Effects of ginsenoside Rg1 on glucose metabolism and liver injury in streptozotocin-induced type 2 diabetic rats
Authors: W. Tian, L. Chen, L. Zhang, B. Wang, X.B. Li, K.R. Fan, C.H. Ai, X. Xia, S.D. Li, Y. Li
Type 2 diabetes mellitus (T2-DM) is a chronic metabolic disorder characterized by high blood glucose levels. T2-DM patients suffer from many complications, such as diabetic fatty liver and diabetic nephropathy. The liver, the pivotal organ involved in both glucose and lipid metabolism, is primarily damaged in T2-DM patients, e.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019463
- DOI:
- 10.4238/gmr16019463
Transforming growth factor beta-1 expression in macrophages of human chronic periapical diseases
Authors: Z.-Z. Liang, J. Li, S.-G. Huang
The objective of this study was to observe the distribution of macrophages (MPs) expressing transforming growth factor beta-1 (TGF-β1) in tissue samples from patients with different human chronic periapical diseases. In this study, samples were collected from 75 volunteers, who were divided into three groups according to .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019329
- DOI:
- 10.4238/gmr16019329
Associations between genetic variants and the severity of metabolic syndrome in subjects with type 2 diabetes
Authors: Y.L. Chen, D. Pei, Y.J. Hung, C.H. Lee, F.C. Hsiao, C.Z. Wu,J.D. Lin, C.H. Hsu, J.B. Chang and C.H. Hsieh
Metabolic syndrome (MetS) includes obesity, dyslipidemia, elevated blood pressure, and dysglycemia. Subjects with type 2 diabetes (T2D) exhibit features of MetS. The etiology of MetS is complex, involving both environmental and genetic factors. In this study, we examined the role of specific candidate genetic variants on the severity of MetS in T2D subjec.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.10
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.10
Evaluation of progenies from the fifth reciprocal recurrent selection cycle in maize
Authors: N.B. Alves, J.M.V. P�¡dua, K.O.G. Dias, R.P. Diniz, M.L. Guedes, G.A. Cardoso and J.C. Souza
The objective of this study was to evaluate the performance of 119 full sib progenies of the fifth cycle of reciprocal recurrent selection (RRS) derived from of Universidade Federal de Lavras maize breeding program. The experiment was carried out in an 11 x 11 triple lattice design at two locations (Lavras, Lambari). The plots consisted of two rows of 3 m.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.27.11
- DOI:
- 10.4238/2015.July.27.11
Analysis of SLC11A1 gene expression in healthy water buffalo (Bubalus bubalis) blood cells using qPCR
Authors: A. Cris� , G. De Matteis, M.C. Scat� and B. Moioli
SLC11A1 (solute carrier family 11 member 1 protein) gene influences the initial phase of bacterial cellular infections through macrophage activation. Recent literature on buffalo has attempted to associate the genotype of the polymorphic microsatellite located in the 3êÂ?Â?untranslated region (3êÂ?Â?UTR) of the gene, with either susceptibility to brucel.. Read More»
- Genet. Mol. Res. 12(4):
- 201
- DOI:
- 10.4238/201
Effect of overexpression of citrus 9-cis-epoxycarotenoid dioxygenase 3 (CsNCED3) on the physiological response to drought stress in transgenic tobacco
Authors: A.M. Pedrosa, L.C. Cidade, C.P.S. Martins, A.F. Macedo, D.M. Neves, F.P. Gomes, E.I.S. Floh, M.G.C. Costa
9-cis-epoxycarotenoid dioxygenase (NCED) encodes a key enzyme in abscisic acid (ABA) biosynthesis. Little is known regarding the regulation of stress response by NCEDs at physiological levels. In the present study, we generated transgenic tobacco overexpressing an NCED3 ortholog from citrus (CsNCED3) and investigated its relev.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019292
- DOI:
- 10.4238/gmr16019292
Influence of thoracic duct ligation on the lipid metabolism of patients with esophageal carcinoma after esophagectomy
Authors: J.P. Liu, Y.H. Zhang, B. Yang, Q. Chen and L. Cao
The aim of this study was to determine the influence of thoracic duct ligation on the lipid metabolism of patients with esophageal carcinoma after esophagectomy. A total of 74 patients with esophageal carcinoma who underwent esophagectomy were divided into 2 groups according to whether or not their thoracic duct was ligated. Thirty-nine patients were in t.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.11
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.11
Association of the genetic polymorphisms of NFKB1 with susceptibility to ovarian cancer
Authors: L.P. Chen, P.S. Cai and H.B. Liang
Nuclear factor-kB (NF-kB), a transcription factor that is activated by various stimuli, is associated with the pathogenesis of several cancers. One functional polymorphism, -94 insertion/deletion ATTG (rs28362491), in the human NFKB1 gene (one member of the NF-kB gene family) is associated with increased risk of various cancers. However, only one study ha.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.27.15
- DOI:
- 10.4238/2015.July.27.15
Disease indicators for sepsis and analysis of sepsis treatment in children using the continuous blood purification technique
Authors: J.P. Liu, X.W. Wang and L.P. Qie
We analyzed disease severity, inflammation markers, and dynamic changes in cartilage glycoprotein 39 (YKL-40) and Creactive protein (CRP) levels in children with sepsis before and after treatment with continuous blood purification (CBP). Study participants were 30 children with severe sepsis who were cured from the disease (experimental group) in the Chil.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.25.21
- DOI:
- 10.4238/2015.May.25.21
Comparative study of clinical efficacy of laparoscopy-assisted radical gastrectomy versus open radical gastrectomy for advanced gastric cancer
Authors: L.M. Wu, X.J. Jiang, Q.F. Lin and C.X. Jian
The purpose of this study is to compare the efficacy of laparoscopy-assisted radical gastrectomy (LARG) versus that of open radical gastrectomy (ORG). Clinical data of 355 patients who underwent radical gastrectomy (160 in the LARG group and 195 in the ORG group) were analyzed retrospectively. Efficacy indices were compared and analyzed between the two gr.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.15.9
- DOI:
- http://dx.doi.org/10.4238/2015.April.15.9