Diversity and genetic structure of mangaba remnants in states of northeastern Brazil
Authors: J.A.E. Amorim, L.R. Mata, A.S. L�©do, V.C.R. Azevedo andA.V.C. Silva
In this study, we analyzed the genetic diversity and structure of remnants of mangaba populations in states of northeastern Brazil by applying 9 microsatellite markers previously developed to establish conservation strategies for germplasm and species preservation. Six to 20 individuals per population were analyzed, with a total of 94 individuals and 6 po.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.2.7
- DOI:
- 10.4238/2015.February.2.7
Small molecule-enrichment analysis in response to osmotic stimuli in the intervertebral disc
Authors: H. Ma Y.Z. Xie J. Zhao B. Ye
The intervertebral disc (IVD) is a heterogeneous structure that contributes to load support and flexibility in the spine. IVD cells experience a broad range of physical stimuli under physiological conditions, including alterations in their osmotic environment. To date, the molecular mechanisms regulating the response of IVD to osmotic pressure are still not .. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.9.2
- DOI:
- 10.4238/2012.October.9.2
Can established cultured papilloma cells harbor bovine papillomavirus?
Authors: S.R.C. Campos1, C. Trindade1, O.P. Ferraz1, D.N.S. Giovanni1, A.A. Lima1,2, H.V.A. Caetano1,3, R.F. Carvalho1,3, E.H. Birgel Jr.4, M.L.Z. Dagli3, E. Mori5, P.E. Brand�£o5, L.J. Richtzenhain5, W. Be�§ak1,6 and R.C. Stocco1
Papillomaviruses have been reported to be very difficult to grow in cell culture. Also, there are no descriptions of cell cultures from lesions of bovine cutaneous papillomatosis, with identification of�� � � � � � � �� different bovine papilloma virus (BPV) DNA sequences. In the present report, we describ.. Read More»
- Genet. Mol. Res. 7(4):
- vol7-4gmr498
- DOI:
- 10.4238/vol7-4gmr498
6-Dimethylaminopurine and cyclohexamide are mutagenic and alter reproductive performance and intrauterine development in vivo
Authors: R.J. Oliveira, M.S. Mantovani, J.R. Pesarini, M.O. Mauro,A.F. da Silva, T.R. Souza and L.R. Ribeiro
The compounds 6-dimethylaminopurine (6-DMAP) and cyclohexamide (CHX) are currently used to stimulate the development of embryos produced by nuclear transfer in the production of cloned mammals with a great deal success. This study investigated the effects of 6-DMAP and CHX in vivo using biological assays to evaluate reproductive performance in females, terat.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.2.8
- DOI:
- 10.4238/2015.February.2.8
Regulation of ATG6/Beclin-1 homologs by abiotic stresses and hormones in rice (Oryza sativa L.)
Authors: R.M. Rana S. Dong Z. Ali J. Huang H.S. Zhang
Autophagy, a complex and conserved mechanism, serving as a defense response in all eukaryotic organisms, is regulated by several proteins, among which ATG proteins are the most important due to their involvement in autophagosome formation. ATG6/Beclin-1 proteins, reported to be essential for autophagosome formation and assigned as a conserved domain, were.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.August.17.3
- DOI:
- 10.4238/2012.August.17.3
Association of miR-149C>T and miR-499A>G polymorphisms with the risk of hepatocellular carcinoma in the Chinese population
Authors: X.H. Wang, F.R. Wang, Y.F. Tang, H.Z. Zou and Y.Q. Zhao
We investigate the potential association of miR-149C>T and miR-499A>G polymorphisms and the risk of hepatocellular carcinoma (HCC). A matched case-control study of 152 cases and 304 controls were conducted. The miR-149C>T and miR-499A>G genotypes were analyzed using duplex polymerase chain reaction with restricted .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.20
- DOI:
- 10.4238/2014.July.4.20
Distribution and clinal trends of the ABO and Rh genes in select Middle Eastern countries
Authors: E.S. AlSuhaibani, N.A. Kizilbash, K. Afshan and S. Malik
An understanding of the ABO and Rh blood group systems is important for blood transfusions and is also pertinent due to their potential association with certain morbidities and susceptibilities to infections. To investigate the diversity and differentiation of the ABO and Rh loci in Middle Eastern populations, data from twelve representative Middle Easter.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.9.12
- DOI:
- http://dx.doi.org/10.4238/2015.September.9.12
Protective effect and mechanism of hydrogen treatment on lung epithelial barrier dysfunction in rats with sepsis
Authors: L.-D. Liu, X.-Y. Wu, B.-D. Tao, N. Wang and J. Zhang
This study aimed to explore the protective effect of hydrogen and to investigate the underlying mechanism of its preliminary effect on the alveolar epithelial barrier function in septic rats. Forty-five male Sprague-Dawley rats were divided randomly into three groups (N = 15): control [saline injection (intraperitoneal, ip), air drawing; SA], acute lung i.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016050
- DOI:
- 10.4238/gmr.15016050
Association between SNPs in genes involved in folate metabolism and preterm birth risk
Authors: B.J. Wang, M.J. Liu, Y. Wang, J.R. Dai, J.Y. Tao, S.N. Wang,N. Zhong and Y. Chen
We investigated the association between 12 single nucleotide polymorphisms (SNPs) in 11 genes involved in folate metabolic and preterm birth. A subset of SNPs selected from 11 genes/loci involved in the folic acid metabolism pathway were subjected to SNaPshot analysis in a case-control study. Twelve SNPs (CBS-C699T, DHFR-c594+59del19, GST01-C428T, MTHFD-G.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.2.9
- DOI:
- 10.4238/2015.February.2.9
Isolation and characterization of the Chrysanthemum nitrate transporter CmNRT1
Authors: C.S. Gu, X.X. Zhang, S.M. Chen, T. Li, Y. Chen, J.F. Jiang and F.D. Chen
In this study, the nitrate transporter gene CmNRT1 was isolated from the chrysanthemum variety ‘Nannongxuefeng’. The full-length cDNA contains an open reading frame of 1761 bp encoding 587 residues. Using qRT-PCR, we found that CmNRT1 was induced by 10 mM NO3- in roots and shoots. Two Arabidopsis thaliana transgenic plants expressing CmNRT1 we.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017148
- DOI:
- 10.4238/gmr.15017148