All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Human Genetics   Research Article

Lack of association of ACE gene I/D polymorphism with obstructive sleep apnea syndrome in Turkish patients

Authors: T. Yakut, M. Karkucak, A. Ursavas, T. Gulten, B. Burgazlioglu, O. Gorukmez and M. Karadag

Angiotensin-converting enzyme (ACE) is a vital enzyme in the renin-angiotensin-aldosterone system, and there are reports in the literature describing its role in the development of cardiovascular system diseases, with I/D polymorphism of the ACE gene. We examined the relationship between a patient group with obstructive sleep .. Read More»

Genet. Mol. Res. 9(2):
vol9-2gmr755
DOI:
10.4238/vol9-2gmr755
Plant Genetics   Research Article

Cloning and expression analysis of terpenoid metabolism-related gene NsyCMS in Nicotiana sylvestris

Authors: J. Lv, G.S. Liu, W. Li, Z. Hussian and Y.H. Sun

Terpenoids constitute the main class of secondary metabolites produced in plants with industrial, pharmacological, and agricultural interests. Nicotiana sylvestris has been widely adopted as a diploid model system in plant biology for studies of terpenoid biosynthesis. In this paper, we report the isolation and analysis of the 2-C-methyl-d-erythritol 2,4-.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.13.9
DOI:
http://dx.doi.org/10.4238/2015.April.13.9
Plant Genetics   Research Article

Selection of common bean genotypes for the Cerrado/Pantanal ecotone via mixed models and multivariate analysis

Authors: A.M. Corr�ªa, M.I.S. Moraes, H.K.A. de Abreu, T. Sharon, C.L.P. de Melo, M.A. Ito, P.E. Teodoro and L.L. Bhering

The common bean, Phaseolus vulgaris, is predominantly grown on small farms and lacks accurate genotype recommendations for specific micro-regions in Brazil. This contributes to a low national average yield. The aim of this study was to use the methods of the harmonic mean of the relative performance of genetic values (HMRPGV) .. Read More»

Genet. Mol. Res. 15(4):
gmr15048888
DOI:
10.4238/gmr15048888
Animal Genetics   Research Article

Influence of Chinese breeds on pork quality of commercial pig lines

Authors: A.S.M. Cesar, A.C.P. Silveira, P.F.A. Freitas, E.C. Guimar�£es, D.F.A. Batista, L.C. Torido, F.V. Meirelles and R.C. Antunes

We compared carcass and meat quality of pigs from the same sire line and two different dam lines, one that included Chinese breeds and one that did not. Line A consisted of 1/4 Landrace, 1/2 Large White, 1/8 Chinese breeds (Meishan, Fengjing, Jiaxing), and 1/8 Large White, Duroc and Pietrain, and line B consisted of 1/2 Large .. Read More»

Genet. Mol. Res. 9(2):
vol9-2gmr733
DOI:
10.4238/vol9-2gmr733
Human Genetics   Research Article

Expression and significance of SATB1 in the development of breast cancer

Authors: S. Zhang, X. Gao, Y. Ma, J. Jiang, Z. Dai, X. Yin, W. Min, W. Hui and B. Wang

Special AT-rich sequence binding protein 1 (SATB1) is a recently discovered gene regulator that can promote the growth and metastasis of breast cancer. However, its expression in different stages of breast cancer development have not been examined. We explored the role of SATB1 in the development of breast cancer by detecting SATB1 expression levels in di.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.13.10
DOI:
http://dx.doi.org/10.4238/2015.April.13.10
Human Genetics   Research Article

Mechanisms of antioxidant defense in the state of post-hypoxia in Phrynops geoffroanus (Testudines: Chelidae)

Authors: N.R.A. Costa, L.P.R. Venancio,and C.R. Bonini-Domingos

hrynops geoffroanus (Testudines: Chelidae), comprises a group of reptiles that are tolerant to variations in environmental oxygen availability. Due to this characteristic, they are considered an excellent model for studies that aim the understanding of the physiological and biochemical mechanisms involved in the resistance to .. Read More»

Genet. Mol. Res. 15(4):
gmr15049308
DOI:
10.4238/gmr15049308
Human Genetics   Research Article

DNA repair genes in endometriosis

Authors: R. Attar, C. Cacina, S. Sozen, E. Attar and B. Agachan

Several polymorphisms in the DNA repair gene are thought to have significant effects on cancer risk. We investigated the association of polymorphisms in the DNA repair genes XRCC1 Arg399Gln, XRCC3 Thr241Met, XPD Lys751Gln, XPG Asp1104His, APE1 Asp148Glu, and HOGG1 Ser326Cys with endometriosis risk. Genotypes were determined by.. Read More»

Genet. Mol. Res. 9(2):
vol9-2gmr779
DOI:
10.4238/vol9-2gmr779
Human Genetics   Research Article

Expression of acid phosphatase in the seminiferous epithelium of vertebrates

Authors: R.L. Peruquetti, S.R. Taboga and M.T.V. Azeredo-Oliveira

Acid phosphatases (AcPs) are known to provide phosphate to tissues that have high energy requirements, especially during development, growth and maturation. During spermatogenesis AcP activity is manifested in heterophagous lysosomes of Sertoli cells. This phagocytic function appears to be hormone-independent. We examined the .. Read More»

Genet. Mol. Res. 9(2):
vol9-2gmr730
DOI:
10.4238/vol9-2gmr730
Human Genetics   Research Article

Karyotype evolution in the genus Jacaranda Juss. (Jacarandeae, Bignoniaceae): chromosome numbers and heterochromatin

Authors: J.M.P. Cordeiro, S.A.A. Lima, S.N. Paz, A.M.S. Santos and L.P. Felix

Most taxa in the Bignoniaceae have 2n = 40, but the basal clade Jacarandeae has 2n = 36, suggesting that x = 18 is the ancestral basic number for the family. Variations in heterochromatin band patterns in genera that are numerically stable, such as Jacaranda, could facilitate our understanding of the chromosomal and karyotypic.. Read More»

Genet. Mol. Res. 15(4):
gmr15048973
DOI:
10.4238/gmr15048973
Human Genetics   Research Article

Mediterranean fever gene mutation analysis in infertile Turkish males

Authors: E.O. Etem, D. Erol , Y. Huseyin and A. Arslan

Male infertility is a common barrier that prevents successful conception. There have been reports of azoospermia in men with familial Mediterranean fever, some of whom had not been treated with colchicine. Variation in this disorder could be a risk factor for amyloidosis associated with azoospermia. We determined the frequency.. Read More»

Genet. Mol. Res. 9(2):
vol9-2gmr743
DOI:
10.4238/vol9-2gmr743