Relationship between the expression of Notch1 and EZH2 and the prognosis of breast invasive ductal carcinoma
Authors: L. Zhao, Q.Y. Zhang, X. Luan, X. Huang, S. Zhao and H. Zhao
We determined whether the coexpression of Notch1 and EZH2 influences the progression and prognosis of breast invasive ductal carcinoma. Using the c2 test, a significant difference was found between high and low expression of Notch1 in terms of lymph node, hormone receptor, and p53 expression (P < 0.05). Moreover, a signific.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017464
- DOI:
- 10.4238/gmr.15017464
Rapamycin enhances IFN-�³ and IL-4 production in co-culture of g�´ T and dendritic cells from mice with lipopolysaccharide-induced acute lung injury
Authors: X.L. Chen, J. Li, G.G. Xu, H.X. Li and J. Guo
This study aimed to study the role of rapamycin (RAPA) in modulating the interaction between gδ T cells and dendritic cells (DCs) in a lipopolysaccharide (LPS)-induced acute lung injury mouse model. Mice were injected with LPS to establish the acute lung injury model or LPS + RAPA to assess the role of RAPA in modulating.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027511
- DOI:
- 10.4238/gmr.15027511
Simple-sequence repeat markers of Cattleya coccinea (Orchidaceae), an endangered species of the Brazilian Atlantic Forest
Authors: M. Novello, J.F. Rodrigues, F. Pinheiro, G.C.X. Oliveira, E.A. Veasey and S. Koehler
Microsatellite markers were developed for the endangered Brazilian orchid species Cattleya coccinea to describe its genetic diversity and structure and to support conservation studies. Nine microsatellite loci were isolated and characterized using an enriched genomic library. All loci are polymorphic at least in the 2 populations sampled, except for loci .. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.3.3
- DOI:
- 10.4238/2013.September.3.3
Association between the pre-miR-196a2 rs11614913 polymorphism and gastric cancer susceptibility in a Chinese population
Authors: M. Li, R.J. Li, H. Bai, P. Xiao, G.J. Liu, Y.W. Guo and J.Z. Mei
We did a case-control study to provide a more comprehensive evaluation of the association of the pre-miR-196a2 rs11614913 polymorphism with gastric cancer. Between January 2013 and December 2014, 182 patients newly diagnosed with primary gastric cancer and 182 control subjects were recruited at Zhengzhou People’s Hospita.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027516
- DOI:
- 10.4238/gmr.15027516
A fast and simple method for the polymerase chain reaction-based sexing of livestock embryos
Authors: K.C.S. Tavares, I.S. Carneiro, D.B. Rios, C. Feltrin, A.K.C. Ribeiro, S. Gaud�ªncio-Neto, L.T. Martins, L.H. Aguiar, C.R. Lazzarotto, C.E.M. Calder�³n, F.E.M. Lopes, L.P.R. Teixeira, M. Bertolini and L.R. Bertolini
Embryo sexing is a powerful tool for livestock producers because it allows them to manage their breeding stocks more effectively. However, the cost of supplies and reagents, and the need for trained professionals to biopsy embryos by micromanipulation restrict the worldwide use of the technology to a limited number of speciali.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017476
- DOI:
- 10.4238/gmr.15017476
Transcriptome network-based method to identify genes associated with unruptured intracranial aneurysms
Authors: L. Wei, Y.J. Gao, S.P. Wei, Y.F. Zhang, W.F. Zhang, J.X. Jiang, Z.Y. Sun and W. Xu
Intracranial aneurysm is a balloon or sac-like dilatation of blood vessels inside the brain. Despite their importance, the biological mechanisms of intracranial aneurysms are not totally understood. We used public genome-wide gene expression profile data to identify potential genes that are involved in intracranial aneurysm in order to construct a regulat.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.3.2
- DOI:
- 10.4238/2013.September.3.2
Isolation and characterization of novel microsatellites for Abies koreana and A. nephrolepis (Pinaceae)
Authors: J.K. Hong, J. Lim, B.Y. Lee and M. Kwak
Abies koreana is an endemic and rare species from Korea and is classified as endangered by the International Union for Conservation of Nature. Although the genetic diversity assessment for current population of A. koreana needs to be performed urgently, no microsatellite markers have been developed for this species. In the pre.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027542
- DOI:
- 10.4238/gmr.15027542
Positional effects of polymorphisms in probe-target sequences on genoplot images of oligonucleotide microarrays
Authors: T.L. Cui, H. Nakaoka, K. Akiyama, H. Kamura, K. Hosomichi, J. Bae, H. Cheong, H. Shin, T. Yada and I. Inoue
Single nucleotide polymorphisms (SNPs) present in probetarget sequences (SPTS) have been shown to be associated with abnormal genoplot images. We explored the effects of SPTS positions on genoplot images using a data set from a genome-wide association study typed on an Illumina Human Hap300 platform. We screened the physical g.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr737
- DOI:
- 10.4238/vol9-1gmr737
Complete mitochondrial genomes reveal phylogeny relationship and evolutionary history of the family Felidae
Authors: W.Q. Zhang and M.H. Zhang
Many mitochondrial DNA sequences are used to estimate phylogenetic relationships among animal taxa and perform molecular phylogenetic evolution analysis. With the continuous development of sequencing technology, numerous mitochondrial sequences have been released in public databases, especially complete mitochondrial DNA sequences. Using multiple sequence.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.3.1
- DOI:
- 10.4238/2013.September.3.1
Genetic relationships between Lolium (Poaceae) species revealed by RAPD markers
Authors: X. Ma, X.-Y. Gu, T.-T. Chen, S.-Y. Chen, L.-K. Huang and X.-Q. Zhang
The genus Lolium is one of the most important groupings of temperate forage grasses, including about eight recognized species that are native to some temperate and subtropical regions of the northern hemisphere. We examined genetic relationships among 18 accessions representing all Lolium species using RAPD markers. Among 50 random primers that we screene.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.March.11.4
- DOI:
- 10.4238/2013.March.11.4