Analysis of thyroid peroxidase antibody in early pregnancy
Authors: L. Lin, X.L. Zhang and Y. Long
This study aimed to investigate the thyroid peroxidase antibody (TPOAb) positive rate and how TPOAb affects thyroid function between 7 and 12 weeks of gestation. Six hundred and eleven cases of healthy primipara were enrolled in this study between September 2010 and June 2011, and all of them were given a regular prenatal chec.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.7.3
- DOI:
- 10.4238/2014.July.7.3
Transcriptome analysis and anthocyanin-related genes in red leaf lettuce
Authors: Y.Z. Zhang*, S.Z. Xu*, Y.W. Cheng, H.Y. Ya and J.M. Han
This study aimed to analyze the transcriptome profile of red lettuce and identify the genes involved in anthocyanin accumulation. Red leaf lettuce is a popular vegetable and popular due to its high anthocyanin content. However, there is limited information available about the genes involved in anthocyanin biosynthesis in this species. In this study, trans.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017023
- DOI:
- 10.4238/gmr.15017023
Expression of the luteinizing hormone receptor (LHR) gene in ovine non-gonadal tissues during estrous cycle
Authors: L.H. Wang W. Zhang Q.X. Gao F. Wang
Luteinizing hormone (LH) is an important glycoprotein hormone that regulates gonadal function in mammals and in turn regulates physiological status changes during the estrous cycle. The function of LH is mediated by luteinizing hormone receptor (LHR). In order to examine the expression patterns of the LHR gene in non-gonadal tissues during the 4 phases of.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.15.8
- DOI:
- 10.4238/2012.October.15.8
Identification of copy number variation in the gene for autosomal dominant optic atrophy, OPA1, in a Chinese pedigree
Authors: X. Jin, Y.H. Chen, Z. Liu, Y. Deng, N.N. Li, H. Huang, M. Qi, X. Yi and J. Zhu
Autosomal dominant optic atrophy (ADOA) is an optic neuropathy characterized by bilateral optic nerve pallor and decreased visual acuity. It has been reported to be associated with two genes, OPA1, OPA3, and the OPA4, OPA5, and OPA8 loci. However, mutationsin OPA1 constitute the most prevalent cause of ADOA. The purpose of this study was to identify the u.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.21.8
- DOI:
- http://dx.doi.org/10.4238/2015.September.21.8
Wnt/�²-catenin aids in regulating the proliferation of hepG2 cells mediated by thy-1
Authors: B.Q. Cheng, Y. Jiang, Q. Zhu and W.G. Lin
Cancer stem cells have been found to play important roles in carcinoma. Although thy-1 has been identified as a potential stem cell marker of liver cancer, whether the Wnt/β-catenin signaling pathway plays an important role in regulating hepatocarcinoma proliferation and apoptosis mediated by thy-1 remains unknown. Our re.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.7.4
- DOI:
- 10.4238/2014.July.7.4
Association between V4 polymorphism in the ADAM33 gene and asthma risk: a meta-analysis
Authors: W. Zheng, L. Wang, X. Su and X.F. Hu
In this study, we evaluated the associations between the V4 (rs2787094 G>C) polymorphism in a disintegrin and metalloproteinase domain 33 (ADAM33) gene and asthma risk. We searched Web of Science, PubMed, Google Scholar, EBSCO, Cochrane Library, and CBM databases from inception through August 2013, without language restrictions. Meta-analysis was perfo.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.6.2
- DOI:
- 10.4238/2015.February.6.2
A missense mutant of the PPAR-�³gene associated with carcass and meat quality traits in Chinese cattle breeds
Authors: Y.Y. Fan G.W. Fu C.Z. Fu L.S. Zan W.Q. Tian
The peroxisome proliferator-activated receptor gamma (PPAR-Ã?³) is a key molecule in adipocyte differentitation; it transactivates multiple target genes in lipid metabolic pathways. Using PCR-SSCP and DNA sequencing, we evaluated a potential association of an SNP (72472 Gï¹¥T in exon7) of the bovine PPAR-Ã?³gene with carcass and meat quality traits in 6.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.August.17.4
- DOI:
- 10.4238/2012.August.17.4
Genetic diversity in somatic mutants of grape (Vitis vinifera) cultivar Italia based on random amplified polymorphic DNA
Authors: S.H.Z. Maia C.A. Mangolin S.A.O. Collet M.F.P.S. Machado
Random amplified polymorphic DNA (RAPD) markers were used to detect polymorphism and to examine relationships among four table grape clones from northwestern Paraná, in southern Brazil. The 10 primers used for RAPD fingerprints generated 126 reproducible fragments, of which 63, 68, 76, and 72 were polymorphic in cultiva.. Read More»
- Genet. Mol. Res. 8(1):
- vol8-1gmr536
- DOI:
- 10.4238/vol8-1gmr536
Genetic analyses of the major and minor locus groups of bacterial wilt resistance in tobacco using a diallel cross design
Authors: Y.L. Qian1*, J. Chen2*, J.J. Dong3, Z.C. Wu4, Y.H. Liu3, B.Y. Xue3, F.W. Shao3 and X.Y. Sun1
Tobacco germplasm samples with various levels of resistance to bacterial wilt were selected to construct F1 combinations of parental inbred lines and orthogonal diallel crosses using samples collected in 2009 (15 germplasms), 2010 (15 germplasms), and 2011 (16 germplasms). A total of 1/2P (P + 1) experimental materials were used for analysis. Based on the.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017223
- DOI:
- 10.4238/gmr.15017223
Decreased MEFV gene expression in rheumatoid arthritis patients
Authors: E.O. Etem, S.S. Koca, D. Erol, S. Yolbas, E. Oz, H. Elyas and A. Is�±k
Rheumatoid arthritis (RA) is a major cause of adult chronic inflammatory arthritis and an autoimmune disease of unknown etiology in which the inflammatory pathology involves T cell activation. Genetic mutations in the Mediterranean fever (MEFV) gene, encoding pyrin, influence the severity of RA, but the underlying mechanisms are not completely understood... Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.6.3
- DOI:
- 10.4238/2015.February.6.3