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Plant Genetics   Research Article

Complete mitochondrial genome sequence of Cheirotonus jansoni (Coleoptera: Scarabaeidae)

Authors: L.L. Shao, D.Y. Huang, X.Y. Sun, J.S. Hao, C.H. Cheng, W. Zhang and Q. Yang

We sequenced the complete mitochondrial genome (mitogenome) of Cheirotonus jansoni (Coleoptera: Scarabaeidae), an endangered insect species from Southeast Asia. This long legged scarab is widely collected and reared for sale, although it is rare and protected in the wild. The circular genome is 17,249 bp long and contains a ty.. Read More»

Genet. Mol. Res. 13(1):
2014.February.20.6
DOI:
10.4238/2014.February.20.6
Animal Genetics   Research Article

Comparative analysis of mucosal immunity to Mycoplasma hyopneumoniae in Jiangquhai porcine lean strain and DLY piglets

Authors: L.Z. Hua, Y.Z. Wu, F.F. Bai, K.K. William, Z.X. Feng, M.J. Liu, J.T. Yao, X. Zhang and G.Q. Shao

The Jiangquhai porcine lean strain (JQHPL) is a new pork meat-type strain that has been developed in recent years from the parent lines Duroc, Fengjing, and Jiangquhai pigs (DurocxFengjing pigxJiangquhai pig). Enzootic pneumonia (EP) in pigs induced by Mycoplasma hyopneumoniae (M. hyopneumoniae) is a chronic .. Read More»

Genet. Mol. Res. 13(3):
2014.July.7.13
DOI:
10.4238/2014.July.7.13
Plant Genetics   Research Article

Effect of the extract from leaves of Liquidambar formosana Hance on S180 cells

Authors: Y.T. Zhong, X.L. Wang, Q.J. Xie and Y.N. Zhang

We examined the effects of the extract from leaves of Liquidambar formosana Hance on S180 cells and screened for antitumor active sites in the plant. Solvent extraction was conducted to prepare extracts from the leaves of L. formosana Hance and conduct preliminary separation, an MTT assay to determine the effect of leaf extract on the proliferation of S18.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038795
DOI:
10.4238/gmr.15038795
Animal Genetics   Research Article

Influence of environmental static electric field on antioxidant enzymes activities in hepatocytes of mice

Authors: S.X. Wu, Y.Q. Xu, G.Q. Di, J.H. Jiang, L. Xin and T.Y. Wu

With the increasing voltage of direct current transmission line, the intensity of the environmental static electric field has also increased. Thus, whether static electric fields cause biological injury is an important question. In this study, the effects of chronic exposure to environmental static electric fields on some antioxidant enzymes activities in.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038800
DOI:
10.4238/gmr.15038800
Human Genetics   Research Article

KCNQ1 A340E impairs electrolyte homeostasis independently of the renin-angiotensin-aldosterone system in mice

Authors: Q. Pan, Y. Sang, C. Sun, G. Li and Y. Wang

KCNQ1 (KvLQT1) is the pore-forming a-subunit of the potassium channel. To uncover its role in electrolyte metabolism, we investigated the effects of KCNQ1 A340E, a loss-of-function mutant, on J343 mice. Compared with the normal controls (C57BL/6J mice) bearing the wild-type KCNQ1 gene, J343 mice bearing KCNQ1 A340E demonstrated a much higher 24-h intake o.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038802
DOI:
10.4238/gmr.15038802
Plant Genetics   Research Article

Mutagenic potential of Cordia ecalyculata alone and in association with Spirulina maxima for their evaluation as candidate anti-obesity drugs

Authors: R.P. Araldi, B.M. Rechiutti, T.B. Mendes, E.T. Ito and E.B. Souza

Obesity is one of the most important nutritional disorders, and can be currently considered as an epidemic. Although there are few weight reduction drugs available on the market, some new drug candidates have been proposed, including Cordia ecalyculata, a Brazilian plant with anorectic properties, and Spirulina ma.. Read More»

Genet. Mol. Res. 13(3):
2014.July.7.14
DOI:
10.4238/2014.July.7.14
Medical Genetics   Research Article

IFGFA: Identification of featured genes from genomic data using factor analysis

Authors: C.H. Fu, S. Deng, J.H. Wu, X.Q. Wu, Z.H. Fu and Z.G. Yu

In this study, a software tool (IFGFA) for identification of featured genes from gene expression data based on latent factor analysis was developed. Despite the availability of computational methods and statistical models appropriate for analyzing special genomic data, IFGFA provides a platform for predicting colon cancer-related genes and can be applied .. Read More»

Genet. Mol. Res. 15(3):
gmr.15038803
DOI:
10.4238/gmr.15038803
Medical Genetics   Research Article

Effects of the Zhikang capsule on healing of the flap after radical breast cancer surgery

Authors: C. Cheng, Y. Lv, E. Zhang, T. Yan, C. Li, D.-X. Hou and J.-H. Li

This study aimed to investigate the effect and mechanism of trauma flap healing promoted by the Zhikang capsule after radical breast cancer surgery. The enrolled breast cancer patients were randomly divided into two groups: treatment and observation. The patients in the treatment group were treated with the Zhikang capsule in addition to the conventional .. Read More»

Genet. Mol. Res. 14(2):
2015.May.18.2
DOI:
10.4238/2015.May.18.2
Plant Genetics   Research Article

Genetically modified crops: Brazilian law and overview

Authors: C.D. Marinho, F.J.O. Martins, A.T. Amaral J�ºnior, L.S.A. Gon�§alves, O.J.A.P. dos Santos, D.P. Alves, B.P. Brasileiro and L.A. Peternelli

In Brazil, the first genetically modified (GM) crop was released in 1998, and it is estimated that 84, 78, and 50% of crop areas containing soybean, corn, and cotton, respectively, were transgenic in 2012. This intense and rapid adoption rate confirms that the choice to use technology has been the main factor in developing nat.. Read More»

Genet. Mol. Res. 13(3):
2014.July.7.15
DOI:
10.4238/2014.July.7.15
Human Genetics   Research Article

Effect of ultraviolet A exposure on transport of compatible organic osmolytes in human lens epithelial cells

Authors: D.Y. Wu and J.S. Zhang

Compatible organic osmolytes, such as betaine, myoinositol, and taurine, are involved in antioxidant defense, protein stabilization, and stress responses. This osmolyte strategy requires the expression of specific osmolyte transporters such as betaine (BGT-1), myoinositol (SMIT), and taurine (TAUT). In contrast to the kidney, keratinocytes, and neural cel.. Read More»

Genet. Mol. Res. 14(2):
2015.May.18.3
DOI:
10.4238/2015.May.18.3