
Authors: J.C.M. Dornelas, J.E.F. Figueiredo, C.S. de Abreu, U.G.P. Lana, C.A. Oliveira and I.E. Marriel
Secondary metabolites produced by Actinobacteria of tropical soils represent a largely understudied source of novel molecules with relevant application in medicine, pharmaceutical and food industries, agriculture, and environmental bioremediation. The present study aimed to characterize sixty-nine Actinobacteria isolated from .. Read More»
Authors: M.F. Lima, S.I.C. Carvalho, C.F. Ragassi, L.B. Bianchetti, F.G. Faleiro and F.J.B. Reifschneider
Germplasm banks are essential as sources of genetic variability for plant breeding programs. To characterize a Brazilian Capsicum frutescens collection, 21 malagueta and 5 Tabasco hot pepper accessions were evaluated under field and greenhouse conditions regarding morphological and molecular traits, as well as resistance to vi.. Read More»
Authors: F.C.F. Vieira, A.M. Gon�§alves, E.F.R. Mendoza, R.M. Ferreira, M.L.M. Costa, T.S. Balbuena, H.G. Sebinelli, P. Ciancaglini, J.M. Pizauro Junior and J.A. Ferro
Citrus canker, caused by the Gram-negative bacterium Xanthomonas citri subsp citri (Xac), severely affects most economically important citrus varieties worldwide. A previous study showed that disruption of the ORF XAC1201 from the Xac 306 strain by transposon Tn5 decreased bacterium virulence in the Rangpur lime host (Citrus l.. Read More»
Authors: M.S. Regueira Neto, R.P. Barros, M.A.J. Morais, V.Q. Balbino and V. Loreto
In Brazil, the species Diatraea flavipennella and D. saccharalis play an important role in the sugar and alcohol agribusiness by causing many damages in sugarcane fields. The egg, larva, pupa, and adult stages are very morphologically similar between these species, and the identification can be confused. The internal transcribed spacer 2 (ITS 2) from ribo.. Read More»
Authors: I.R. Carvalho, A.J. de Pelegrin, V.J. Szareski, M. Ferrari, T.C. da Rosa, T.S. Martins, N.L. dos Santos, M. Nardino, V.Q. de Souza, A.C. de Oliveira and L.C. da Maia
Genetic improvement is essential to achieve increments in maize (Zea mays L.) grain yield components. It may be obtained through crosses, which enable to exploit the effects of intervarietal heterosis, allelic complementarity, as well as gene actions and effects. This study estimated the components of variance and genetic para.. Read More»
Authors: N. Carvalho, F.M. Canela, P.H.S. Leite, M.A. Ferreira, V.R. Oliveira, M.F. Santos, N.O.S. Souza and G.S.C. Buso
Taking into account the scenario of melon production (Cucumis melo L.) in Brazil, it is notable the importance of the culture in the fruit market. The preference of the national market is concentrated in the fruits of the yellow type. Therefore, it is possible that the genetic base of the commercial cultivars is relatively nar.. Read More»
Authors: G.A. Molfetta, D.L. Zanette, J.E. Santos and W.A. Silva Jr
Familial hypercholesterolemia (FH) is a dominant, autosomal disease characterized by high LDL levels in blood plasma, and is caused by a defect in the gene encoding the LDL receptor (LDLR). The clinical diagnosis is based on personal and familial history, physical examination findings, and measures of high LDL cholesterol conc.. Read More»
Authors: B.W. Zago, M.A.A. Barelli, E.S.S. Hoogerheide, C.L. CorrĂ?ÂȘa,G.I.S. Delforno and C.J. da Silva
Genetic variability of cassava (Manihot esculenta Crantz) in Brazil is wide, being this the result of natural and cultural selection during pre- and post-domestication of the species in different environments. Given the number of species of the genus found in the region (38 of a total of 98 species), the central region of Braz.. Read More»
Authors: H.N. Heim, E.S.N. Vieira, L.R.T. Polo, N.K. Lima, G.J. Silva, G.A. Linde, N.B. Colauto and I. Schuster
One of the limiting factors in using dominant markers is the unique amplification of the target fragment. Therefore, failures in polymerase chain reaction (PCR) or non-amplifications can be interpreted as an absence of the allele. The possibility of false negatives implies in reduced efficiency in the selection process in gene.. Read More»
Authors: T. Zhang, J.G. Wan, J.B. Liu and M. Deng
The forkhead box F2 (Foxf2) gene suppresses epithelial-mesenchymal transition via the modulation of transcription of zinc finger E-box-binding homeobox 1 (Zeb1) and epithelial (E)-cadherin, thereby inhibiting tumor metastasis. Additionally, the specific binding of microRNA (miR)-200c to Foxf2 mRNA impedes metastatic pulmonary .. Read More»