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Animal Genetics   Research Article

Molecular characterization and expression patterns of the big defensin gene in freshwater mussel (Hyriopsis cumingii)

Authors: G.-L. Wang, X.-L. Xia, X.-L. Li, S.-J. Dong and J.-L. Li

Antimicrobial peptides (AMPs), of which big defensins are examples, are an important component of the natural defenses of most living organisms, and possess remarkable microbicidal activities. In the present study, using expressed-sequence tag sequences from a cDNA library and RACE, the full-length cDNA sequence of the big def.. Read More»

Genet. Mol. Res. 13(1):
2014.January.29.1
DOI:
10.4238/2014.January.29.1
Human Genetics   Research Article

Single nucleotide polymorphisms in Brahman steers and their association with carcass and tenderness traits

Authors: T. Smith M.G. Thomas T.D. Bidner J.C. Paschal D.E. Franke

Data from purebred Brahman steers (N = 467) were used to study the association of single nucleotide polymorphisms (SNP) with carcass traits and measures of tenderness. Fall weaned calves were grazed and fed in a subtropical environment and then harvested for processing in a commercial facility. Carcass data were recorded 24 h .. Read More»

Genet. Mol. Res. 8(1):
vol8-1gmr537
DOI:
10.4238/vol8-1gmr537
Plant Genetics   Research Article

The role of disulfide bridges in the 3-D structures of the antimicrobial peptides gomesin and protegrin-1: a molecular dynamics study

Authors: J.R.M. Castro, C.A. Fuzo, L. Degr�¨ve and A. Caliri

Some antimicrobial peptides have a broad spectrum of action against many different kinds of microorganisms. Gomesin and protegrin-1 are examples of such antimicrobial peptides, and they were studied by molecular dynamics in this research. Both have a β-hairpin conformation stabilized by two disulfide bridges and are active against gram-positive and g.. Read More»

Genet. Mol. Res. 7(4):
vol7-4gmr507
DOI:
10.4238/vol7-4gmr507
Cytogenomics   Research Article

Mapping of AFLP loci linked to tolerance to cowpea golden mosaic virus

Authors: M.A. Rodrigues C.A.F. Santos J.R.F. Santana

AFLP markers combined with the bulk segregant analysis methodology was used for the identification of molecular markers associated with the cowpea golden mosaic virus (CGMV) resistance gene in 286 F2 cowpea plants derived from the cross IT97K-499-35 x Canapu T16. Segregation data in the F2 population demonstrated that tolerance to CGMV is controlled by a sin.. Read More»

Genet. Mol. Res. 11(4):
2012.August.17.12
DOI:
10.4238/2012.August.17.12
Medical Genetics   Research Article

Clinical effects and safety review of self-expanding stent surgery for extracranial carotid artery stenosis treatment

Authors: Q.F. Zhu, S.Z. Fang, G.F. Wang, Z.Z. Zhou, S.C. Bian, S.D. Cui, S.B. Yu, F.W. Wang, L.B. Shan and J. Kang

This study aimed to investigate the clinical effects and safety review of self-expanding stent surgery in the treatment of extracranial carotid artery stenosis. Seventy-eight patients with carotid artery stenosis were applied with the self-expanding stent for endovascular interventional therapy. Eighty-one stents were implante.. Read More»

Genet. Mol. Res. 13(3):
2014.July.7.5
DOI:
10.4238/2014.July.7.5
Animal Genetics   Research Article

Decoherence in yeast cell populations and its implications for genome-wide expression noise

Authors: M.R.S. Briones F. Bosco

Gene expression “noise” is commonly defined as the stochastic variation of gene expression levels in different cells of the same population under identical growth conditions. Here, we tested whether this “noise” is amplified with time, as a consequence of decoherence in global gene expression profiles (.. Read More»

Genet. Mol. Res. 8(1):
vol8-1gmr531
DOI:
10.4238/vol8-1gmr531
Animal Genetics   Research Article

Matrix-assisted laser desorption ionization-time of flight mass spectrometry analysis of Escherichia coli categories

Authors: C.B. Dallagassa, L.F. Huergo, M.I. Stets, F.O. Pedrosa, E.M. Souza, L.M. Cruz, F.E.A. Assis, S. Wolf, W. Volanski, G. Picheth, C.P. Pigatto-Denardi, S.M.S.S. Farah and C.M.T. Fadel-Picheth

The mass profiles of cell-free extracts of 180 commensal and pathogenic strains of Escherichia coli were determined by MALDI-TOF mass spectrometry (MS). While some peaks were highly conserved in all E. coli, several peaks occurred only in some strains, showing heterogeneity among them. We did not detect strain-specific peaks f.. Read More»

Genet. Mol. Res. 13(1):
2014.January.29.2
DOI:
10.4238/2014.January.29.2
Human Genetics   Research Article

Hypertension-mediated enhancement of JNK activation in association with endoplasmic reticulum stress in rat model hippocampus with cerebral ischemia-reperfusion

Authors: Y.N. Zhao, J.M. Li, C.X. Chen, P. Zhang and S.X. Li

Acute brain ischemia can induce the activation of c-Jun N-terminal kinases (JNKs). Hypertension is a critical etiology for brain ischemia. We identified the effects of hypertension on the activation of JNK as well as its impact on SP600125, a JNK inhibitor, during endoplasmic reticulum stress (ERS) in the hippocampus using a rat model. Transient whole-brain .. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.21.10
DOI:
http://dx.doi.org/10.4238/2015.September.21.10
Plant Genetics   Research Article

Oxidative stress proteins as an indicator of a low quality of eucalyptus clones for the pulp and paper industry

Authors: D.S. Britto C.P. Pirovani E.R. Gonzalez J.F. Silva A.S. Gesteira J.C.M. Cascardo

Eucalyptus is a genus widely cultivated in many tropical and subtropical regions of the world as one of the main sources of raw materials for the pulp and paper industry. Identification of clones and selection of genotypes with desirable agronomic characteristics would be useful. We assessed eucalyptus full-sibs that varied in wood quality, using a combinati.. Read More»

Genet. Mol. Res. 11(4):
2012.August.17.13
DOI:
10.4238/2012.August.17.13
Plant Genetics   Research Article

Development and characterization of microsatellite loci for Ocotea species (Lauraceae) threatened with extinction

Authors: E.M. Martins, G. Martinelli, M.P. Arbetman, R.W. Lamont, J.L. Sim�µes-Ara�ºjo, D. Powell, M. Ciampi-Guillardi, C. Baldauf, A. Quinet, P. Galisa and A. Shapcott

The Atlantic rainforest species Ocotea catharinensis, Ocotea odorifera, and Ocotea porosa have been extensively harvested in the past for timber and oil extraction and are currently listed as threatened due to overexploitation. To investigate the genetic diversity and population structure of these sp.. Read More»

Genet. Mol. Res. 13(3):
2014.July.7.6
DOI:
10.4238/2014.July.7.6