Simulation of normal, carrier and affected controls for large-scale genotyping of cattle for factor XI deficiency P.
Authors: P.N. Mukhopadhyaya, M. Jha, P. Muraleedharan, R.R. Gupta, R.N. Rathod, H.H. Mehta and V.K. Khoda
An insertion mutation within exon 12 of the factor XI gene has been described in Holstein cattle. This has opened the prospect for large-scale screening of cattle using the polymerase chain reaction (PCR) technique for the rapid identification of heterozygous animals. To facilitate such a screening process, the mutant and norm.. Read More»
- Genet. Mol. Res. 5(2):
Management of clinically negative nodes (N0) in supraglottic laryngeal carcinoma: A systematic review
Authors: Y.H. Liu and Z.W. Du
The purpose of this study was to evaluate the treatment of clinically negative cervical lymph nodes in supraglottic carcinoma by a meta-analysis. The search words were “supraglottic carcinoma”, “cervical lymph nodes negative/cN0”, “radical neck dissection”, and “radiotherapy”. Th.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15048179
- DOI:
- 10.4238/gmr15048179
Statistical analysis of the relationship between IL-10 gene promoter polymorphisms and the development of coronary artery disease
Authors: L. Wu, M.H. Zhao, G.Y. Geng, L. Mao and H.J. Liu
Here, we conducted a case-control study to investigate the association between IL-10 gene polymorphisms and development of CAD in a Chinese population. A total of 220 patients with CAD and 236 control subjects who visited the Zhengzhou People’s Hospital between May 2012 and June 2014 were selected for this study. The IL-.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15047823
- DOI:
- 10.4238/gmr15047823
Relationship of the methylenetetrahydrofolate reductase C677T polymorphism with microsatellite instability and promoter hypermethylation in sporadic colorectal cancer
Authors: Alessandra D. Clarizia, Luciana Bastos-Rodrigues, HeloÃ?Âsa B. Pena, Charles Anacleto, Benedito Rossi, Fernando A. Soares, Ademar Lopes, JosÃ?© ClÃ?¡udio C. Rocha, OtÃ?¡via Caballero, Anamaria Camargo, Andrew J.G. Simpson and SÃ?©rgio D.J. Pena
The methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism is associated with the expression of a thermolabile enzyme with decreased activity that influences the pool of methyl-donor molecules. Several studies have reported an association between C677T polymorphism and susceptibility to colorectal cancer (CRC). Conside.. Read More»
- Genet. Mol. Res. 5(2):
Amino acid composition of royal jelly harvested at different times after larval transfer
Authors: H. Jie, P.M. Li, G.J. Zhao, X.L. Feng, D.J. Zeng, C.L. Zhang, M.Y. Lei, M. Yu and Q. Chen
The amino acids in royal jelly (RJ) have a wide range of pharmacological and health-promoting functions in humans. Multiple studies on the amino acid quality and composition in RJ have investigated RJ harvested at 72 h after larval transfer. In contrast, the concentration of amino acids in RJ harvested before 72 h remains unknown. In this study, the conce.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038306
- DOI:
- 10.4238/gmr.15038306
Rehmannia glutinosa oligosaccharide induces differentiation of bone marrow mesenchymal stem cells into cardiomyocyte-like cells
Authors: X.H. Wang, H.W. Du, X.H. Guo, S.W. Wang, R.B. Zhou, Y. Li, Z.B. Li, Y.S. Zhao and Q.L. Zhu
The aim of this study was to observe the effect of Rehmannia glutinosa oligosaccharide (RGO) on differentiation of bone marrow mesenchymal stem cells (MSCs) into cardiomyocyte-like cells . Rat MSCs were isolated, treated, and grouped as follows: RGO treatment group, 5-azacytidine (5-aza) treatment group, RGO + 5-aza treatment .. Read More»
- Genet. Mol. Res. 15(4):
- gmr15047795
- DOI:
- 10.4238/gmr15047795
Sampling strategies for natural Toona ciliata populations
Authors: J. Liu and J.M. Jiang
The genetic diversity and spatial autocorrelation of Toona ciliata populations were analyzed with eight microsatellite markers to determine an appropriate sampling strategy for the effective conservation of natural T. ciliata populations. The average number of alleles and effective number of alleles were 6.1 and 2.7, respectiv.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15047751
- DOI:
- 10.4238/gmr15047751
Biological, serological and molecular typing of potato virus Y (PVY) isolates from Tunisia
Authors: M. Tayahi, C. Gharsallah, N. Khamassy, H. Fakhfakh and F. Djilani-Khouadja
In Tunisia, potato virus Y (PVY) currently presents a significant threat to potato production, reducing tuber yield and quality. Three hundred and eighty-five potato samples (six different cultivars) collected in autumn 2007 from nine regions in Tunisia were tested for PVY infection by DAS-ELISA. The virus was detected in all .. Read More»
- Genet. Mol. Res. 15(4):
- gmr15045165
- DOI:
- 10.4238/gmr15045165
Morphological evolution and heritability estimates for some biometric traits in the Murgese horse breed
Authors: C. Dario, D. Carnicella, M. Dario and G. Bufano
A data set concerning 1,816 subjects entered in the Italian Horse Registry from 1925 to 2002 was analyzed to investigate the morphological evolution of the Murgese horse and to obtain useful elements to enhance breeding practices. Three basic body measurements (height at withers, chest girth, and cannon bone circumference) wer.. Read More»
- Genet. Mol. Res. 5(2):
Genetic potential of black bean genotypes with predictable behaviors in multienvironment trials
Authors: P.P. Torga, P.G.S. Melo, H.S. Pereira, L.C. Faria and L.C. Melo
The aim of this study was to evaluate the phenotypic stability and specific and broad adaptability of common black bean genotypes for the Central and Center-South regions of Brazil by using the Annicchiarico and AMMI (weighted average of absolute scores: WAAS, and weighted average of absolute scores and productivity: WAASP) me.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049029
- DOI:
- 10.4238/gmr15049029