Novel genomic microsatellite markers for genetic population and diversity studies of tropical scalloped spiny lobster (Panulirus homarus) and their potential application in related Panulirus species
Authors: M. Delghandi, S. Goddard, D.R. Jerry, H.T. Dao, M.S.N. Al Hinai, W. Al-Amry and A. Al-Marzouqi
Fourteen polymorphic microsatellites with perfect di-, tri-, and tetra-nucleotide repeats were identified for Panulirus homarus using Roche 454 whole-genome sequencing method. Microsatellites were efficiently co-amplified in four multiplexes and a singleplex, providing consistent and easily interpretable genotypes. The number .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027846
- DOI:
- 10.4238/gmr.15027846
Effect of Ginkgo biloba extract on apoptosis of brain tissues in rats with acute cerebral infarction and related gene expression
Authors: C. Wu, X. Zhao, X. Zhang, S. Liu, H. Zhao and Y. Chen
We investigated the effect of Ginkgo biloba extract on apoptosis of brain tissues in rats with acute cerebral infarction and apoptosis-related gene expression. Rat models of acute cerebral infarction were constructed using the suture method, and randomly divided into the control group, model, and treatment groups. In the treatment group, 4 mg/kg G. biloba.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.11.14
- DOI:
- 10.4238/2015.June.11.14
Repair of large segmental bone defects in rabbits using BMP and FGF composite xenogeneic bone
Authors: X. Li, Z. Lin, Y. Duan, X. Shu, A. Jin, S. Min and W. Yi
The objective of this study was to determine the ability of bone morphogenetic protein (BMP) and fibroblast growth factor (FGF) to repair large segmental radial bone defects in rabbits. We treated calf cancellous bones with 3 mg/L BMP (Group A), 5 μg/L FGF (Group B), or 3 mg/L BMP plus 5 μg/L FGF (Group C). A bone damage model was established using .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.11.15
- DOI:
- 10.4238/2015.June.11.15
Effects of exogenous 5-aminolevulinic acid on photosynthesis, stomatal conductance, transpiration rate, and PIP gene expression of tomato seedlings subject to salinity stress
Authors: Y.Y. Zhao, F. Yan, L.P. Hu, X.T. Zhou, Z.R. Zou and L.R. Cui
The effects of exogenous 5-aminolevulinic acid (ALA) on photosynthesis, plant growth, and the expression of two aquaporin genes in tomato seedlings under control and salinity conditions were investigated. Exogenous ALA application significantly improved net photosynthetic rate (Pn ), total chlorophyll content, and plant biomass accumulation of tomato seed.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.11.16
- DOI:
- 10.4238/2015.June.11.16
DNMT3A -448A>G polymorphism and cancer risk: a meta-analysis
Authors: C.H. Liu,T. Tao1,L. Jiang1,B. Xu,L. Zhang, K. Lu,X.W. Zhang,S.Q. Chen,D.C. Liu and M. Chen
Cancer is a major public health problem worldwide that involves complex processes and factors. For instance, methylation is important in tumorigenesis. DNA (cytosine-5)-methyltransferase 3A (DNMT3A) is the main de novo methyltransferase implicated in this process. In DNMT3A, the -448A>G polymorphism is associated with cancer; however, the results of va.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.17.14
- DOI:
- http://dx.doi.org/10.4238/2015.April.17.14
Inhibition of human chronic myelogenous leukemia K562 cell growth following combination treatment with resveratrol and imatinib mesylate
Authors: X.J. Wang and Y.H. Li
To investigate the effect of treatment with resveratrol combined with imatinib mesylate on human chronic myelogenous leukemia K562 cell growth inhibition and apoptosis, in vitro cultured human chronic myelogenous leukemia K562 cells were incubated with different concentrations of resveratrol and imatinib mesylate when the cells were in the logarithmic pha.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.11.17
- DOI:
- 10.4238/2015.June.11.17
Identification of CD14 transcript in blood polymorphonuclear neutrophil leukocytes and functional variation in Holsteins
Authors: J.M. Huang, X.G. Wang, Q. Jiang, Y. Sun, C.H. Yang, Z.H. Ju,H.S. Hao, C.F. Wang, J.F. Zhong and H.B. Zhu
Polymorphonuclear neutrophil (PMN) leukocytes are primary phagocytic cells of the bovine mammary gland and a first line of defense against invading pathogens during bovine mastitis infection. Cluster of differentiation 14 (CD14) is mainly expressed in macrophages and neutrophils and acts as a co-receptor that binds bacterial l.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027932
- DOI:
- 10.4238/gmr.15027932
Effects of silver nanoparticles and gold nanoparticles on IL-2, IL-6, and TNF-�± production via MAPK pathway in leukemic cell lines
Authors: C. Parnsamut and S. Brimson
Silver nanopaticles (AgNPs) and gold nanoparticles (AuNPs) have various applications in medical healthcare and various biological properties such as anti-inflammation, anti-cancer, and anti-angiogenesis. In this study, we investigated the effect of AgNPs and AuNPs on cytokine production via the mitogen-activated protein kinase pathway in leukemic cell lin.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.17.15
- DOI:
- http://dx.doi.org/10.4238/2015.April.17.15
Novel polymorphisms of the PRKAG2 gene and their association with body measurement and meat quality traits in Qinchuan cattle
Authors: C.Z. Fu,W.Q. Tian,Y.K. Li,S.J. Wei,G. Cheng,H.B. Wang and L.S. Zan
Body measurement and meat quality traits play important roles in the evaluation of productivity and economy in cattle, which are influenced by genes and environmental factors. PRKAG2, which encodes the γ2 regulatory subunit of AMPK, is associated with key metabolic pathways in muscle. We detected bovine PRKAG2 gene polymorphisms and analyzed their a.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.17.16
- DOI:
- http://dx.doi.org/10.4238/2015.April.17.16
Identification and characterization of novel NBS-LRR resistance gene analogues from the pea
Authors: S. Djebbi, D. Bouktila, H. Makni, M. Makni and M. Mezghani-Khemakhem1
Pea (Pisum sativum) is one of the most cultivated legumes in the world, and its yield and seed quality are affected by a variety of pathogens. In plants, NBS-LRR (nucleotide binding siteleucine-rich repeat) is the main class of disease resistance genes. Using degenerate primers deduced from conserved motifs in the NBS domain of known resistance genes, we .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.11.18
- DOI:
- 10.4238/2015.June.11.18