Editor Note on Cardiovascular Genetics
Authors: M. Akram
Numerous cardiovascular issues can be acquired, including arrhythmias, innate coronary illness, cardiomyopathy, and high blood cholesterol. Coronary corridor sickness prompting respiratory failure, stroke, and cardiovascular breakdown can run in families, demonstrating acquired hereditary danger factors. Hereditary qualities can impact the danger for coro.. Read More»
- Genet. Mol. Res. 20(1):
Analysis of Micro-RNAs and Gene Expression Profiles in Gestational Diabetes Mellitus: A Consensus Approach
Authors: R. Bhushan, A. Rani, D. Gupta, I. Khan, A. Tripati, R. P. Singh and K. D. Pawan
Gestational Diabetes Mellitus (GDM) is a metabolic disorder characterized by insulin resistance. Lack of complete mechanisms involved in its pathophysiology makes its early diagnosis and treatment a difficult task. Recently, micro-RNAs are associated with many diseases including GDM. Its high stability in biological fluids and the ability to modulate gene.. Read More»
- Genet. Mol. Res. 20(1):
Diagnosis of Idiopathic Primary Infertility in a Consanguineous Infertile Family using Clinical and Molecular Cytogenetic Techniques
Authors: H. Muhammad, R. Khan, F. Wahab, I. Khan, B. Shah, A. Ali, N. Farooqi, Dil, N. Ali, F. Jalil and S. Ali
Background: Male infertility is a multifactorial medical problem affecting around 7% of the male population in whom 1% are affected by Non Obstructive Azoospermia (NOA). Despite of advanced diagnostic techniques, majority of the infertility cases remain idiopathic .Therefore more evidence based scientific research is required to investigate the underlying.. Read More»
- Genet. Mol. Res. 19(5):
Endothelial Nitric Oxide Synthase (eNOS) Gene Polymorphisms and Risk of Aneurysmal Subarachnoid Hemorrhage: An Updated Meta-Analysis
Authors: N. Manabesh, M. Shubham, K. Amit, S. Rakhee, K. Pradeep
Previously published studies have examined whether the polymorphisms (G894T, 4b/a, and T786C) in the Endothelial Nitric Oxide Synthase (eNOS) gene are associated with risk of Aneurysmal Subarachnoid Hemorrhage (aSAH), have reported conflicting results. Thus, we performed a meta-analysis to examine the potential association between these three single nucle.. Read More»
- Genet. Mol. Res. 19(5):
Environment Association in Chickpea Genotypes Utilizing AMMI And GGE Biplot Model
Authors: M.G. Azam, M.S. Iqba, M.A. Hossain and M.F. Hossain
Chickpea (Cicer arietinum L.) is generally grown-up underneath rainfed conditions inside the Barind space in Bangladesh, any place drought spell is that the principle production constraint. Genotype × Environment Interaction (GEI) was acclimated with making estimation of the grain yield and to get a handle on the G × E connection designs by an.. Read More»
- Genet. Mol. Res. 19(4):
Fourier-Transform Infrared Spectroscopy, Antioxidant, Phytochemical and Antibacterial Screening of N-Hexane Extracts of Punica granatum, A Medicinal Plant
Authors: M. Sharif, F. Ansari, A. Malik, Q. Ali, Z. Hasan and N.U.H. Khan
Pomegranate is a fruit bearing plant belonging to Lythraceae; in botanic language it is called Punica granatum. It is been considered as a traditional medicine for the cure of many diseases. The purpose of this study was to investigate the antimicrobial activity and phytochemicals present qualitatively present in different parts of Pomegranate plant and t.. Read More»
- Genet. Mol. Res. 19(4):
Development and Transferability of Microsatellites Markers for Species of the Saltans Group of Drosophila (Diptera: Drosophilidae)
Authors: B.E. Roman, B.M. Trava and L. Madi-Ravazzi
The microsatellite markers (SSRs) are highly polymorphic, fast evolving, and regarded as neutral markers. Due to these traits, they have been widely used in population studies. The development of specific SSRs for a given species opens possibilities for the application, by means of transferability, in population studies of other species that are phylogene.. Read More»
- Genet. Mol. Res. 19(4):
Molecular Characterization of Tuf Gene and Antibiotic Susceptibility Patterns of Streptococcus Species in Local Population of Lahore, Pakistan
Authors: A. Mahmood, A. J. Sami and Q. Ali
Background: Multi Drug Resistance (MDR) is a global problem which is expeditiously increasing. Different antimicrobial drugs have been reported resistant against various Streptococcus species. This has been a threat to local individuals in all over the world specifically in developing countries including Pakistan. Decreased efficiency of drugs due to emer.. Read More»
- Genet. Mol. Res. 19(4):
Targeted Delivery of Insulin by Psyllium Plant (Plantago ispaghula) based hydrogels/membranes
Authors: A.J. Sami, U. Ahmad, M. Karamat, M.N. Hafeez and Q. Ali
Developments in therapeutics are the need of hour for the benefit of mankind and to increase the quality of life. Diabetes mellitus is a non-curable disease affecting a great amount of world’s population. This genetic disorder gets worse with time and ultimately leads to various complications like renal failure, lower limb amputation, heart diseases.. Read More»
- Genet. Mol. Res. 19(2):
Knock down of molt regulating gene for development control of Helicoverpa armigera
Authors: M.N. Sharif, M.S. Iqbal, R. Alam, B. Tabassum, M.F. Awan, Q. Ali and I.A. Nasir
RNA interference (RNAi) caused by exogenous double-stranded RNA (dsRNA) is a powerful tool, and to date is widely adopted to knockdown genetic targets crucial for growth and development of agriculturally important insect pests. Helicoverpa armigera is a pest feeding on more than 30 economically important crops worldwide and a major threat. Resistance to i.. Read More»
- Genet. Mol. Res. 19(2):