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Plant Genetics   Research Article

Correlations and path analysis among agronomic and technological traits of upland cotton

Authors: F.J.C. Farias, L.P. Carvalho, J.L. Silva Filho and P.E. Teodoro

To date, path analysis has been used with the aim of breeding different cultures. However, for cotton, there have been few studies using this analysis, and all of these have used fiber productivity as the primary dependent variable. Therefore, the aim of the present study was to identify agronomic and technological properties that can be used as criteria .. Read More»

Genet. Mol. Res. 15(3):
gmr.15038239
DOI:
10.4238/gmr.15038239
Human Genetics   Research Article

A combination of five short tandem repeats of chromosome 15 significantly improves the identification of Prader-Willi syndrome etiology in the Argentinean population

Authors: H.V. Ar�¡oz, M. Torrado, C. Barreiro and L. Chertkoff

Prader-Willi syndrome (PWS) is a multisystemic disorder caused by the loss of expression of paternally transcribed genes in the PWS critical region of chromosome 15. Various molecular mechanisms are known to lead to PWS: deletion 15q11-q13 (75% of cases), maternal uniparental disomy (matUPD15) (23%) and imprinting defects (2%).. Read More»

Genet. Mol. Res. 5(2):
Medical Genetics   Research Article

Discovery of clubroot-resistant genes in Brassica napus by transcriptome sequencing

Authors: S.W. Chen T. Liu, Y. Gao, C. Zhang, S.D. Peng, M.B. Bai, S.J. Li, L. Xu, X.Y. Zhou and L.B. Lin

Clubroot significantly affects plants of the Brassicaceae family and is one of the main diseases causing serious losses in B. napus yield. Few studies have investigated the clubroot-resistance mechanism in B. napus. Identification of clubroot-resistant genes may be used in clubroot-resistant breeding, as well as to elucidate the molecular mechanism behind.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038243
DOI:
10.4238/gmr.15038243
Human Genetics   Research Article

Serum microRNA-135a downregulation as a prognostic marker of non-small cell lung cancer

Authors: Y.K. Zhang, B. Sun and G. Sui

Abnormal expression of microRNA-135a (miR-135a) is closely associated with oncogenesis. However, the relationship between serum miR-135a levels and the clinical parameters and prognosis of non-small cell lung cancer (NSCLC) remain unclear. The study aimed to investigate the clinical significance of serum miR-135a expression in patients with NSCLC. miR-135.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038252
DOI:
10.4238/gmr.15038252
Plant Genetics   Research Article

Incongruent evolution of chromosomal size in rice

Authors: X. Guo, G. Xu, Y. Zhang, X. Wen, W. Hu and L. Fan

To investigate genome size evolution, it is usually informative to compare closely related species that vary dramatically in genome size. A whole genome duplication (polyploidy) that occurred in rice (Oryza sativa) about 70 million years ago has been well documented based on current genome sequencing. The presence of three dis.. Read More»

Genet. Mol. Res. 5(2):
Plant Genetics   Research Article

Population structure analysis and association mapping of blast resistance in indica rice (Oryza sativa L.) landraces

Authors: Y.Y. Wu, J.B. He, A.H. Li, N.Y. Fang, W.W. He, L.L. Dang, G.Y. Zeng, J. Huang, Y.M. Bao and H.S. Zhang

Rice blast caused by Magnaporthe oryzae is one of the most devastating rice diseases worldwide. To understand the genetic diversity of indica landrace accessions and identify simple sequence repeat (SSR) markers that are associated with blast resistance, a population of 276 indica landraces from across the world was constructed. This population was then u.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038254
DOI:
10.4238/gmr.15038254
Medical Genetics   Review Article

Study of the influence of ethanol on basic fibroblast growth factor structure

Authors: G.H. Brancaleoni, M.R. Lourenzoni and L. Degr�¨ve

The growth of cells is controlled by stimulatory or inhibitory factors. More than twenty different families of polypeptide growth factors have been structurally and functionally characterized. Basic fibroblast growth factor (bFGF) of the fibroblast growth factor family was characterized in 1974 as having proliferative activity.. Read More»

Genet. Mol. Res. 5(2):
Animal Genetics   Research Article

A cytogenetics study of Hydrodroma despiciens (M�¼ller, 1776) (Acari: Hydrachnellae: Hydrodromidae)

Authors: Serap Tutgun Onrat, Ferruh Ax�§i and Muhlis ��zkan

The karyotypes of water mites (Acari: Hydrachnellae: Hydrodromidae) are largely unknown. The present investigation is the first report of a study designed to characterize the chromosomes of water mites. The study was carried out with specimens of Hydrodroma despiciens collected from Eber Lake in Afyon, Turkey. Several differen.. Read More»

Genet. Mol. Res. 5(2):
Human Genetics   Research Article

Expression and tyrosine phosphorylation of sp32 regulate the activation of the boar proacrosin/acrosin system

Authors: H.T. Dong, W.S. Shi, Y. Tian, L.P. Cao and Y. Jin

The current study investigated the relationship between the level of expression and tyrosine phosphorylation of the sperm protein 32 (sp32) and the activation of the boar proacrosin/acrosin system. The acrosomal membrane proteins of boar sperm for use in different treatment experiments (i.e., fresh sperm, freezing and thawing, capacitation, and acrosome r.. Read More»

Genet. Mol. Res. 14(1):
2015.March.27.23
DOI:
10.4238/2015.March.27.23
Bioinformatics   Review Article

PDB-Metrics: a Web tool for exploring the PDB contents

Authors: Renato Fileto, Paula R. Kuser, Michel E.B. Yamagishi, Andr�© A. Ribeiro, Thiago G. Quinalia, Eduardo H. Franco, Adauto L. Mancini, Roberto H. Higa, Stanley R.M. Oliveira, Edgard H. Santos, Fabio D. Vieira, Ivan Mazoni, Sergio A.B. Cruz and Goran Neshich

PDB-Metrics (http://sms.cbi.cnptia.embrapa.br/SMS/ pdb_metrics/index.html) is a component of the Diamond STING suite of programs for the analysis of protein sequence, structure and function. It summarizes the characteristics of the collection of protein structure descriptions deposited in the Protein Data Bank (PDB) and provid.. Read More»

Genet. Mol. Res. 5(2):