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Plant Genetics   Research Article

Optimization of a biolistic transformation system for transfer of antifreeze gene KN2 and the bar herbicide resistance gene in common wheat

Authors: L. Cai, D.F. Sun and G.L. Sun

We studied the effects of different media for callus induction and differentiation, and pre-culture period of immature wheat embryo culture on biolistic transformation efficiency for including antifreeze gene KN2 and bar conferring resistance to the herbicide bialaphos. The percentage of plantlets generated from induction and .. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.April.30.8
DOI:
http://dx.doi.org/10.4238/2014.April.30.8
Human Genetics   Research Article

Association of the CYP1A1 MspI and TNF�±-308 polymorphisms with chronic obstructive pulmonary disease in Inner Mongolia

Authors: L. Yang, F. Li2*, M. Yan and X. Su

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by persistent airflow limitation. Smoking, occupational exposures, air pollution, and genetics are all risk factors. In the present study, we detected the cytochrome P4501A1 gene (CYP1A1) MspI polymorphism and the tumor necrosis factor alp.. Read More»

Genet. Mol. Res. 13(2):
2014.April.25.6
DOI:
10.4238/2014.April.25.6
Animal Genetics   Research Article

Cloning and expression analysis of the 37-kDa laminin receptor precursor gene from Hyriopsis cumingii

Authors: X.Z. Chang1, J.L. Li1,2, Z.Y. Bai1 and X.L. Li1

Hyriopsis cumingii is an economically important freshwater pearl mussel with high pearl quality that is endemic in China. Investigation of genes relevant to shell formation is important for increased pearl output. The substances that form mollusk shells are secreted by epithelial cells in the mantle, the proliferation of which influences secretion ability.. Read More»

Genet. Mol. Res. 13(4):
2013.December.2.10
DOI:
10.4238/2013.December.2.10
Human Genetics   Research Article

Expression profiles of variation integration genes in bladder urothelial carcinoma

Authors: J.M. Wang, Y.Q. Wang, Z.L. Gao, J.T. Wu, B.K. Shi and C.C. Yu

Bladder cancer is a common cancer worldwide and its incidence continues to increase. There are approximately 261,000 cases of bladder cancer resulting in 115,000 deaths annually. This study aimed to integrate bladder cancer genome copy number variation information and bladder cancer gene transcription level expression data to .. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.April.30.9
DOI:
http://dx.doi.org/10.4238/2014.April.30.9
Microbial Genetics   Research Article

Efficient production of transgenic melon via Agrobacterium-mediated transformation

Authors: I. Bezirganoglu, S.Y. Hwang, J.F. Shaw and T.J. Fang

Oriental melon (Cucumis melo L. var. makuwa) is an important fruit for human consumption. However, this plant species is one of the most recalcitrant to genetic transformation. The lack of an efficient in vitro system limits the development of a reproducible genetic transformation protocol for Oriental melon. In this study, an.. Read More»

Genet. Mol. Res. 13(2):
2014.April.25.7
DOI:
10.4238/2014.April.25.7
Medical Genetics   Research Article

Bibliometric network analysis of glaucoma

Authors: L.-Y. Dong, M. Yin and X.-L. Kang

Elevated intraocular pressure is recognized as the principal risk factor for development of optic nerve head (ONH) injury. Lamina cribrosa (LC) cells and astrocytes are two types of cells in the ONH. We attempted to identify more target genes and predict their underlying molecular mechanisms. In this study, we performed meta-analysis of the data from two .. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.9.1
DOI:
http://dx.doi.org/10.4238/2014.May.9.1
Medical Genetics   Research Article

Ginsenoside Rh2 promotes nonamyloidgenic cleavage of amyloid precursor protein via a cholesterol-dependent pathway

Authors: J. Qiu, W. Li, S.H. Feng, M. Wang and Z.Y. He

Ginsenoside Rh2 (Rh2) is a ginseng derivative used in Chinese traditional medicine. We investigated whether Rh2 can help prevent Alzheimer’s disease symptoms and examined underlying mechanisms. We injected Rh2 into tg2576 Alzheimer’s disease model mice and looked for behavioral improvement and senile plaque reducti.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.9.2
DOI:
http://dx.doi.org/10.4238/2014.May.9.2
Plant Genetics   Research Article

Evaluation of powdery mildew-resistance of grape germplasm and rapid amplified polymorphic DNA markers associated with the resistant trait in Chinese wild Vitis

Authors: J. Zhang, Y. Zhang, H. Yu1, and Y. Wang

The resistance of wild Vitis germplasm, including Chinese and American wild Vitis and Vitis vinifera cultivars, to powdery mildew (Uncinula necator Burr.) was evaluated for two consecutive years under natural conditions. Most of the Chinese and North American species displayed a resistant phenotype, whereas all of the European.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.May.9.3
DOI:
http://dx.doi.org/10.4238/2014.May.9.3
Plant Genetics   Research Article

Development and cross-species amplification of microsatellite loci for Puccinellia maritima, an important engineer saltmarsh species

Authors: R. Rouger, M. Vallejo-Marin and A.S. Jump

The grass Puccinellia maritima is an important saltmarsh ecosystem engineer exhibiting wide morphological variation, which is partially genetically determined. Nevertheless, nothing is known about its population genetics or how neutral genetic variation is distributed throughout its geographical range. Here, we describe 12 pol.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.April.30.3
DOI:
http://dx.doi.org/10.4238/2014.April.30.3
Medical Genetics   Research Article

Clinical value of surfactant protein-A in serum and sputum for pulmonary tuberculosis diagnosis

Authors: H. Hu, G.L. Teng, L.Z. Gai, Y. Yang and C.J. Zhu

The aim of this study was to explore the diagnostic and differential diagnosis value of surfactant protein-A (SP-A) in the serum and sputum for pulmonary tuberculosis. A total of 101 patients with pulmonary tuberculosis, 85 healthy volunteers, and 30 chronic obstructive pulmonary disease (COPD) patients were divided into pulmonary tuberculosis group, heal.. Read More»

Genet. Mol. Res. 12(4):
2013.October.24.2
DOI:
10.4238/2013.October.24.2