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Microbial Genetics   Research Article

A RAPD-PCR-based genetic diversity analysis of Helicoverpa armigera and H. zea populations in Brazil

Authors: H.M. Lopes, C.S. Bastos, L.S. Boiteux, J. Foresti and F.A. Suinaga

Helicoverpa armigera is the most significant pest of agriculture in Asia, Europe, Africa, and Australasia, causing damage to crops greater than US$2 billion annually and until 2013 it was not detected in Brazil. Helicoverpa zea is restricted to the American continent and is important to corn and a secondary pest of cotton and .. Read More»

Genet. Mol. Res. 16(3):
gmr16038757
DOI:
10.4238/gmr16038757
Human Genetics   Research Article

Clinical features of Mexican patients with Mucopolysaccharidosis type I

Authors: A. Alonzo-Rojo, J.E. Garc�­a-Ortiz, M. Ortiz-Aranda, M.P. Gallegos-Arreola and L.E. Figuera-Villanueva

Mucopolysaccharidosis type I (MPS-I) is an autosomal recessive lysosomal storage disorder caused by a deficiency or absence of α-l-iduronidase, which is involved in the catabolism of glycosaminoglycans (GAGs). This deficiency leads to the accumulation of GAGs in several organs. Given the wide spectrum of the disease, MPS.. Read More»

Genet. Mol. Res. 16(3):
gmr16032602
DOI:
10.4238/gmr16032602
Bioinformatics   Research Article

Characterization of glucose-tolerant �²-glucosidases used in biofuel production under the bioinformatics perspective: a systematic review

Authors: D.C.B. Mariano, C. Leite, L.H.S. Santos, L.F. Marins, K.S. Machado, A.V. Werhli, L.H.F. Lima and R.C. de Melo-Minardi

β-glucosidases are enzymes that catalyze the hydrolysis of oligosaccharides and disaccharides, such as cellobiose. These enzymes play a key role in cellulose degrading, such as alleviating product inhibition of cellulases. Consequently, they have been considered essential for the biofuel industry. However, the majority of.. Read More»

Genet. Mol. Res. 16(3):
gmr16039740
DOI:
10.4238/gmr16039740
Human Genetics   Research Article

Role of IL17A rs2275913 and rs3748067 polymorphisms in the risk cervical cancer

Authors: A.Q. Niu, Y.H. Cao, H. Wang, X. Zhang, B. Zhu and Z.H. Li

Cervical cancer is a serious public health problem and is associated with high cancer-related mortality in females worldwide. The expression of IL17A can increase the migration and invasiveness of cervical cancer cells by activating the NF-κB signal pathway. Single-nucleotide polymorphisms (SNPs) can alter gene function .. Read More»

Genet. Mol. Res. 16(3):
gmr16038826
DOI:
10.4238/gmr16038826
Plant Genetics   Research Article

Cloning and functional characterization of the HbSYR1 gene encoding a syntaxin-related protein in Tibetan hulless barley (Hordeum vulgare L. var. nudum HK. f.)

Authors: Q.J. Xu, Y.L. Wang, Z.X. Wei, H.J. Yuan, X.Q. Zeng and N. Tashi

Tibetan barley is a staple food for the natives of Qinghai-Tibet Plateau. Drought causes a reduction in barley production. In this study, the full-length cDNA of a gene encoding a syntaxin-associated protein was cloned from the leaves of a drought-resistant variety of barley, “Himalaya 10”; its expression was evalu.. Read More»

Genet. Mol. Res. 16(3):
gmr16038909
DOI:
10.4238/gmr16038909
Human Genetics   Research Article

Mac-1 deficiency induces respiratory failure by affecting type I alveolar epithelial cells

Authors: J. Wang, Y.B. Ci, C.L. Liu and H.M. Sun

As a β2 integrin family member, Mac-1 plays an important role in the inflammatory response. Inflammation and lung injury are closely associated, but the involvement of Mac-1 in the occurrence and development of such pathologies remains poorly understood. We aimed to investigate the relationship between Mac-1 deficiency an.. Read More»

Genet. Mol. Res. 16(3):
gmr16039045
DOI:
10.4238/gmr16039045
Human Genetics   Research Article

Suppression of the biological activity of neuroglioma cells by down-regulation of miR-1

Authors: Y.Q. Wang, Y. Cai and X.M. Zhong

Neuroglioma is associated with high rates of malignancy, metastasis, and recurrence. Recently, research on the roles of microRNAs (miR) in cancer prognosis has formed an important area of research as differential expression of miRNAs has been observed in different cancers. However, the detailed mechanism by which miRNAs regula.. Read More»

Genet. Mol. Res. 16(3):
gmr16039256
DOI:
10.4238/gmr16039256
Plant Genetics   Research Article

Genetic diversity in a Poincianella pyramidalis (Tul.) L.P. Queiroz population assessed by RAPD molecular markers

Authors: K.S. Belarmino, M.M. R�ªgo, R.L.A. Bruno, G.D.A. Medeiros,A.P. Andrade and E.R. R�ªgo

Poincianella pyramidalis (Tul.) L.P. Queiroz is an endemic Caatinga (Brazilian savannah biome) species that has been exploited for different purposes, although information is necessary about still existing natural populations. The objective of this study was to evaluate the genetic diversity among 20 P. pyramidalis individuals.. Read More»

Genet. Mol. Res. 16(3):
gmr16039663
DOI:
10.4238/gmr16039663
Microbial Genetics   Research Article

Population genetic structure of three species in the genus Astrocaryum G. Mey. (Arecaceae)

Authors: N.P. Oliveira, M.S.P. Oliveira, L.C. Davide and S. Kalisz

We assessed the level and distribution of genetic diversity in three species of the economically important palm genus Astrocaryum located in Pará State, in northern Brazil. Samples were collected in three municipalities for Astrocaryum aculeatum: Belterra, Santarém, and Terra Santa; and in two municipalities for .. Read More»

Genet. Mol. Res. 16(3):
gmr16039676
DOI:
10.4238/gmr16039676
Plant Genetics   Research Article

Molecular mapping and candidate gene analysis for resistance to powdery mildew in Cucumis sativus stem

Authors: P.N. Liu, H. Miao, H.W. Lu, J.Y. Cui, G.L. Tian, T.C. Wehner, X.F. Gu and S.P. Zhang

Powdery mildew (PM) of cucumber (Cucumis sativus), caused by Podosphaera xanthii, is a major foliar disease worldwide and resistance is one of the main objectives in cucumber breeding programs. The resistance to PM in cucumber stem is important to the resistance for the whole plant. In this study, genetic analysis and gene map.. Read More»

Genet. Mol. Res. 16(3):
gmr16039680
DOI:
10.4238/gmr16039680