Codon usage bias analysis for the spermidine synthase gene from Camellia sinensis (L.) O. Kuntze
Authors: E. You, Y. Wang, Z.T. Ding, X.F. Zhang, L.L. Pan and C. Zheng
The spermidine synthase (SPDS) gene exists widely in all types of plants. In this paper, the codon usage of the SPDS gene from Camellia sinensis (CsSPDS) was analyzed. The results showed that the codon usage of the CsSPDS gene is biased towards the T-ended or A-ended codons, which is similar to that observed in 73 genes selected from the C. sinensis genom.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.3.12
- DOI:
- 10.4238/2015.July.3.12
Investigation of the value of miR-21 in the diagnosis of early stage HCC and its prognosis: a meta-analysis
Authors: S.R. Yan, Z.J. Liu, S. Yu and Y.X. Bao
The diagnostic and prognostic value of miR-21 has been examined for hepatocellular carcinoma (HCC), with inconsistent results. Present meta-analysis summarized the diagnostic accuracy and the predictive role for survival of miR-21 in patients with HCC. All eligible studies were searched using PubMed, EMBASE, and Chinese National Knowledge Infrastructure (.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.28.9
- DOI:
- http://dx.doi.org/10.4238/2015.September.28.9
Elimination of breast tumor-associated chondroitin sulfate promotes metastasis
Authors: R.D. Prinz, C.M. Willis, A. Viloria-Petit and M. Kl�¼ppel
Breast cancer is one of the leading causes of cancer-related deaths amongst women in the USA. The tumor microenvironment has been suggested to be an attractive therapeutic target for treatment of cancers. The glycosaminoglycan chondroitin sulfate, as part of the cellular microenvironment, consists of long linear chains of repe.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.8.9
- DOI:
- 10.4238/2011.December.8.9
Genetic relationships among and within wild and cultivated olives based on RAPDs
Authors: M. Sesli and E.D. YeÃ?Â?enoÃ?Â?lu
We examined genetic relationships among wild and cultivated olives, which is a very important crop in the economy of the Aegean region. We used RAPD analysis to evaluate relationships among and within 22 olive subspecies from Manisa, Mugla and Izmir provinces in Turkey. Twelve of the subspecies were wild and 10 were cultivated.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr866
- DOI:
- 10.4238/vol9-3gmr866
Correlation between the BRAF V600E mutation status and the clinicopathologic features of papillary thyroid carcinoma
Authors: C.L. Shi, Y. Sun, C. Ding, Y.C. Lv and H.D. Qin
This study sought to investigate the correlations of V-raf murine sarcoma viral oncogene homolog B1 (BRAF) gene mutations with the clinicopathologic features of papillary thyroid carcinoma and central lymph node metastasis. We retrospectively analyzed the 2-year medical records of patients who underwent surgery for papillary thyroid carcinoma. After scree.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.3.13
- DOI:
- 10.4238/2015.July.3.13
Genomic structure, polymorphism and expression analysis of growth hormone-releasing hormone and pituitary adenylate cyclase activating polypeptide genes in the half-smooth tongue sole (Cynoglossus semilaevis)
Authors: Q. Ma, S.F. Liu, Z.M. Zhuang, L. Lin, Z.Z. Sun, C.L. Liu, Y.Q. Su and Q.S. Tang
Growth hormone-releasing hormone (GHRH) and pituitary adenylate cyclase activating polypeptide (PACAP) regulate development and somatic growth in teleosts; they may be associated with sexual growth dimorphism in the half-smooth tongue sole (Cynoglossus semilaevis). We found that the full-length GHRH and PACAP gene sequences ob.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.12.1
- DOI:
- 10.4238/2011.December.12.1
Different responses to doxorubicin-induced chromosome aberrations in Brazilian deer species
Authors: D.S.F. Vargas-Munar, J.A. Sarria-Perea and J.M.B. Duarte
The tendency toward chromosome fragility is one of the theories that may explain chromosome variation in brocket deer species (genus Mazama). We tested doxorubicin as an inducer of chromosome aberrations in lymphocytes of three brocket deer species, Mazama gouazoubira, M. americana and M. nana, compared to the marsh deer, Blas.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr822
- DOI:
- 10.4238/vol9-3gmr822
Genetic variability of genes involved in DNA repair influence treatment outcome in osteosarcoma
Authors: M.J. Wang, Y. Zhu, X.J. Guo and Z.Z. Tian
We conducted a perspective study to investigate the role of ERCC1 (rs11615), ERCC2 (rs13181 and rs1799793), ERCC4 (rs1800067), and ERCC5 (rs17655) in NER pathway in the prognosis of osteosarcoma patients. In total, 146 osteosarcoma patients were recruited between 2008 and 2013. ERCC1 rs11615, ERCC2 rs13181 and rs1799793, ERCC4 rs1800067, and ERCC5 rs17655.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.28.17
- DOI:
- http://dx.doi.org/10.4238/2015.September.28.17
AFLP markers for identification of Swertia species (Gentianaceae)
Authors: A. Misra, A.K. Shasany, A.K. Shukla, M.P. Darokar, S.C. Singh, V. Sundaresan, J. Singh, G.D. Bagchi, S.P. Jain1, D. Saikia and S.P.S. Khanuja
The genus Swertia is well known for its medicinal properties, as described in the Indian pharmacopoeia. Different members of this genus, although somewhat similar in morphology, differ widely in their pharmacological and therapeutic properties. The most important species of this genus, with maximal therapeutic properties, is S.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr785
- DOI:
- 10.4238/vol9-3gmr785
rbcS SRS4 promoter from Glycine max and its expression activity in transgenic tobacco.
Authors: X.Y. Cui, Z.Y. Chen, L. Wu, X.Q. Liu, Y.Y. Dong, F.W. Wang and H.Y. Li
The regulatory region of the ribulose-1,5-bisphosphate carboxylase small subunit gene SRS4 from soybean (Glycine max) was cloned using TAIL-PCR and general PCR, and named the rbcS promoter. The promoter was fused with the GUS gene and introduced into Nicotiana tabacum via Agrobacterium-mediated leaf disk transformation. In 4-week-old transgenic tobacco pl.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.3.15
- DOI:
- 10.4238/2015.July.3.15