Paracoccidioides brasiliensis RNA biogenesis apparatus revealed by functional genome analysis
Authors: Patr�?cia Albuquerque, Alessandra J. Baptista, Lorena da Silveira Derengowsky, Luciano Proc�?³pio, Andr�?© Moraes Nicola, Fabr�?cio B.M. Arraes, Diorge Paulo de Souza, Cynthia Maria Kyaw and Ildinete Silva-Pereira
The RNA biogenesis machinery of Paracoccidioides brasiliensis was assessed by comparative analyses of PbAESTs (P. brasiliensis assembled expressed sequence tags (ESTs)) with sequences from Saccharomyces cerevisiae MIPS database. PbAESTs related to almost all categories of S. cerevisiae RNA biogenesis were found. Two of the 12 .. Read More»
- Genet. Mol. Res. 4(2):
General metabolism of the dimorphic and pathogenic fungus Paracoccidioides brasiliensis
Authors: Fabr�?cio B.M. Arraes, Bruno Benoliel, Rafael T. Burtet, Patr�?cia L.N. Costa, Alexandro S. Galdino, Luanne H.A. Lima, Camila Marinho-Silva, Luciana Oliveira-Pereira, Pollyanna Pfrimer, Luciano Proc�?³pio-Silva, Viviane Castelo-Branco Reis and Maria Sueli S. Felipe
Annotation of the transcriptome of the dimorphic fungus Paracoccidioides brasiliensis has set the grounds for a global understanding of its metabolism in both mycelium and yeast forms. This fungus is able to use the main carbohydrate sources, including starch, and it can store reduced carbons in the form of glycogen and trehal.. Read More»
- Genet. Mol. Res. 4(2):
Paracoccidioides brasiliensis translation and protein fate machineries revealed by functional genome analysis
Authors: Diorge Paulo de Souza, Simoneide Souza Silva, Alessandra J. Baptista, Andr�?© Moraes Nicola, Cynthia M. Kyaw and Ildinete Silva-Pereira
The translational and post-translational modification machineries of Paracoccidioides brasiliensis were assessed by means of comparative analyses of PbAESTs (P. brasiliensis assembled expressed sequence tags) with sequences deposited on different databases. Of the 79 sequences corresponding to cytosolic ribosomal proteins, we .. Read More»
- Genet. Mol. Res. 4(2):
Cell cycle, DNA replication, repair, and recombination in the dimorphic human pathogenic fungus Paracoccidioides brasiliensis
Authors: Viviane Castelo Branco Reis, Fernando Araripe Gon�?§alves Torres, Marcio Jos�?© Po�?§as-Fonseca, Marlene Teixeira De-Souza, Diorge Paulo de Souza, Jo�?£o Ricardo Moreira Almeida, Camila Marinho-Silva, N�?¡dia Skorupa Parachin, Alessandra da Silva Dantas, Thiago Machado Mello-de-Sousa and L�?dia Maria Pepe de Moraes
DNA replication, together with repair mechanisms and cell cycle control, are the most important cellular processes necessary to maintain correct transfer of genetic information to the progeny. These processes are well conserved throughout the Eukarya, and the genes that are involved provide essential information for understand.. Read More»
- Genet. Mol. Res. 4(2):
Cell signaling pathways in Paracoccidioides brasiliensis - inferred from comparisons with other fungi
Authors: Larissa Fernandes, Marcus A.M. Ara�?ºjo, Andr�?© Amaral, Viviane Castelo Branco Reis, Nat�?¡lia F. Martins and M.S. Felipe
The human fungal pathogen Paracoccidioides brasiliensis is an ascomycete that displays a temperature-dependent dimorphic transition, appearing as a mycelium at 22°C and as a yeast at 37°C, this latter being the virulent form. We report on the in silico search made of the P. brasiliensis transcriptome-expressed sequence.. Read More»
- Genet. Mol. Res. 4(2):
Molecular cloning, characterization, and expression analysis of a Broad-Complex homolog during development in the oriental river prawn Macrobrachium nipponense
Authors: S.F. Jiang, Y.P. Zhang, S.M. Sun, Y.S. Gong, Y.W. Xiong, H. Qiao, W.Y. Zhang, S.B. Jin and H.T. Fu
Broad-Complex (BR-C) is an early ecdysone-responsive gene encoding a family of zinc-finger transcription factors. In this study, we isolated the full-length cDNA of a BR-C homolog from the testes of the oriental river prawn (Macrobrachium nipponense), according to established expressed sequence tag information, using the rapid amplification of cDNA ends t.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.18.4
- DOI:
- 10.4238/2015.May.18.4
Bioinformatics of the Paracoccidioides brasiliensis EST Project
Authors: Marcelo M. Br�?gido, Maria Em�?lia M.T. Walter, Adilton G. Oliveira, Marcus K. Inoue, Daniel S. Anjos, Edans F.O. Sandes, Jo�?£o J. Gondim, Maria Jos�?© de A. Carvalho, Nalvo F. Almeida Jr. and Maria Sueli Soares Felipe
Paracoccidioides brasiliensis is the etiological agent of paracoccidioidomycosis, an endemic mycosis of Latin America. This fungus presents a dimorphic character; it grows as a mycelium at room temperature, but it is isolated as yeast from infected individuals. It is believed that the transition from mycelium to yeast is impor.. Read More»
- Genet. Mol. Res. 4(2):
Genetic structure and diversity in natural and stocked populations of the mandarin fish (Siniperca chuatsi) in China
Authors: M. Yang, C. Tian, X.-F. Liang, H. Zheng, C. Zhao and K. Zhu
The Chinese perch, or mandarin fish (Siniperca chuatsi), is a freshwater fish that is endemic to East Asia. In this study, we investigated the genetic diversity and structure of nine natural mandarin fish populations (from the Yangtze River and Amur River basins) and six hatchery stocks (from central and south China) using microsatellite markers. The resu.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.18.5
- DOI:
- 10.4238/2015.May.18.5
Genetic variation and population structure of two species of neo-tropical mud-mussels (Mytella spp)
Authors: Miguel E.G.C. de Oliveira, Claudia A.M. Russo, Cristiano Lazoski, Paulo Roberto F.G. Vianna and Antonio M. Sol�?©-Cava
Mytella guyanensis Lamarck (1819) and Mytella charruana d’Orbigny (1846) are widespread euryhaline bivalves that have become commercially important in Brazil. Despite their importance, however, no genetic information that would be useful to orient governmental policies is available for these species. We analyzed, through.. Read More»
- Genet. Mol. Res. 4(2):
Effects and mechanism of cerebroprotein hydrolysate on learning and memory ability in mice
Authors: L. An, X. Han, H. Li, Y. Ma, L. Shi, G. Xu, G. Yuan, J. Sun, N. Zhao, Y. Sheng, M. Wang and P. Du
Cerebroprotein hydrolysate is an extract from porcine brain tissue that acts on the central nervous system in various ways to protect neurons and improve memory, attention, and vigilance. This study examined the effect and mechanism of cerebroprotein hydrolysate on learning and memory in mice with scopolamine-induced impairment. Mice were given an intrape.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038804
- DOI:
- 10.4238/gmr.15038804