Propofol suppresses proliferation and invasion of gastric cancer cells via downregulation of microRNA-221 expression

Authors: Z.T. Wang, H.Y. Gong, F. Zheng, D.J. Liu and X.Q. Yue

Propofol is one of the extensively and commonly used intravenous anesthetic agents. The current study aimed to evaluate the effects of propofol on the behavior of human gastric cancer cells and the molecular mechanisms of this activity. The effects of propofol on SGC7901 and AGS cell proliferation, apoptosis, and invasionwere detected by MTT assay, flow c.. Read More»

Genet. Mol. Res. 14(3):

2015.July.17.20

DOI:

10.4238/2015.July.17.20

Use of sugarcane molasses by Pycnoporus sanguineus for the production of laccase for dye decolorization

Authors: R.A. Marim, A.C.C. Oliveira, R.S. Marquezoni, J.P.R. Servantes,B.K. Cardoso, G.A. Linde, N.B. Colauto and J.S. Valle

Pycnoporus sanguineus is a white-rot basidiomycete that produces laccase as the only oxidoreductase; enzyme synthesis depends on cultivation variables, and fungal species and strain. Laccases have wide substrate specificity, oxidize a broad range of compounds, and show potential for use in dye decolorization. We evaluated lacc.. Read More»

Genet. Mol. Res. 15(4):

gmr15048972

DOI:

10.4238/gmr15048972

Dry matter content in cassava and interspecific hybridization

Authors: N.M.A. Nassar

Genet. Mol. Res. 9(2):

vol9-2gmr772

DOI:

10.4238/vol9-2gmr772

Novel genetic male sterility developed in (Capsicum annuum x C. chinense) x C. pubescens and induced by HNO2 showin Mendelian inheritance and aborted at telophase of microspore mother cell stage

Authors: W. Huang, J.-J. Ji, C. Li, G.-Q. Li, C.-C. Yin, W.-G. Chai and Z.-H. Gong

A novel genetic male sterile germplasm was developed by successively crossing of (C. annuum x C. chinense) x C. pubescens and by chemical mutagenesis in pepper. The sterile anthers showed morphological abnormalities, but pistils developed normally with fine pollination capability. We investigated fertility segregation through sib-crossing of the same stra.. Read More»

Genet. Mol. Res. 14(2):

http://dx.doi.org/2015.April.13.11

DOI:

http://dx.doi.org/10.4238/2015.April.13.11

Chromosome 7 translocation breakpoints in male carriers: clinical features and implications for genetic counseling

Authors: R.X. Wang, H.G. Zhang, Y. Pan, J.H. Zhu, F.G. Yue, L.T. Xue and R.Z. Liu

Balanced reciprocal translocations are associated with reproductive failure. Some reciprocal translocation carriers exhibit azoospermia or oligozoospermia, and an association exists between these chromosomal abnormalities and recurrent abortion. Previous reports have indicated the involvement of chromosome 7 translocations in .. Read More»

Genet. Mol. Res. 15(4):

gmr15048948

DOI:

10.4238/gmr15048948

Association of ATP1A1 gene polymorphism with heat tolerance traits in dairy cattle

Authors: Y.X. Liu, X. Zhou, D.Q. Li, Q.W. Cui and G.L. Wang

Heat stress produces oxidative stress and affects the alternation of plasma K+ and Na+. Since Na+,K+-ATPase is sensitive to oxidative stress and critical for maintaining the homeostasis of these two ions, we examined the genetic polymorphism of the ATP1A1 gene in 160 Holstein cows using polymerase chain reaction low ionic stre.. Read More»

Genet. Mol. Res. 9(2):

vol9-2gmr769

DOI:

10.4238/vol9-2gmr769

Determination of the genetic relationships between wild olive (Olea europaea oleaster) varieties grown in the Aegean region

Authors: M. Sesli and E.D. YeÃ?Â?enoÃ?Â?lu

The RAPD technique was used for determining genetic differences between 12 wild-olive varieties grown in the Aegean provinces of Izmir, Mugla, and Manisa in Turkey. Wild olives obtained from the same provinces were included in the same plot. Twenty of 25 operon primers (OP-I 4, OP-I 14, OP-I 15, OP-I 16, OP-I 17, OP-Q1, OP-Q2,.. Read More»

Genet. Mol. Res. 9(2):

vol9-2gmr792

DOI:

10.4238/vol9-2gmr792

Polymorphisms in the IGF1 gene and their effect on growth traits in Mexican beef cattle

Authors: X.F. De la Rosa Reyna, H.M. Montoya, V.V. Castrell�³n, A.M.S. Rinc�³n, M.P. Bracamonte and W.A. Vera

The IGF1 gene (insulin-like growth factor 1) is a candidate gene for marker-assisted selection strategies. A single nucleotide polymorphism in the promoter region (IGF1/SnaBI) has been reported to be associated with production traits in several cattle breeds. Here, we report its allelic frequencies in Charolais and Beefmaster .. Read More»

Genet. Mol. Res. 9(2):

vol9-2gmr745

DOI:

10.4238/vol9-2gmr745

Polymorphic CA microsatellites in the third exon of the bovine BMP4 gene

Authors: X. Zhong, L.S. Zan, H.B. Wang and Y.F. Liu

We examined the variation of the BMP4 gene in four Chinese indigenous cattle breeds and investigated the association of this polymorphism with body measurement traits. Using PCR-SSCP and DNA sequencing, a polymorphic microsatellite was detected in the third exon of the bovine BMP4 gene in 459 samples from four Chinese indigeno.. Read More»

Genet. Mol. Res. 9(2):

vol9-2gmr732

DOI:

10.4238/vol9-2gmr732

Cloning and quantitative expression analysis of drought-induced genes in soybean

Authors: R. Stolf-Moreira, M.E. Medri, N. Neumaier, N.G. Lemos, R.L. Brogin, F.C. Marcelino, M.C.N. de Oliveira, J.R.B. Farias, R.V. Abdelnoor and A.L. Nepomuceno

We determined the expression levels of DREB transcription factor (Gmdreb1) and of the genes Gmgols, Gmpip1b, Gmereb, and Gmdefensin in drought-tolerant (MG/BR46-Conquista) and drought-sensitive (BR16) genotypes of soybean, during drought. The trial was carried out in a controlled-environment chamber, set up to provide drought .. Read More»

Genet. Mol. Res. 9(2):

vol9-2gmr701

DOI:

10.4238/vol9-2gmr701