Loss of STAG2 causes aneuploidy in normal human bladder cells
Authors: X. Li, T.W. Zhang, J.L. Tang, P.P. Fa, J.X. Lu, F.M. Qi, Z.M. Cai, C.X. Liu and X.J. Sun
The aim of this study was to determine how the function of human stromal antigen 2 (STAG2) plays an important role in proper chromosome separation. STAG2 mRNA in normal bladder cells and bladder tumor cells was evaluated by RT-PCR. The protein levels of STAG2 in normal bladder cells and bladder tumor cells were determined by western blot. A cell prolifera.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.24
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.24
Protein levels and colony development of Africanized and European honey bees fed natural and artificial diets
Authors: M.M. Morais, A.P. Turcatto, R.A. Pereira, T.M. Francoy, K.R. Guidugli-Lazzarini2, L.S. Gon�§alves, J.M.V. de Almeida, J.D. Ellis and D. De Jong
Pollen substitute diets are a valuable resource for maintaining strong and health honey bee colonies. Specific diets may be useful in one region or country and inadequate or economically unviable in others. We compared two artificial protein diets that had been formulated from locally-available ingredients in Brazil with bee bread and a non-protein sucros.. Read More»
- Genet. Mol. Res. 12(4):
- 2013
- DOI:
- 10.4238/2013
Dynamic alterations of the tongue in obstructive sleep apnea-hypopnea syndrome during sleep: analysis using ultrafast MRI
Authors: Y. Wang, J.P. Mcdonald, Y. Liu, K. Pan, X. Zhang and R. Hu
Patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) were evaluated using ultrafast magnetic resonance imaging (UMRI) while asleep and awake to analyze tongue changes. The upper airway of 21 OSAHS patients and 20 normal controls were examined during sleep using UMRI. A series of midline sagittal images of the upper .. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.June.17.7
- DOI:
- http://dx.doi.org/10.4238/2014.June.17.7
Simulating the selfing and migration of Luehea divaricata populations in the Pampa biome to investigate the conservation potential of their genetic resources
Authors: C.M.L. Serrote, L.R.S. Reiniger, V.M. Stefenon, A.R. Curti, L.S. Costa and A.F. Paim
Computer simulations are an important tool for developing conservation strategies for forest species. This study used simulations to investigate the genetic, ecological, and reproductive patterns that contribute to the genetic structure of the tree Lueheadivaricata Mart. & Zucc. in five forest fragments in the Brazilian Pa.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038410
- DOI:
- 10.4238/gmr.15038410
Risk factors for damaged liver function after chemotherapy in hepatitis B virus carriers with non-Hodgkin lymphoma
Authors: X. Li, X.W. Fan, W. Liu, L. Guo, Y. Li, X. Hu, X. Liang,X.P. Ma and S.E. Yang
The goal of this study was to investigate damaged liver function after chemotherapy in hepatitis B virus (HBV) carriers with non-Hodgkin lymphoma (NHL) and to evaluate risk factors associated with a high risk of damaged liver function. Clinical histories of 134 HBV carriers with NHL who were treated with chemotherapy were obtained and analyzed for the occ.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.25
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.25
Toxoplasma gondii: cloning, sequencing, expression, and antigenic characterization of ROP2, GRA5 and GRA7
Authors: M. Igarashi, F. Kano, K. Tamekuni, P.M. Kawasaki, I.T. Navarro,O. Vidotto, M.C. Vidotto, R.Z. Machado and J.L. Garcia
Toxoplasma gondii is an intracellular obligate protozoan,which infects humans and warm-blooded animals. The aim of the present study was to clone the rop2, gra5 and gra7 genes from T. gondii RH strain and to produce recombinant proteins. The rop2, gra5 and gra7 gene fragments produced by polymerase chain reaction were cloned i.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr423
- DOI:
- 10.4238/vol7-2gmr423
Differential expression of E-cadherin gene in human neuroepithelial tumors
Authors: F.J.N. Motta, E.T. Valera, A.K.B. Lucio-Eterovic, R.G.P. Queiroz,L. Neder, C.A. Scrideli, H.R. Machado, C.G. Carlotti-Junior, S.K.N. Marie and L.G. Tone
Cadherins are cell-to-cell adhesion molecules that play an important role in the establishment of adherent-type junctions by mediating calcium-dependent cellular interactions. The CDH1 gene encodes the transmembrane glycoprotein E-cadherin which is important in maintaining homophilic cell-cell adhesion in epithelial tissues. E.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr424
- DOI:
- 10.4238/vol7-2gmr424
Predicting bacterial essential genes using only sequence composition information
Authors: L.W. Ning, H. Lin, H. Ding, J. Huang, N. Rao and F.B. Guo
Essential genes are those genes that are needed by organisms at any time and under any conditions. It is very important for us to identify essential genes from bacterial genomes because of their vital role in synthetic biology and biomedical practices. In this paper, we developed a support vector machine (SVM)-based method to .. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.June.17.8
- DOI:
- http://dx.doi.org/10.4238/2014.June.17.8
Effects of trans-10, cis-12 conjugated linoleic acid on gene expression and lipid metabolism of adipose tissue of growing pigs
Authors: A.A.F.B.V. Jos�©, M.A.S. Gama and D.D.P. Lanna
The objective of the present study was to determine the effects of trans-10, cis-12 conjugated linoleic acid (CLA) in adipose tissue explant cultures of growing pigs on the following responses: lipogenesis (measured as rate of 14C-labeled glucose incorporation over a subsequent 2-h incubation in the presence or absence of insu.. Read More»
- Genet. Mol. Res. 7(2):
- vol7-2gmr417
- DOI:
- 10.4238/vol7-2gmr417
Molecular cloning and expression profile of an ATP-binding cassette (ABC) transporter gene from the hemipteran insect Nilaparvata lugens
Authors: W.J. Zha, S.H. Li, L. Zhou, Z.J. Chen, K. Liu, G.C. Yang, G. Hu, G.C. He and A.Q. You
The ATP-binding cassette (ABC) transporters belong to a large superfamily of proteins that have important physiological functions in all living organisms. In insects, ABC transporters have important functions in the transport of molecules, and are also involved in insecticide resistance, metabolism, and development. In this study, the Nilaparvata lugens S.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.26
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.26