Y-STR haplotype diversity and population data for Central Brazil: implications for environmental forensics and paternity testing
Authors: T.C. Vieira, M.A.D. Gigonzac, D.M. Silva, R.G. Rodovalho, G.S. Santos and A.D. da Cruz
The central region of Brazil was colonized by internal migration of individuals of different origins, who contributed to the genetic diversity existing in this population. This study determined the allele frequencies and haplotype diversity of Y-STRs in Goiás State, Central Brazil, and compared the data obtained with a .. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.April.30.1
- DOI:
- http://dx.doi.org/10.4238/2014.April.30.1
Molecular characterization of cathepsin L cDNA and its expression during oogenesis and embryogenesis in the oriental river prawn Macrobrachium nipponense (Palaemonidae)
Authors: W. Zhao1,2, L. Chen1, F. Zhang1, P. Wu1, E. Li1 and J. Qin3
We identified the cDNA sequence of cathepsin L (CatL) in Macrobrachium nipponense, designated as MnCatL, for the first time. The MnCatL cDNA, isolated from the ovary, was 1710 bp in length, containing a 31-bp 5'-untranslated region, a 650-bp 3'-untranslated region, and an open reading frame of 1029 bp, encoding a 342-amino aci.. Read More»
- Genet. Mol. Res. 13(4):
- 2013.October.30.6
- DOI:
- 10.4238/2013.October.30.6
Molecular analysis of East Anatolian traditional plum and cherry accessions using SSR markers
Authors: M.H. ��z1, H. Vurgun1, M. Bakir2, �°. B�¼y�¼k3, C. Y�¼ksel2, H.M. ��nl�¼1, K. ��ukadar1, B. Karado��an1, ��. K�¶se3 and A. Erg�¼l2
We conducted SSR analyses of 59 accessions, including 29 traditional plum (Prunus domestica), 24 sweet cherry (Prunus avium), and 1 sour cherry (Prunus cerasus) selected from East Anatolian gene sources and 3 plum and 2 cherry reference accessions for molecular characterization and investigation of genetic relationships. Eight SSR loci [1 developed from t.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.7.6
- DOI:
- 10.4238/2013.November.7.6
Antigenotoxic and antimutagenic effects of Schinus terebinthifolius Raddi in Allium cepa and Swiss mice: A comparative study
Authors: L.E.S. Fedel-Miyasato, A.S.N. Formagio, S.A. Auharek, C.A.L. Kassuya, S.D. Navarro, A.L. Cunha-Laura, A.C.D. Monreal, M.C. Vieira and R.J. Oliveira
It is estimated that 60% of anticancer drugs are derived directly or indirectly from medicinal plants. Schinus terebinthifolius Raddi (Anacardiaceae) is traditionally used in Brazilian medicine to treat inflammation, ulcers, and tumors. Because of the need to identify new antimutagenic agents and to determine their mechanism o.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.April.30.2
- DOI:
- http://dx.doi.org/10.4238/2014.April.30.2
Effects of mycophenolate mofetil on the expression of monocyte chemoattractant protein-1 and fibronectin in high glucose cultured human mesangial cells
Authors: F.Q. Chen, Q.Y. Wang, G.Z. Wei, X.Y. Ma, D.W. Ma, W.W. Deng and W.B. Sun
The effects of high glucose on the expression of monocyte chemoattractant protein-1 (MCP-1) and the main component of the extracellular matrix, fibronectin (FN), were explored in human mesangial cells (HMCs), along with the intervention effects of mycophenolate mofetil (MMF) on these indicators. Cultured HMCs were divided into.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.17.11
- DOI:
- 10.4238/2014.April.17.11
Cloning, sequencing, and polymorphisms of the Wistar-Imamichi rat growth hormone gene using PCR-SSCP
Authors: M.Q. Liu1, J.G. Wang2* and X.L. Li2*
We successfully cloned the Wistar-Imamichi (WI) rat growth hormone gene (GenBank accession: GQ890681), which contained 5 exons and 4 introns. Using the polymerase chain reaction-single-strand conformation polymorphism (PCR-SSCP) technique, a novel missense substitution single nucleotide polymorphism was identified and tested for Hardy-Weinberg equilibrium.. Read More»
- Genet. Mol. Res. 13(4):
- 2013.December.4.7
- DOI:
- 10.4238/2013.December.4.7
Difference between ferritin genes overexpressing in transgenic tobacco
Authors: X. Tang, D. Zou, L. Zhang, C. Yang and T. Jiang
With the development of molecular biology techniques, intron was known as playing an imperative role in gene’s expression and regulation. Transgenic tobacco IN lines overexpressing InFer1 gene and NT lines overexpressing NtFer1 cDNA gene were obtained, and the exogenous gene expression were confirmed by molecular test. T.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.25.2
- DOI:
- 10.4238/2014.April.25.2
High genetic variation among Aschersonia placenta (Clavicipitaceae) isolates from citrus orchards in China
Authors: P.P. Wang1,2, X.H. Song1,3 and H.Y. Zhang
Aschersonia placenta had been recognized as an important fungal pathogen of whiteflies. In recent years, natural occurrence of Aschersonia in whitefly populations was observed in many citrus orchards in the southern regions of China. We analyzed 60 A. placenta isolates obtained from Chinese citrus orchards, using inter-simple sequence repeats to examine t.. Read More»
- Genet. Mol. Res. 13(4):
- 2013.December.4.6
- DOI:
- 10.4238/2013.December.4.6
Effect of variation of ABCB1 and GSTP1 on osteosarcoma survival after chemotherapy
Authors: J.Z. Li, Z.Q. Tian, S.N. Jiang and T. Feng
We conducted a comprehensive study to investigate the role of genes involved in metabolic and transport pathways in response to chemotherapy and clinical outcome of osteosarcoma patients. Genotyping of seven gene polymorphisms was performed on a 384-well plate format on the Sequenom MassARRAY platform in 162 patients with oste.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.25.3
- DOI:
- 10.4238/2014.April.25.3
Wilms' tumor suppressor gene mutations in girls with sporadic isolated steroid-resistant nephrotic syndrome
Authors: Y.H. Yang1*, F. Zhao1*, D.N. Feng1, J.J. Wang1, C.F. Wang1, J. Huang1, X.J. Nie1, G.Z. Xia1, G.M. Chen1 and Z.H. Yu1,2,3
Mutations in the Wilms' tumor suppressor gene (WT1) can lead to syndromic forms of steroid-resistant nephrotic syndrome (SRNS) such as Denys-Drash or Frasier syndrome and can cause isolated SRNS. A mutation within WT1 is a frequent cause of sporadic isolated SRNS in girls. In a worldwide cohort of girls, the rate of occurrence.. Read More»
- Genet. Mol. Res. 13(4):
- 2013.December.4.5
- DOI:
- 10.4238/2013.December.4.5