Tetraploidization in Wilms tumor in an infant
Authors: E.T. Valera*, M.S. Brassesco*, C.A. Scrideli and L.G. Tone
Genetic instability is frequent in human cancer. Unscheduled tetraploidization can trigger cell transformation and tumorigenesis. We made a cytogenetic analysis by Giemsa-trypsin banding of a stage I, biphasic Wilms tumor diagnosed in a 10-month-old male. An evident karyotypic heterogeneity was found. Four different subclones .. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr880
- DOI:
- 10.4238/vol9-3gmr880
Phenotypic correlations between ovum pick-up in vitro production traits and pregnancy rates in Zebu cows
Authors: W.H.O. Vega, C.R. Quirino, R.V. Serapi�£o, C.S. Oliveira and A. Pacheco
The growth of the Gyr breed in Brazil in terms of genetic gain for milk, along with conditions for market, has led to the use of ovum pick-up in vitro production (OPU-IVP) as a leader in biotechnology for the multiplication of genetic material. The aim of this study was to investigate phenotypic correlations between OPU-IVP-linked characteristics and preg.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.3.9
- DOI:
- 10.4238/2015.July.3.9
Molecular characterization of Calocedrus rupestris Aver., H.T. Nguyen & L.K. Phan, 2008 (Cupressaceae) based on ITS1 partial sequence
Authors: P.K. Long, N.T.P. Trang, L.V. Averyanov and P.K. Loc
Calocedrus rupestris Aver., H.T. Nguyen & L.K. Phan was described in 2008 based on some morphological characters that were not sufficiently significant to discriminate it as a species distinct from C. macrolepis Kurz. We applied a new approach to resolve these conflicting views by using sequence data from DNA (ITS) to eluc.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.November.21.1
- DOI:
- 10.4238/2011.November.21.1
Genetic diversity of eggplant (Solanum melongena) germplasm from Turkey assessed by SSR and RAPD markers
Authors: K. Demir, M. Bak�±r, G. Sar�±kam�±�� and S. Acunalp
Eggplant is a major crop in Turkey, which produces more of this crop than all of Europe; consequently, germplasm resources are of concern for the country. Molecular characterization of eggplant genotypes collected from different geographical regions of Turkey was carried out using SSR and RAPD markers. With amplification of fi.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr878
- DOI:
- 10.4238/vol9-3gmr878
Resistance to lipopolysaccharide-induced endotoxic shock in heterozygous Zfp191 gene-knockout mice
Authors: R.L. Sun, H.Y. Wang, X.Y. Yang, Z.J. Sheng, L.M. Li, L. Wang, Z.G. Wang and J. Fei
Zinc finger protein 191, ZNF24 and Zfp191 in both humans and mice belong to the SCAN domain subfamily of Krüppel-like zinc finger transcription factors. Previous studies have suggested that Zfp191 is a pleiotropic factor involved in embryonic development, hematopoiesis and tumorigenesis. However, little is known about its.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.8.6
- DOI:
- 10.4238/2011.December.8.6
Correlation between single nucleotide polymorphisms in hypoxia-related genes and susceptibility to acute high-altitude pulmonary edema
Authors: A.L. Wu, Y.S. Xiong, Z.Q. Li, Y.G. Liu, Q. Quan and L.J. Wu
This study aimed to explore the relationship between genetic changes and high-altitude pulmonary edema (HAPE) susceptibility, and to screen for the key single nucleotide polymorphism (SNP) loci in the HAPE-susceptibility gene, by investigating the SNPs occurring in hypoxia-related genes in HAPE-susceptible and control (non-susceptible) populations. This r.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.28.8
- DOI:
- http://dx.doi.org/10.4238/2015.September.28.8
Functional molecular markers (EST-SSR) in the full-sib reciprocal recurrent selection program of maize (Zea mays L.)
Authors: K.S.C. Galv�£o, H.C.C. Ramos, P.H.A.D. Santos, G.C. Entringer, J.C.F. Vettorazzi and M.G. Pereira
This study aimed to improve grain yield in the full-sib reciprocal recurrent selection program of maize from the North Fluminense State University. In the current phase of the program, the goal is to maintain, or even increase, the genetic variability within and among populations, in order to increase heterosis of the 13th cycle of reciprocal recurrent se.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.3.10
- DOI:
- 10.4238/2015.July.3.10
RNA interference-mediated URG4 gene silencing diminishes cyclin D1 mRNA expression in HepG2 cells
Authors: N.L. Satiroglu-Tufan, Y. Dodurga, D. Gok, A. Cetinkaya and M.A. Feitelson
Up-regulated gene 4 (URG4), stimulated by HBxAg, is a novel gene located on chromosome 7 (7p13). The full-length URG4 clone is 3.607 kb and encodes a polypeptide of 922 amino acids, with a molecular weight of 104 kDa (GeneID: 55665). It promotes cell growth, growth factor-independent survival, and anchorage-independent growth .. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr872
- DOI:
- 10.4238/vol9-3gmr872
Genetic linkage map of Cucurbita maxima with molecular and morphological markers
Authors: Y. Ge, X. Li, X.X. Yang, C.S. Cui and S.P. Qu
Cucurbita maxima is one of the most widely cultivated vegetables in China and exhibits distinct morphological characteristics. In this study, genetic linkage analysis with 57 simple-sequence repeats, 21 amplified fragment length polymorphisms, 3 random-amplified polymorphic DNA, and one morphological marker revealed 20 genetic linkage groups of C. maxima .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.22.18
- DOI:
- 10.4238/2015.May.22.18
Comparison of bacterial communities in the Solim�µes and Negro River tributaries of the Amazon River based on small subunit rRNA gene sequences
Authors: J.C.C. Peixoto, L. Leomil, J.V. Souza, F.B.S. Peixoto and S. Astolfi-Filho
The microbiota of the Amazon River basin has been little studied. We compared the structure of bacterial communities of the Solimões and Negro Rivers, the main Amazon River tributaries, based on analysis of 16S rRNA gene sequences. Water was sampled with a 3-L Van Dorn collection bottle; samples were collected at nine d.. Read More»
- Genet. Mol. Res. 10(4):