All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Human Genetics   Research Article

Anesthesia treatment in cases of infant epiglottis cyst emergency extirpation operations

Authors: Q. Xu, J.P. Xu and L.Z. Wang

Congenital epiglottic cyst is a rare embryonic disease. As a congenital laryngeal mucocele, its clinical manifestations include repeated sudden dyspneic respiration and even suffocation accompanied by laryngeal stridor after birth. During food intake, bucking and vomiting is a key feature. Delay in diagnosis and treatment of t.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.June.17.4
DOI:
http://dx.doi.org/10.4238/2014.June.17.4
Animal Genetics   Research Article

Comparative application of direct sequencing, PCR-RFLP, and cytogenetic markers in the genetic characterization of Pimelodus (Siluriformes: Pimelodidae) species: Possible implications for fish conservation

Authors: M. Ferreira, K.C.O. Bressane, A.R.C. Moresco, O. Moreira-Filho, L.F. Almeida-Toledo and C. Garcia

Pimelodus (Pimelodidae) is a genus comprising a group of South American species with complex taxonomic relationships. Cytogenetics, polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP), and sequencing data of mitochondrial genes were analyzed to characterize 4 Pimelodus species: P. fur, P. heraldoi, P... Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.June.17.5
DOI:
http://dx.doi.org/10.4238/2014.June.17.5
Human Genetics   Research Article

Analysis of age of onset, pre-existing infections, and features of magnetic resonance imaging results in patients with acute myelitis

Authors: Q. Tang and H. Xiao

The clinical features and potential risk factors of acute myelitis (AM) were investigated. The medical records of patients with AM admitted to our department between January 2004 and December 2011 were collected and retrospectively analyzed. The diagnosis of AM was in line with the diagnostic criteria of the Transverse Myelitu.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.June.17.6
DOI:
http://dx.doi.org/10.4238/2014.June.17.6
Human Genetics   Research Article

Influence of interleukin-18 gene polymorphisms on acute pancreatitis susceptibility in a Chinese population

Authors: H.B. Gui, X.G. Du, Z.H. Fu and X.M. Chen

We investigate the relationship between IL-18 -607C/A and -137G/C genetic polymorphisms and development of acute pancreatitis in a Chinese population. A total of 153 patients were consecutively recruited from the First Affiliated Hospital of Chongqing Medical University between January 2013 and November 2014. Genotyping of IL-.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038394
DOI:
10.4238/gmr.15038394
Animal Genetics   Research Article

Growth hormone polymorphisms and growth traits in Chinese Tibetan sheep Ovis aries

Authors: Y.C. Han, Y.G. Sun and Q. Li

Growth hormone (GH) plays an important role in promoting growth, protein and muscle accretion, and fat catabolism, suggesting that GH is a potential candidate gene affecting growth traits in vertebrates. In this paper, polymorphisms in GH were investigated in 632 Chinese Tibetan sheep, by using DNA sequencing. Three single nucleotide polymorphisms were id.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038397
DOI:
10.4238/gmr.15038397
Medical Genetics   Research Article

Development of polymorphic microsatellite loci in Odontobutis obscura using Illumina paired-end sequencing and the test of cross-species amplification

Authors: H.-G. Bae, J. An, J. Jun, S.-M. Kweon, S. Kim, J.-N. Yu, B.-J. Kim, H. Sakai, Y.J. Lee and H.Y. Suk

Odontobutis obscura is a bottom-dwelling freshwater fish native to East Asia. Its range encompasses southwest China, western Japan, and Geoje Island in South Korea. Despite its widespread range in China and Japan, only a small and spatially isolated population is found in South Korea. We developed a total of 23 novel and polym.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038405
DOI:
10.4238/gmr.15038405
Medical Genetics   Research Article

Association between TNF-�± rs1800629 polymorphism and the risk of myocardial infarction: A meta-analysis

Authors: X.P. Hua, J. Qian, C.B. Cao, J. Xie, X.T. Zeng and Z.J. Zhang

The tumor necrosis factor-alpha (TNF-α) G-308A polymorphism has been suggested to be a susceptibility factor for myocardial infarction (MI). However, differing results from various studies have led to controversial conclusions. Hence, we performed a meta-analysis to evaluate the association between TNF-α G-308A pol.. Read More»

Genet. Mol. Res. 15(3):
gmr.15037292
DOI:
10.4238/gmr.15037292
Human Genetics   Research Article

Dynamical evaluation of vaginal micro-ecosystem in a Chinese woman with recurrent vulvovaginal candidiasis

Authors: Z.Q. Hu, W. Zhou, X.A. Yue, L.Y. Mu and Y.M. Jiang

We reported a rare case of recurrent vulvovaginal candidiasis (RVVC) in this study. Through dynamic evaluation of the vaginal micro-ecosystem, we found that only depuratory degree, spores, blastospores, and hyphae were specific indicators and the “barometer” of RVVC development. Therefore, an understanding of vaginal micro-ecological changes c.. Read More»

Genet. Mol. Res. 14(1):
http://dx.doi.org/2015.March.30.22
DOI:
http://dx.doi.org/10.4238/2015.March.30.22
Human Genetics   Research Article

Role of IL-6 polymorphism on the development of cardiovascular events and coronary artery disease in patients receiving hemodialysis

Authors: Y. Song, H.D. Gu, Y. He and J.W. Wang

We aimed to investigate the role of IL-6 polymorphism on the development of cardiovascular events and coronary artery disease in patients receiving hemodialysis. Blood samples were collected from 216 patients receiving hemodialysis treatment. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to genotype IL-6 -634C/G, -.. Read More»

Genet. Mol. Res. 14(1):
http://dx.doi.org/2015.March.30.23
DOI:
http://dx.doi.org/10.4238/2015.March.30.23
Animal Genetics   Research Article

Trans-translation ensures timely initiation of DNA replication and DnaA synthesis in Escherichia coli

Authors: W. Wurihan, W. Wunier, H. Li, L.F. Fan and M. Morigen

The trans-translation pathway, mediated by the transfer messenger RNA (tmRNA; encoded by the ssrA gene) and the SmpB protein (tmRNA-binding protein expressed in Salmonella enterica), which is conserved in bacteria, is required for various cellular processes. A previous study has shown that trans-translation is required to ensu.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038407
DOI:
10.4238/gmr.15038407