Epidemiological investigation of community-acquired Staphylococcus aureus infection
Authors: W. Jiang, Z. Zhou, K. Zhang and Y. Yu
The current study aimed to reveal the pathogenic and spreading mechanisms of community-acquired Staphylococcus aureus (CA-SA) by analyzing its prevalence, drug resistance, virulence, and pathogenic factors. Historical information regarding CA skin and soft tissue infections were collected and disease characteristics were analyzed. Isolated CA-SA strains w.. Read More»
- Genet. Mol. Res. 12(4):
- 2013
- DOI:
- 10.4238/2013
Luteinizing hormone receptor splicing variants in bovine Leydig cells
Authors: T.H. Ma, Q.H. Xiong, B. Yuan, H. Jiang, Y. Gao, J.B. Xu, S.Y. Liu, Y. Ding, G.L. Zhang, Y.M. Zhao and J.B. Zhang
The luteinizing hormone receptor (LHR) plays a key role in testosterone production through its interaction with the gonadotropins, LH and chorionic gonadotropin. We examined the LHR splicing pattern in bovine Leydig cells; LH-induced expression of eight cloned splicing variants was detected by real-time PCR. Luteinizing hormon.. Read More»
- Genet. Mol. Res. 11(2):
- http://dx.doi.org/2012.June.29.4
- DOI:
- http://dx.doi.org/10.4238/2012.June.29.4
Effect of a pre-microRNA-149 (miR-149) genetic variation on the risk of ischemic stroke in a Chinese Han population
Authors: Q.Y. Chen, N. Liu, J. Ma, Y. Fang, Y. Cao, H. Li and Y.C. Liu
Clinical and experimental data have demonstrated that genetic factors play an important role in determining the susceptibility to ischemic stroke (IS). The present study was performed to clarify the association between the pre-microRNA-149 (miR-149) single nucleotide polymorphism rs71428439 and the risk of IS in the Jiangsu Han population. Polymerase chai.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.17
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.17
Cyclin D1 G870A polymorphism is associated with an increased risk of multiple myeloma
Authors: S. Wang, Y. Huang, R. Su, Z. Fang and M. Han
Cyclin D1 is an important cell cycle regulator implicated in the pathogenesis of many cancer types. In particular, translocation and overexpression of cyclin D1 are common events in multiple myeloma (MM), suggesting that it may drive the initiation and progression of this malignancy. However, the association between genetic polymorphisms of cyclin D1 and .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.1.2
- DOI:
- 10.4238/2015.June.1.2
Patterns of synonymous codon usage bias in the model grass Brachypodium distachyon
Authors: H. Liu, Y. Huang, X. Du, Z. Chen, X. Zeng, Y. Chen and H. Zhang
Brachypodium distachyon has been proposed as a new model for the temperate grass because it is related to the major cereal grain species (such as wheat, barley, oat, maize, rice, and sorghum) and many forage and turf species. In this study, a multivariate statistical analysis was performed to investigate the characteristics of codon bias and the main factors.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.17.3
- DOI:
- 10.4238/2012.October.17.3
Inhibitory effect of alternatively spliced RAGEv1 on the expression of NF-kB and TNF-�± in hepatocellular carcinoma cells
Authors: T. Lertwittayapon, T. Tencomnao and R. Santiyanont
Binding of specific ligands to the receptor for advanced glycation end-products (RAGE) can trigger a series of signal transductions, which leads to pathogenesis in many chronic degenerative diseases, including cancer. Alternative splicing of RAGE mRNA has resulted in many variants, including RAGE variant 1 (RAGEv1). This parti.. Read More»
- Genet. Mol. Res. 11(2):
- http://dx.doi.org/2012.June.29.3
- DOI:
- http://dx.doi.org/10.4238/2012.June.29.3
Evaluation of the genetic diversity of Bupleurum using amplified fragment length polymorphism analysis
Authors: S.Y. Ke, L.L. Shi, Y.Z. Ma and X.J. Zhou
Radix bupleuri (Chaihu), the dried root of the Bupleurum plant, is an important component of traditional Chinese medicine. In this study, we examined the genetic diversity of 11 Bupleurum strains, originating from 7 provinces in China, using amplified fragment length polymorphism analysis. A total of 274 polymorphic bands were obtained using 6 primer comb.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.18
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.18
Meta-analysis demonstrates association between Arg72Pro polymorphism in the P53 gene and susceptibility to keloids in the Chinese population
Authors: Y. Wu, B. Wang, Y.H. Li, X.G. Xu, Y.J. Luo, J.Z.S. Chen, H.C. Wei, X.H. Gao and H.D. Chen
Although there is evidence suggesting genetic susceptibility for keloids, studies investigating the association between Arg72Pro polymorphism in the P53 gene and tendency to form keloids have given variable results. We made a meta-analysis of the effects of P53 Arg72Pro polymorphism on keloid risk in the Chinese population by .. Read More»
- Genet. Mol. Res. 11(2):
- http://dx.doi.org/2012.June.29.2
- DOI:
- http://dx.doi.org/10.4238/2012.June.29.2
Microsatellite analysis of genetic diversity and genetic structure in five consecutive breeding generations of mandarin fish Siniperca chuatsi (Basilewsky)
Authors: T.L. Yi, W.J. Guo, X.F. Liang, M. Yang, L.Y. Lv, C.X. Tian, Y. Song, C. Zhao and J. Sun
In this report, 10 polymorphic microsatellites were applied to assess the genetic diversity and genetic differentiation of 5 consecutive breeding generations of mandarin fish, Siniperca chuatsi (Basilewsky). The results from total number of alleles, average polymorphism information content, and average homozygosity and heterozygosity showed that the genet.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.19
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.19
Analysis of carcass and meat quality traits and nutritional values of hybrid wild boars under different crossing systems
Authors: S.-H. Zhang, L.-Y. Shen, J. Luo, Z.-H. Wu, Y.-Z. Jiang, G.-Q. Tang,M.-Z. Li, L. Bai, X.-W. Li and L. Zhu
The aim of this study was to analyze the results of two crossing systems between wild boars and different domesticated pig breeds. Hybrid wild boars were produced by crossing captured wild boars with Meishan pigs and LY sows according to the traditional production system. The resultant commercial hybrids were black and white in coat color, respectively. S.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.20
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.20