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Human Genetics   Research Article

Sperm quality and DNA damage in men from Jilin Province, China, who are occupationally exposed to ionizing radiation

Authors: D.D. Zhou, J.L. Hao, K.M. Guo, C.W. Lu and X.D. Liu

Long-term radiation exposure affects human health. Ionizing radiation has long been known to raise the risk of cancer. In addition to high doses of radiation, low-dose ionizing radiation might increase the risk of cardiovascular disease, lens opacity, and some other non-cancerous diseases. Low- and high-dose exposures to ioniz.. Read More»

Genet. Mol. Res. 15(1):
gmr.15018078
DOI:
10.4238/gmr.15018078
Cytogenomics   Research Article

Lignocellulolytic enzymes and bacteria associated with the digestive tracts of Stenochironomus (Diptera: Chironomidae) larvae

Authors: R. Koroiva, C.W.O. Souza, D. Toyama, F. Henrique-Silva and A.A. Fonseca-Gessner

We analyzed the digestive activity of the enzymes that digest cellulose and hemicellulose and the bacterial community that is capable of hydrolyzing wood compounds in the digestive tracts of Stenochironomus (Diptera: Chironomidae) larvae, which are miners of decomposing submerged tree and bush branches. Based on quantification of reducing sugars, these la.. Read More»

Genet. Mol. Res. 12(3):
2013.April.2.2
DOI:
10.4238/2013.April.2.2
Cytogenomics   Research Article

Gene expression patterns of invertase gene families and modulation of the inhibitor gene in tomato sucrose metabolism

Authors: Y.L. Zhang, A.H. Zhang and J. Jiang

Patterns of gene expression in the different types of sucrose metabolism in the tomato are highly variable and heritable. This genetic variation causes considerable functional differences. We examined the patterns of expression of invertase (Inv) gene families and an invertase inhibitor (INH) gene involved in elongating roots, hypocotyls, and fruit of the.. Read More»

Genet. Mol. Res. 12(3):
2013.January.24.1
DOI:
10.4238/2013.January.24.1
Medical Genetics   Research Article

Reply to commentary by G. Sikri and S. Dua on the article â??Correlation between single nucleotide polymorphisms in hypoxia-related genes and susceptibility to acute high-altitude pulmonary edemaâ? published in Genetics and Molecular Research 14 (3): 11562-11572 to the letter published in Genet. Mol. Res. 14 (4): 15904-15905

Authors: L.J. Wu

The object in this study was a Han Chinese population in Lhasa, with 3658 m in altitude from Chengdu, which has 505 m in altitude by air. Within 24 to 48 h before the subjects arrived in the plateau, they completed a basic situation questionnaire, under the guidance of medical staff. Within 24 to 48 h after they reached the plateau, the subjects completed.. Read More»

Genet. Mol. Res. 15(1):
gmr.15016155
DOI:
10.4238/gmr.15016155
Cytogenomics   Research Article

Effect of atorvastatin on left atrial function of patients with paroxysmal atrial fibrillation

Authors: Y.D. Li, B.P. Tang, F. Guo, J.X. Li, W. Han, Q. Tang and Y.Y. Zhang

The aim of this study was to evaluate the effects of atorvastatin on left atrial (LA) function in paroxysmal atrial fibrillation patients. Fifty-eight paroxysmal atrial fibrillation patients were divided into two groups (treatment and control groups). The echocardiography parameters, including LA active emptying volume (LAAEV), LA active emptying fraction.. Read More»

Genet. Mol. Res. 12(3):
2013.September.10.5
DOI:
10.4238/2013.September.10.5
Cytogenomics   Research Article

Odorant receptor genes are expressed in olfactory neuroblastoma

Authors: D.C. Gonzalez-Kristeller, L.M. Gutiyama, A.H. Campos, F.A. Soares, H. Brentani and B. Malnic

Olfactory neuroblastoma (ONB) is a malignant tumor found in the human nasal cavity. These tumors are rare and poorly characterized at the molecular level. In this study, we asked whether olfactory-specific genes are expressed in ONBs by using reverse-transcriptase-polymerase chain reaction. We found that the olfactory marker protein and the RIC-8B genes, .. Read More»

Genet. Mol. Res. 12(3):
2013.September.10.4
DOI:
10.4238/2013.September.10.4
Cytogenomics   Research Article

Fourteen years after the Shahid-Rajaei dam construction: an evaluation of morphometric and genetic differentiation between isolated up- and downstream populations of Capoeta capoeta gracilis (Pisces: Cyprinidae) in the Tajan River of Iran

Authors: Hossein AnvariFar, H. Farahmand, D.M. Silva, R.P. Bastos, A. Khyabani and Hassan AnvariFar

We evaluated the effects of the Shahid-Rajaei dam, 14 years after its construction, on morphometric and genetic divergence between up- and downstream populations of the Iranian fish Siah-Mahi (Capoeta capoeta gracilis). Sixty-six specimens were analyzed. There were significant differences between the 2 groups in the means of 16 morphometric characters (un.. Read More»

Genet. Mol. Res. 12(3):
2013.September.10.3
DOI:
10.4238/2013.September.10.3
Bioinformatics   Research Article

Association between the TRAIL single nucleotide polymorphism rs1131580 and type 2 diabetes mellitus in a Han Chinese population

Authors: M.Y. Yu, P.Q. Zhao, X.H. Yan, B. Liu, Q.Q. Zhang, R. Wang, C.H. Ma, X.H. Liang, F.L. Zhu and L.F. Gao

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is expressed in different tissues and cells, including the pancreas and lymphocytes, and it can selectively induce apoptosis in tumor cells but not in most normal cells. TRAIL plays critical roles in type 1 diabetes mellitus, and is involved in type 2 diabetes mellitus (T2DM). We recent.. Read More»

Genet. Mol. Res. 12(3):
2013.September.10.2
DOI:
10.4238/2013.September.10.2
Cytogenomics   Research Article

Genetic variability in Melipona scutellaris from Rec?´ncavo, Bahia, Brazil

Authors: J.L. Viana, A.K. Francisco, C.A.L. Carvalho and A.M. Waldschmidt

Bees play a key role in pollination and thereby help maintain plant diversity. The stingless bee Melipona scutellaris is an important pollinator in northeastern Brazil because it is endemic to this region. Both deforestation and timber harvesting have reduced the nesting sites for this species, thus reducing its population and range. Genetic studies may h.. Read More»

Genet. Mol. Res. 12(3):
2013.September.10.1
DOI:
10.4238/2013.September.10.1
Microbial Genetics   Research Article

Molecular cloning and functional analysis of MRLC2 in Tianfu, Boer, and Chengdu Ma goats

Authors: H.G. Xu, G.Y. Xu, L. Wan and J. Ma

To determine the molecular basis of heterosis in goats, fluorescence quantitative polymerase chain reaction (PCR) was performed to investigate myosin-regulatory light chain 2 (MRLC2) gene expression in the longissimus dorsi muscle tissues of the Tianfu goat and its parents, the Boer and Chengdu Ma goats. The goat MRLC2 gene was differentially expressed in.. Read More»

Genet. Mol. Res. 12(3):
2013.March.15.7
DOI:
10.4238/2013.March.15.7