Analysis of genetic diversity and population structure in a tomato (Solanum lycopersicum L.) germplasm collection based on single nucleotide polymorphism markers
Authors: T. Wang, Q.D. Zou, S.Y. Qi, X.F. Wang, Y.Y. Wu, N. Liu, Y.M. Zhang, Z.J. Zhang and H.T. Li
Knowledge of genetic diversity is important to assist breeders in the selection of parental materials and in the design of breeding programs. In this study, we genotyped 348 inbred tomato lines, representing vintage and contemporary fresh-market varieties, by using 52 single nucleotide polymorphisms (SNPs); 45 of these were found to be polymorphic. The av.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038209
- DOI:
- 10.4238/gmr.15038209
CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis
Authors: X. Wang and Y. He
Cytochrome P4502E1 (CYP2E1) is a key enzyme in the metabolic activation of many carcinogens, but the roles of CYP2E1 polymorphisms in cervical neoplasia (CN) are inconclusive. Published case-control cohort studies from the Pubmed, Embase, and China National Knowledge Infrastructure databases were retrieved. Data were extracted and pooled odds ratios with .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.18.11
- DOI:
- 10.4238/2015.May.18.11
Isolation and characterization of the papaya MADS-box E-class genes, CpMADS1 and CpMADS3, and a TM6 lineage gene CpMADS2
Authors: M.-J. Lee, W.-J. Yang, C.-T. Chiu, J.-J. Chen, F.-C. Chen and L.-S. Chang
Papaya (Carica papaya L.) plants are polygamous, with female, male, and hermaphroditic flowers. To understand the roles of MADS-box genes in flower development and sex determination, we cloned cDNAs of E-class genes CpMADS1 and CpMADS3 and a TM6 lineage of the B-class gene CpMADS2 from young.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.24.9
- DOI:
- 10.4238/2014.July.24.9
Genome-wide comparison of AP2/ERF superfamily genes between Gossypium arboreum and G. raimondii
Authors: Z.P. Lei, D.H. He, H.Y. Xing, B.S. Tang and B.X. Lu
The APETALA2/ethylene response factor (AP2/ERF) transcription factor superfamily is known to regulate diverse processes of plant development and stress responses. We conducted a genome-wide analysis of the AP2/ERF gene in Gossypium arboreum and G. raimondii. Using RPSBLAST and HMMsearch, a total of 271 and 269 AP2/ERF genes were identified in the G. arbor.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038211
- DOI:
- 10.4238/gmr.15038211
Association of the TNF-�± +489 G/A polymorphism with chronic obstructive pulmonary disease risk in Asians: meta-analysis
Authors: K. Cui, X.Y. Ge and H.L. Ma
The association between the TNF-α +489 G/A polymorphism and chronic obstructive pulmonary disease (COPD) remains controversial because of small group size and varied design among different studies. In the present study, a meta-analysis was conducted to assess the association between the +489 G/A polymorphism and COPD risk. A comprehensive search was.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.18.12
- DOI:
- 10.4238/2015.May.18.12
Relationship between RFC gene expression and intracellular drug concentration in methotrexate-resistant osteosarcoma cells
Authors: J.J. Wang and G.J. Li
Osteosarcoma is a primary malignant tumor in adolescents, associated with high mortality and morbidity. The high-dose methotrexate (MTX) chemotherapy used to treat this disease may induce primary or secondary drug resistance, resulting in a reduced effect of comprehensive treatment. In this study, the relationship between redu.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.24.10
- DOI:
- 10.4238/2014.July.24.10
Photosynthesis enhanced oxidative stress tolerance in high-yield rice varieties (Oryza sativa var. japonica L.) in the field
Authors: X.D. Wei, L. Jin and X. Li
The objective of this study was to understand varietal differences in photosynthetic characteristics, chlorophyll fluorescence, antioxidant capability, and yield of japonica rice varieties. Nanjing 44, Oryza sativa var. japonica (average yield of 12.7 t/ha), Nanjing 46, and Nanjing 5055 (average yields of 11.3 and 11.5 t/ha) were included as “super&.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038247
- DOI:
- 10.4238/gmr.15038247
Flaxseed oil supplementation alters the expression of inflammatory-related genes in dogs
Authors: D. Purushothaman, W.Y. Brown, B.A. Vanselow, K. Quinn and S.-B. Wu
Long chain n-3 fatty acids are beneficial to mammals because of their anti-inflammatory role. However, whether flaxseed oil, which is rich in short chain n-3 fatty acids, has such a role, it has not been extensively examined. This study investigated the supplementation of flaxseed oil on the regulation of gen.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.24.11
- DOI:
- 10.4238/2014.July.24.11
Polymorphism of UGT1A1*28 (TA)7 and liver damage in hepatitis B virus-positive patients in Albania
Authors: E. Marku, P.E. Maltese, M. Koni, N. Capodicasa, I.S. Qendro, E. Rigoni, S. Cecchin and M. Bertelli
Hepatitis B virus (HBV) is the infectious agent of both acute and chronic hepatitis. HBV exists in multiple genotypic variants that differ in their capacity to become persistent chronic infections and in their clinical manifestations, including hepatocellular carcinoma. The 8 genotypes (A-H) of HBV show a specific worldwide geographic distribution and are.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.18.13
- DOI:
- 10.4238/2015.May.18.13
Evidence of balancing selection in multiple indigenous chicken populations
Authors: S. Arlud, G.X. E and S.C. Zeng
Microsatellite DNA markers, which are assumed to drift, have been widely used to assess genetic diversity in all major domestic animal species. These markers provide insight into the arrival and dispersion history of a species, with regard to their content or management history. However, no direct evidence supports current standard microsatellite markers .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038249
- DOI:
- 10.4238/gmr.15038249