.A. Borquis, A.B. Bignardi, N.A. Hurtado-Lugo, L. El Faro, L.G. Albuquerque and H. Tonhati
The objective of this study was to estimate variance components and genetic parameters for accumulated 305-day milk yield (MY305) over multiple ages, from 24 to 120 months of age, applying random regression (RRM), repeatability (REP) and multi-trait (MT) models. A total of 4472 lactation records from 1882 buffaloes of the Murr.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.14.7
- DOI:
- 10.4238/2014.April.14.7
Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations
Authors: L.S. Wang, Y. Jiao, Y. Huang, X.Y. Liu, G. Gibson, B. Bennett,K.M. Hamre, D.W. Li, H.Y. Zhao, J. Gelernter, H.R. Kranzler,L.A. Farrer, L. Lu, Y.J. Wang, W.K. Gu
In prior work, congenic strains carrying the DBA/2Igb (D2) region of chromosome 2 (Chr2) for alcohol preference were bred onto a C57BL/6Ibg (B6) background and as predicted were found to reduce voluntary consumption. Subsequently, interval-specific congenic recombinant strains (ISCRS) were generated and also tested. These ISCR.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.26.9
- DOI:
- 10.4238/2013.November.26.9
A preliminary mutation analysis of phenylketonuria in southwest Iran
Authors: N. Ajami1*, S.R. Kazeminezhad1*, A.M. Foroughmand1, M. Hasanpour1 and M. Aminzadeh2
Phenylketonuria (PKU) is a heterogeneous and autosomal recessive metabolic disorder that is mainly caused by mutations in the hepatic phenylalanine hydroxylase (PAH) gene. This study was designed to identify PAH mutations within exons 6, 7, and 10-12 in PKU patients from southwest Iran. Forty Iranian patients with clinical and biochemically confirmed PKU .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.24.7
- DOI:
- 10.4238/2013.October.24.7
Olfactory mucosal microstructural changes in a rat model of acute rhinosinusitis with dysosmia
Authors: J. Ye, J.P. He and Z.J. Liu
This study aimed to examine olfactory mucosal changes in a rat model of acute rhinosinusitis and to determine how acute rhinosinusitis induces dysosmia. Total 100 rats were divided into the experimental (N = 80) and control (N = 20) groups. An acute rhinosinusitis model was established in the experimental rats. From the experi.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.16.11
- DOI:
- http://dx.doi.org/10.4238/2014.May.16.11
Effect of phytosterols on rumen fermentation in vitro
Authors: Y.M. Xi, Z.H. Jin, L.J. Lin and Z.Y. Han
We investigated the effect of phytosterols on rumen fermentation in vitro using gas syringes as incubators. Phytosterols were dissolved in ethyl acetate (8.3%) and added at various concentrations to the common diet in rumen fluid. In vitro gas production (GP) was recorded after 3, 6, 12, 18, and 24 h incubation. Incubation was.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.16.12
- DOI:
- http://dx.doi.org/10.4238/2014.May.16.12
Plasma chemerin level in metabolic syndrome
Authors: D. Wang, G.-Y. Yuan, X.-Z. Wang, J. Jia, L.-L. Di, L. Yang, X. Chen,F.-F. Qian and J.-J. Chen
To investigate the chemerin level in the Chinese Han population with metabolic syndrome and its relationship with each metabolic syndrome component [body mass index (BMI), blood pressure, blood lipids, and blood glucose], we selected 30 patients with metabolic syndrome and 30 healthy control subjects. The chemerin level was me.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.26.8
- DOI:
- 10.4238/2013.November.26.8
Molecular and biochemical characterization of the effects of insecticidal toxin from meloidae beetles on Helicoverpa armigera (Hub.) (Lepidoptera: Noctuidae)
Authors: R.A. Khan1, M. Rashid1, D. Wang2 and Y.L. Zhang1
The molecular and biochemical effects of an insecticidal toxin extracted from Meloidae beetles were investigated on Helicoverpa armigera. The toxin was identified as cantharidin, a well-known natural compound produced by beetles of family Meloidae and Oedemeridae. Furthermore, the effect of the toxin on the metabolic enzymes alkaline phosphatase (ALP) and.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.10.5
- DOI:
- 10.4238/2013.October.10.5
Full-length cDNA cloning and structural characterization of preproinsulin in Alligator sinensis
Authors: R. Zhang, S.Z. Zhang, E. Li, C. Wang, C.L. Wang and X.B. Wu
Insulin is an important endocrine hormone that plays a critical physiological role in regulating metabolism and glucostasis in vertebrates. In this study, the complete cDNA of Alligator sinensis preproinsulin gene was cloned for the first time by reverse transcription-polymerase chain reaction and rapid amplification of cDNA ends methods; the amino acid s.. Read More»
- Genet. Mol. Res. 13(4):
Azithromycin enhances the favorable results of paclitaxel and cisplatin in patients with advanced non-small cell lung cancer
Authors: D.J. Chu, D.E. Yao, Y.F. Zhuang, Y. Hong, X.C. Zhu, Z.R. Fang, J. Yu and Z.Y. Yu
Although new chemotherapeutic drugs have been applied constantly, their efficacy for non-small cell lung cancer (NSCLC) is still not satisfactory. In recent years, epidemiological investigations have shown that lung cancer may be induced by chronic Chlamydia pneumoniae (Cpn) infection, since stable high titers of Cpn antibodie.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.14.8
- DOI:
- 10.4238/2014.April.14.8