Genetic diversity of natural populations of Anemopaegma arvense (Bignoniaceae) in the Cerrado of S�£o Paulo State, Brazil
Authors: A.P. Batistini, M.P.C. TellesB.W. BertoniJ. da S. Coppede F.V. M�´ro, S. de C. Fran�§a, A.M.S. Pereira
Catuaba (Anemopaegma arvense), a Bignoniaceae species endemic to Cerrado regions, shows anticancer properties and is widely used as a stimulant in traditional medicine. We evaluated the genetic diversity of seven populations found in the State of São Paulo, using random amplified polymorphic DNA markers. After optimizat.. Read More»
- Genet. Mol. Res. 8(1):
- vol8-1gmr538
- DOI:
- 10.4238/vol8-1gmr538
Genetic characterization and evaluation of anthropogenic impacts on genetic patterns in cultured and wild populations of mussels (Mytilus galloprovincialis) from Greece
Authors: I.A. Giantsis N. Kravva A.P. Apostolidis
Despite the great commercial and economic importance of mussels, Mytilus galloprovincialis (Bivalvia, Mollusca) in Greece, little information is available concerning their population genetic structure. We used RAPD markers to examine genetic differentiation and potential impact of aquaculture practices and other anthropogenic activities on the genetic str.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.August.17.14
- DOI:
- 10.4238/2012.August.17.14
Global gene expression profile in myelodysplastic syndromes using SAGE
Authors: C.F. Mendiburu, W.A. Silva Jr., O. Ricci Jr., C.R. Bonini-Domingos and A.C. Fett-Conte
The molecular pathogenesis of myelodysplastic syndromes (MDS) is poorly understood. In order to expand our knowledge of genetic defects in MDS, we determined the overall profile of genes expressed in bone marrow from patients with refractory anemia with excess blasts (RAEB) by serial analysis of gene expression (SAGE). The present report describes a parti.. Read More»
- Genet. Mol. Res. 7(4):
- vol7-4gmr521
- DOI:
- 10.4238/vol7-4gmr521
Effect of Moringa oleifera on advanced glycation end-product formation and lipid metabolism gene expression in HepG2 cells
Authors: W. Sangkitikomol, A. Rocejanasaroj and T. Tencomnao
In Thai traditional medicine, Moringa oleifera is used for the treatment of diabetes and hyperlipidemia. Oxidative stress plays a major role in the pathogenesis of many degenerative diseases, such as hyperlipidemia, diabetes mellitus, and cardiovascular disease. We evaluated the antioxidant effect of M. oleifera extract (MOE) .. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.29.3
- DOI:
- 10.4238/2014.January.29.3
Evaluation of cancer records from 2000-2004 in Denizli, Turkey
Authors: A. K�¶ksal H.��. Sorkun H. Demirhan A.G. Tomatir T. Alan F. ��zerdem
Objective information about cancer incidence is important for planning control programs. We examined the distribution of cancer cases recorded in Denizli province, Turkey. A total of 2185 cancer cases reported to the Denizli Province Health Ministry’s Cancer Early Diagnosis Center during the years 2000-2004 were evaluate.. Read More»
- Genet. Mol. Res. 8(1):
- vol8-1gmr533
- DOI:
- 10.4238/vol8-1gmr533
LEPR p.Q223R, �²3-AR p.W64R and LEP c.-2548G>A gene variants in obese Brazilian subjects
Authors: Duarte SFP, Francischetti EA, Genelhu VA, Cabello PH and Pimentel MMG
Obesity is due to the combined effects of genes, environment, lifestyle, and the interactions of these factors. The adrenergic receptor β3 (β3-AR), leptin (LEP) and leptin receptor (LEPR) genes have been intensively evaluated in the search of variants that could be related to obesity and its cardiometabolic complicat.. Read More»
- Genet. Mol. Res. 6(4):
Transcriptional analysis of atrial and ventricular muscles from rats
Authors: Y. Zhi3*, Z. Cao2*, Q.H. Li1, X.L. Li1, Y. Sun1, T. Zhang1 and Q. Zhang1
Previous studies have used microarray technology to explore gene expression differences between the atrium and the ventricle. However, selection criteria for the differentially expressed genes (DEGs) based only on either the fold change or the P value in these studies. Here, we aim to further identify the DEGs by setting a P value threshold of 2, which ma.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017330
- DOI:
- 10.4238/gmr.15017330
COL1A1 gene -1997G/T polymorphism and risk of osteoporosis in postmenopausal women: a meta-analysis
Authors: K.H. Yu, J. Tang, C.Q. Dai, Y. Yu and J.J. Hong
Studies investigating the association between the COL1A1 gene -1997G/T polymorphism and the risk of osteoporosis in postmenopausal women have reported conflicting results. We performed a meta-analysis based on the evidence currently available from the literature to make a more precise estimation of this relationship. We conducted searches of the published.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.21.11
- DOI:
- http://dx.doi.org/10.4238/2015.September.21.11
An improved extraction protocol for metagenomic DNA from a soil of the Brazilian Atlantic Rainforest
Authors: J.H. Amorim, T.N.S. Macena, G.V. Lacerda-Junior, R.P. Rezende, J.C.T. Dias, M. Brendel and J.C.M. Cascardo
The need for the prospecting for and identification of new biomolecules is a reality. Molecular techniques allow access to the metabolic potential of microorganisms via the isolation of DNA from environmental samples, i.e., without the application of microbial culture techniques. With its great biological diversity, the Atlantic Rainforest biome has a soi.. Read More»
- Genet. Mol. Res. 7(4):
- vol7-4gmr509
- DOI:
- 10.4238/vol7-4gmr509
Does copper stress lead to spindle misposition-dependent cell cycle arrest?
Authors: C. Tarhan A.T. Sarikaya
Because of its specific electrochemical properties, copper is an essential heavy metal for living organisms. As with other heavy metals, high levels can provoke damage. We examined gene expression under copper stress in wild-type fission yeast (Schizosaccharomyces pombe) through differential display. After the EC50 concentration of CuSO4 was determined as 50.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.25.1
- DOI:
- 10.4238/2012.October.25.1