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Medical Genetics   Research Article

Investigation of NQO1 genetic polymorphism, NQO1 gene expression and PAH-DNA adducts in ESCC. A case-control study from Iran

Authors: H.A. Marjani, F. Biramijamal, N. Rakhshani, A. Hossein-Nezhad and R. Malekzadeh

We evaluated the effect of NQO1 genetic variation on PAH-DNA adducts in esophageal squamous cell carcinoma (ESCC) in northeast Iran. Golestan Province in northeast of Iran has one of the highest esophageal cancer incidences in the world. The study included 93 ESCC cases and 50 control individuals who were seen at the clinical .. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr693
DOI:
10.4238/vol9-1gmr693
Microbial Genetics   Research Article

Mitotic crossing-over induced by two commercial herbicides in diploid strains of the fungus Aspergillus nidulans

Authors: R.A. Cardoso, L.T.A. Pires, T.D. Zucchi, F.D. Zucchi and T.M.A.D. Zucchi

Some herbicides are suspected of promoting teratogenic, carcinogenic and mutagenic events. Detection of induced mitotic crossing-over has proven to be an indirect way of testing the carcinogenic properties of suspicious substances, because mitotic crossing-over is involved in the multistep process of carcinogenesis. We examine.. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr688
DOI:
10.4238/vol9-1gmr688
Plant Genetics   Research Article

Gelling agents and culture vessels affect in vitro multiplication of banana plantlets

Authors: Y.A. Ka�§ar, B. Bi�§en, �°. Varol, Y.Y. Mendi, S. Ser�§e and S. ��etiner

Agar is the most commonly used gelling agent in media for plant tissue culture. Because of the high price of tissue-culture-grade agar, attempts have been made to identify suitable alternatives. The type of culture vessel and lid also affects the gaseous composition inside the vessel as well as light penetration. In turn, the .. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr744
DOI:
10.4238/vol9-1gmr744
Bioinformatics   Research Article

Identifying the molecular basis of functions in the transcriptome of the social amoeba Dictyostelium discoideum

Authors: T.J. Whitney, D.G. Gardner, M.L. Mott and M. Brandon

The unusual life cycle of Dictyostelium discoideum, in which an extra-cellular stressor such as starvation induces the development of a multicellular fruiting body consisting of stalk cells and spores from a culture of identical amoebae, provides an excellent model for investigating the molecular control of differentiation and.. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr752
DOI:
10.4238/vol9-1gmr752
Plant Genetics   Research Article

Optimization of DNA extraction from seeds and fresh leaf tissues of wild marigold (Tagetes minuta) for polymerase chain reaction analysis

Authors: I. Shahzadi, R. Ahmed, A. Hassan and M.M. Shah

Tagetes, a genus of flowering marigolds in the family Asteraceae (Compositeae), is reported to be a medicinal plant with hypotensive, spasmolytic, anti-inflammatory, antimicrobial, and antifungal properties. Tagetes minuta characteristically contains high concentrations of essential oils, flavonoids, polyphenols, and polysacch.. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr747
DOI:
10.4238/vol9-1gmr747
Human Genetics   Abstracts

Biochemical and molecular studies of copper metabolism during the infection process of the human pathogenic fungus Paracoccidioides brasiliensis

Authors: R.S. Santos

Genet. Mol. Res. 9(1):
vol9-1TA028
DOI:
10.4238/vol9-1TA028
Animal Genetics   Research Article

Karyotypic evolution trends in Rhamdia quelen (Siluriformes, Heptapteridae) with considerations about the origin and differentiation of its supernumerary chromosomes

Authors: C. Garcia, C. Oliveira and L.F. Almeida-Toledo

Among catfish species of the genus Rhamdia reported for the Brazilian territory, R. quelen is the most widespread, being found in nearly all hydrographic basins of Brazil. Nowadays, R. quelen is a synonym for at least 47 other species in this genus, its taxonomic status still being controversial. The available cytogenetic repo.. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr750
DOI:
10.4238/vol9-1gmr750
Human Genetics   Supplements

Benefits of kinesiotherapy and aquatic rehabilitation on sickle cell anemia. A case report

Authors: G. Tinti, R. Somera Jr., F.M. Valente and C.R.B. Domingos

The process of hemoglobin polymerization and the consequent sickling of red blood cells that occurs in patients with sickle cell disease shortens the half-life of red blood cells. It causes vaso-occlusive complications, as well as pain and pulmonary and cardiovascular dysfunction. We evaluated an aquatic rehabilitation program.. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr722
DOI:
10.4238/vol9-1gmr722
Plant Genetics   Research Article

Molecular cloning and characterization of a chlorophyll degradation regulatory gene (ZjSGR) from Zoysia japonica

Authors: K. Teng, Z.H. Chang, G.Z. Xiao, W.E. Guo, L.X. Xu, Y.H. Chao and L.B. Han

The stay-green gene (SGR) is a key regulatory factor for chlorophyll degradation and senescence. However, to date, little is known about SGR in Zoysia japonica. In this study, ZjSGR was cloned, using rapid amplification of cDNA ends-polymerase chain reaction (PCR). The target sequence is 831 bp in length, corresponding to 276 .. Read More»

Genet. Mol. Res. 15(2):
gmr.15028176
DOI:
10.4238/gmr.15028176
Bioinformatics   Research Article

Overexpression of type-A rice response regulators, OsRR3 and OsRR5, results in lower sensitivity to cytokinins

Authors: X. Cheng*, H. Jiang*, J. Zhang, Y. Qian, S. Zhu and B. Cheng

Response regulators are part of a two-component regulatory system. The type-A Arabidopsis response regulators act as negative regulators. To understand the function of type-A response regulators in the model monocot plant, rice (Japonica cultivar-group: Zhonghua11), we overexpressed two type-A OsRR genes, OsRR3 and OsRR5 (pACT.. Read More»

Genet. Mol. Res. 9(1):
vol9-1gmr739
DOI:
10.4238/vol9-1gmr739