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Medical Genetics   Research Article

Evaluation of the function status of the ulnar nerve in carpal tunnel syndrome

Authors: J. Zhang,N. Liu,Y.W. Wang,Z.C. Zhang,L.N. Zheng and J. Zhu

Many carpal tunnel syndrome (CTS) patients have symptoms in both the median and ulnar digits more frequently than in the median digits alone. This is possibly because of close anatomical contiguity of the carpal tunnel and Guyon’s canal, and the high pressure may also affect the latter, causing indirect compression of ulnar nerve fibers. Thus, we ev.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.17.17
DOI:
http://dx.doi.org/10.4238/2015.April.17.17
Medical Genetics   Research Article

Genome-wide pathway analysis in amyotrophic lateral sclerosis

Authors: Y.H. Lee and G.G. Song

The aims of this study were to identify candidate singlenucleotide polymorphisms (SNPs) and mechanisms of amyotrophic lateral sclerosis (ALS) and to generate SNP-to-gene-to-pathway hypotheses. An ALS genome-wide association study (GWAS) dataset that included 483,051 SNPs in 276 patients with ALS and 271 controls of European descent was used in this study... Read More»

Genet. Mol. Res. 14(2):
2015.June.11.19
DOI:
10.4238/2015.June.11.19
Human Genetics   Research Article

Rapid sedation induced by fentanyl combined with propofol via an intrathecal chemotherapy injection for leukemia in children

Authors: X. Tian,Y.-H. Yang,H.-Y. Wei,J.-Q. Lao,H.-P. Wang and Y.-Y. Tian

This study explored the sedative and analgesic effects of fentanyl combined with propofol via an intrathecal chemotherapy injection for acute leukemia (acute lymphocytic leukemia or acute myelocytic leukemia) among children, to relieve pain and difficulty during intrathecal injection, improve treatment compliance, increase the success rate of single punct.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.17.18
DOI:
http://dx.doi.org/10.4238/2015.April.17.18
Human Genetics   Research Article

Association between IL-10-G1082A polymorphisms and the development of coronary artery disease in a Chinese population

Authors: K. Liang, S.R. Dong and H. Peng

We conducted a case-control study to investigate the association between IL-10-G1082A (rs1800896) polymorphism and the development of coronary artery disease (CAD) in the Chinese population. We recruited 295 CAD patients and 355 healthy controls from the Fifth Affiliated Hospital of Zhengzhou University between April 2012 and .. Read More»

Genet. Mol. Res. 15(2):
gmr.15027933
DOI:
10.4238/gmr.15027933
Microbial Genetics   Research Article

Characterization of Aspergillus niger ndo-1,4-�²-glucanase ENG1 secreted from Saccharomyces cerevisiae using different expression vectors

Authors: S.M. Taipakova, I.T. Smekenov, M.K. Saparbaev and A.K. Bissenbaev

Heterologous expression of Aspergillus niger endo-1,4- β-glucanase (ENG1) in Saccharomyces cerevisiae was tested both with an episomal plasmid vector (YEGAp/eng1) and a yeast vector capable of integration into the HO locus of the S. cerevisiae chromosome (pHOGAPDH-eng1-KanMX4-HO). In both cases, eng1 gene expression in yeast, with its native signal s.. Read More»

Genet. Mol. Res. 14(2):
2015.June.11.20
DOI:
10.4238/2015.June.11.20
Plant Genetics   Research Article

Assessment of apple core collections constructed using phenotypic and genotypic data

Authors: W.H. Yun, S.H. Ban, G.H. Kim, J.-H. Kim, S.I. Kwon and C. Choi

Several types of information can be used to select core collections, including passport data, agronomic data, and molecular data. However, little is known about the ability of core collections to retain the genetic diversity and structure of the whole collection for characters that were not considered during the selection, particularly when molecular mark.. Read More»

Genet. Mol. Res. 14(2):
2015.June.11.21
DOI:
10.4238/2015.June.11.21
Medical Genetics   Short communication

Polymorphisms in GSTM1, GSTT1, GSTP1, and GSTM3 genes and breast cancer risk in northeastern Mexico

Authors: G. Jaramillo-Rangel, M. Ortega-Mart�­nez, R.M. Cerda-Flores andH.A. Barrera-Salda�±a

Glutathione S-transferases (GSTs) are a family of phase II metabolizing enzymes involved in carcinogen detoxification and the metabolism of various bioactive compounds. Several genes that code for these enzymes are polymorphic in an ethnicity-dependent manner, with particular genotypes previously associated with an increased risk of breast cancer. The pur.. Read More»

Genet. Mol. Res. 14(2):
2015.June.11.22
DOI:
10.4238/2015.June.11.22
Microbial Genetics   Research Article

Genetic variability in isolates of Chromobacterium violaceum from pulmonary secretion, water, and soil

Authors: A.C. Santini, J.T. Magalh�£es, J.C.M. Cascardoâ�  and R.X. Corr�ªa

Chromobacterium violaceum is a free-living Gram-negative bacillus usually found in the water and soil in tropical regions, which causes infections in humans. Chromobacteriosis is characterized by rapid dissemination and high mortality. The aim of this study was to detect the genetic variability among C. violaceum type strain A.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027955
DOI:
10.4238/gmr.15027955
Plant Genetics   Research Article

Population genetic structure of Attalea vitrivir Zona (Arecaceae) in fragmented areas of southeast Brazil

Authors: R.R.M. Santos, M.M. Cavallari, M.A.S. Pimenta, A.G. Abreu, M.R. Costa and M.L. Guedes

Attalea vitrivir Zona (synonym Orbignya oleifera) is one of the six species of Arecaceae known as “babassu”. This species is used to make cosmetics, food, and detergents due to the high concentration of oil in the seeds. It is found only in fragmented areas of southern Bahia State and northern Minas Gerais State, southeast Brazil, and this fra.. Read More»

Genet. Mol. Res. 14(2):
2015.June.11.23
DOI:
10.4238/2015.June.11.23
Human Genetics   Research Article

Simultaneous selection for cowpea (Vigna unguiculata L.) genotypes with adaptability and yield stability using mixed models

Authors: F.E. Torres, P.E. Teodoro, E.V. Rodrigues, A. Santos, A.M. Corr�ªa, G. Ceccon

The aim of this study was to select erect cowpea (Vigna unguiculata L.) genotypes simultaneously for high adaptability, stability, and yield grain in Mato Grosso do Sul, Brazil using mixed models. We conducted six trials of different cowpea genotypes in 2005 and 2006 in Aquidauana, Chapadão do Sul, Dourados, and Primave.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028272
DOI:
10.4238/gmr.15028272