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Medical Genetics   Research Article

Association of peroxisome proliferator-activated receptor-delta polymorphisms with sugar metabolism indices and tumor necrosis factor alpha level

Authors: X.J. Yu, B.L. Su, X.M. Wang, H.J. Feng and C.J. Jin

This study aims to investigate the association of peroxisome proliferator-activated receptor (PPAR) delta -87T/C polymorphism with several sugar metabolism indices and tumor necrosis factor α (TNF α) level. The body mass index (BMI), waist size, and levels of fasting plasma glucose, serum lipid, fasting insulin, TN.. Read More»

Genet. Mol. Res. 13(3):
2014.July.7.1
DOI:
10.4238/2014.July.7.1
Microbial Genetics   Research Article

Cross-reactivity of anti-human cytokine monoclonal antibodies used as a tool to identify novel immunological biomarkers in domestic ruminants

Authors: C.S. Bao, L. Liu, B. Wang, X.-G. Xia, Y.J. Gu, D.J. Li, S.L. Zhan,G.L. Chen and F.B. Yang

Eleven commercially available PE-labeled anti-human (IL-1-α, IL-6, IL-8, TNF-α, IL-17A, IL-5, IL-10, IL-12 and IL-13) and anti-mouse (IL-10, TNF-α) cytokine monoclonal antibodies (mAbs) were tested for cross-reactivity with cattle, goat, and sheep cytokines. Cross-reactivity was assessed by comparative analysis with the standard reactivi.. Read More»

Genet. Mol. Res. 14(1):
2015.February.3.2
DOI:
10.4238/2015.February.3.2
Plant Genetics   Research Article

Chromosome instability in industrial strains of Saccharomyces cerevisiae batch cultivated under laboratory conditions

Authors: Lucena BTL, Silva-Filho EA, Coimbra MRM, Morais JOF, Simoes DA and Morais Jr. MA

Industrial ethanol fermentation is a complex microbiological process to which yeast cells must adapt for survival. One of the mechanisms for adaptation is thought to involve chromosome rearrangements. We found that changes in chromosome banding patterns measured by pulsed-field gel electrophoresis can also be produced in labor.. Read More»

Genet. Mol. Res. 6(4):
Animal Genetics   Research Article

Association of single nucleotide polymorphisms in the bovine leptin and leptin receptor genes with growth and ultrasound carcass traits in Nellore cattle

Authors: R.C.G. da Silva J.B.S. Ferraz F.V. Meirelles J.P. Eler J.C.C. Balieiro D.C. Cucco E.C. Mattos F.M. Rezende S.L. Silva

Given the important role of leptin in metabolism, we looked for a possible association of leptin and leptin receptor polymorphisms with carcass and growth traits in Nellore cattle. We examined associations of leptin and leptin receptor SNPs with ultrasound carcass (longissimus dorsi muscle area (ribeye area), backfat thickness and rump fat thickness and grow.. Read More»

Genet. Mol. Res. 11(4):
2012.August.17.10
DOI:
10.4238/2012.August.17.10
Animal Genetics   Research Article

Sequence analysis of the S1PR1 gene in river buffalo

Authors: N.B. Stafuzza1,2, B.C.M. Naressi1, M.M. Borges1 and M.E.J. Amaral-Trusty1

Recent developments in methodologies for genomic analyses have enabled a significant advance in understanding of the river buffalo genome. The S1PR1 gene has been mapped to buffalo chromosome 6 and bovine chromosome 3; this gene is of interest as it is a candidate for marbling in meat, an important economic trait. Here, we performed next generation sequen.. Read More»

Genet. Mol. Res. 15(1):
gmr.15016363
DOI:
10.4238/gmr.15016363
Human Genetics   Research Article

Craniocervical decompression with duraplasty and cerebellar tonsillectomy as treatment for Chiari malformation-I complicated with syringomyelia

Authors: C.S. Bao, L. Liu, B. Wang, X.-G. Xia, Y.J. Gu, D.J. Li, S.L. Zhan,G.L. Chen and F.B. Yang

This study aimed to investigate the therapeutic effects of craniocervical decompression with duraplasty and cerebellar tonsillectomy for the treatment of Chiari malformation-I with syringomyelia (CM I-SM). From January 2005 to December 2011, 127 patients with CM I-SM underwent craniocervical decompression with duraplasty and cerebellar tonsillectomy and t.. Read More»

Genet. Mol. Res. 14(1):
2015.February.3.2
DOI:
10.4238/2015.February.3.2
Plant Genetics   Research Article

Genomic breeding value prediction for simple maize hybrid yield using total effects of associated markers, under different imbalance levels and environments

Authors: N.F. Cantelmo1, R.G. Von Pinho2 and M. Balestre3

The main objective of a maize breeding program is to generate hybrid combinations that are more productive than those pre-existing in the market. However, the number of parents, and consequently the number of crosses, increases so rapidly that the phenotypic evaluation of all the possible combinations becomes economically and technically infeasible. In th.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017232
DOI:
10.4238/gmr.15017232
Plant Genetics   Research Article

Characterization of nine transferred SSR markers in the tropical tree species Enterolobium contortisiliquum (Fabaceae)

Authors: P.A. Moreira S.A.S. Sousa F.A. Oliveira N.H. Ara�ºjo G.W. Fernandes D.A. Oliveira

Transfer of molecular markers is widely used in conservation genetic studies. We investigated the transferability of simple sequence repeat (SSR) markers developed for Enterolobium cyclocarpum to E. contortisiliquum, a tropical tree widely distributed in dry forests. A set of 9 evaluated SSR markers were amplified in E. contortisiliquum and the degree of .. Read More»

Genet. Mol. Res. 11(4):
2012.August.17.11
DOI:
10.4238/2012.August.17.11
Plant Genetics   Research Article

An optimized mini-preparation method to obtain high-quality genomic DNA from mature leaves of sunflower

Authors: Li JT, Yang J, Chen DC, Zhang XL and Tang ZS

In order to investigate the mutation characteristics and to further examine the genetic variation of mutant sunflower (Helianthus annuus) obtained in plants grown from seeds exposed to space conditions, only the mature tissues such as leaf and flower could be used for DNA extraction after mutation characteristics were confirme.. Read More»

Genet. Mol. Res. 6(4):
Animal Genetics   Research Article

Isolation and characterization of novel polymorphic microsatellite markers for Lutjanus erythropterus

Authors: L.Lin, C.H. Li, S.N. Xu, Y. Liu and Y.Y. Xiao

We isolated and characterized 22 polymorphic microsatellite loci in the crimson snapper (Lutjanus erythropterus) using a (GT)13-enriched genomic library. We found three to 15 alleles per locus, with a mean of 6.68. The observed and expected heterozygosities ranged from 0.087 to 0.978 and from 0.125 to 0.904, respectively, with averages of 0.576 and 0.650,.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.21.5
DOI:
http://dx.doi.org/10.4238/2015.September.21.5