Genetic potential of common bean progenies obtained by different breeding methods evaluated in various environments
Authors: V.A. Pontes J�ºnior, P.G.S. Melo, H.S. Pereira and L.C. Melo
Grain yield is strongly influenced by the environment, has polygenic and complex inheritance, and is a key trait in the selection and recommendation of cultivars. Breeding programs should efficiently explore the genetic variability resulting from crosses by selecting the most appropriate method for breeding in segregating popu.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038622
- DOI:
- 10.4238/gmr.15038622
The kinin B2 receptor gene structure, product processing and expression in adult and fetal rats: evidence for gene evolution
Authors: C.E. Fran�§a, C.F. Vicari, A.M. Piza, E.A. Geroldo, M.L. Be�§ak, W. Be�§ak, R.C. Stocco and C.J. Lindsey
We examined the structure of the rat kinin B2 receptor gene (KB2r) and encoding messenger RNA (mRNA) processing. Differently from the closely related mouse and rabbit genes that have three exons and two introns, the rat gene purportedly consists of four exons and three introns. There are two purported gene products; one of the.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr681
- DOI:
- 10.4238/vol9-1gmr681
Temporal variations of Hsp60 and HSF-1 in primary rat myocardial cells in vitro under heat stress
Authors: R. Buriro, Y.J. Lv, I. Ali, S. Tang, Z.J. Liu, M. Zhang, A. Adem, J. Hartung and E.D. Bao
The mechanisms involved in sudden animal death due to acute heart failure during heat stress are not well understood. We examined the relationship between heat stress-induced variations of protective Hsp60 and expression of its regulatory factor, HSF-1, in heat-stressed primary myocardial cells of neonatal rats in vitro through cardiac enzyme detection, i.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.August.20.2
- DOI:
- 10.4238/2013.August.20.2
Geometry applied to breeding common beans (Phaseolus vulgaris)
Authors: J.G. Lima and M.A.P. Ramalho
The primary components of common bean (Phaseolus vulgaris) grain yield (W) are the number of pods (X), the number of grains per pod (Y), and the weight of the grains (Z). In 1964, Grafius suggested using geometry in plant breeding; W corresponds to the volume of a parallelepiped with three axes, X, Y, and Z. Because the cube i.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027873
- DOI:
- 10.4238/gmr.15027873
Increased miR-155-5p expression in dermal mesenchymal stem cells of psoriatic patients: comparing the microRNA expression profile by microarray
Authors: R.X. Hou, R.F. Liu, X.C. Zhao, Y.R. Jia, P. An, Z.P. Hao, J.Q. Li, X.H. Li, G.H. Yin and K.M. Zhang
Mesenchymal stem cells (MSCs) have pleiotropic immuno-modulatory effects and pro-angiogenic ability, leading to the presumption that MSCs may be involved in the pathogenesis of many inflammatory or autoimmune disorders, including psoriasis. In a previous study, we reported the specific gene expression profile ofdermal MSCs fro.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038631
- DOI:
- 10.4238/gmr.15038631
Association between the -1438A/G polymorphism of the serotonin 2A receptor gene and late-onset psoriasis in a Thai population
Authors: C. Ronpirin, T. Tencomnao and J. Wongpiyabovorn
Expression of serotonin 2A receptor (5-HTR2A) is known to increase in psoriasis, a chronic inflammatory skin disease. We investigated a possible association between the -1438A/G single nucleotide polymorphism (rs6311) in the promoter region of 5-HTR2A gene and psoriasis in a Thai population. One hundred and twelve psoriatic pa.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr718
- DOI:
- 10.4238/vol9-1gmr718
Meta-analysis of association of common variants in the KCNJ11-ABCC8 region with type 2 diabetes
Authors: L.J. Qin, Y. Lv and Q.Y. Huang
KCNJ11 (potassium inwardly rectifying channel, subfamily J, member 11) and ABCC8 (ATP-binding cassette, subfamily C (CFTR/MRP), member 8) have been studied for association with type 2 diabetes in various ethnic populations with contradictory results. We performed a comprehensive meta-analysis for KCNJ11 rs5219, rs5210, rs5215, and ABCC8 rs757110 to evalua.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.August.20.1
- DOI:
- 10.4238/2013.August.20.1
Bioinformatic and expression analysis of the OMT gene family in Pyrus bretschneideri cv. Dangshan Su
Authors: X. Cheng, Y. Xiong, D.H. Li, J. Cheng, Y.P. Cao, C.C. Yan, Q. Jin, N. Sun, Y.P. Cai and Y. Lin
With high nutritional value in its fruits, Dangshan Su pear has been widely cultivated in China. The stone cell content in fruits is a key factor affecting fruit quality in pear, and the formation of stone cells has been associated with lignin biosynthesis. O-Methyltransferase (OMT) is a key enzyme involved in lignin metabolism within the phenylpropanoid .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038664
- DOI:
- 10.4238/gmr.15038664
Genetic relationship between the Nordestino horse and national and international horse breeds
Authors: D.A.F. Pires, E.G.A. Coelho, J.B. Melo, D.A.A. Oliveira, M.N. Ribeiro, E. Gus Cothran and R. Juras
Knowledge of genetic diversity and relationships between breeds is very important for conservation programs. Hair samples were collected from 393 individual Nordestino horses and genotyped using 14 microsatellite markers in order to investigate the genetic relationship between this breed and 66 international horse breeds. Ther.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027881
- DOI:
- 10.4238/gmr.15027881
Chicken skeletal muscle-associated macroarray for gene discovery
Authors: E.C. Jorge, C.M.R. Melo, M.F. Ros�¡rio, J.R.S. Rossi, M.C. Ledur, A.S.A.M.T. Moura and L.L. Coutinho
Macro- and microarrays are well-established technologies to determine gene functions through repeated measurements of transcript abundance. We constructed a chicken skeletal muscle-associated array based on a muscle-specific EST database, which was used to generate a tissue expression dataset of ~4500 chicken genes across 5 ad.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr712
- DOI:
- 10.4238/vol9-1gmr712