BNDb - Biomolecules Nucleus Database: an integrated proteomics and transcriptomics database
Authors: Faria-Campos AC, Gomes RR, Moratelli FS, Rausch-Fernandes H, Franco GR and Campos SVA
Proteomics correspond to the identification and quantitative analysis of proteins expressed in different conditions or life stages of a cell or organism. Methods used in proteomics analysis include mainly chromatography, two-dimensional electrophoresis and mass spectrometry. Data generated in proteomics analysis vary significa.. Read More»
- Genet. Mol. Res. 6(4):
Genetic variability analysis of Zymomonas mobilis strains from the UFPEDA microorganisms collection
Authors: L.C.N. Silva, J.M. Ara�ºjo, J.L. Azevedo, R.J.S.A. Padilha and R. Yara
Zymomonas mobilis is a Gram-negative bacterium that has drawn attention in the bioethanol industry. Besides bioethanol, this bacterium also produces other biotechnological products such as levans, which show antitumor activity. Molecular studies involving Z. mobilis have advanced to the point that allows us to characterize interspecies genetic diversity a.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.2.5
- DOI:
- 10.4238/2015.February.2.5
Gene expression profiling of epithelial ovarian cancer reveals key genes and pathways associated with chemotherapy resistance
Authors: M. Zhang and S.C. Luo
The aim of this study is to analyze gene expression data to identify key genes and pathways associated with resistance to platinum-based chemotherapy in epithelial ovarian cancer (EOC) and to improve clinical treatment strategies. The gene expression data set was downloaded from Gene Expression Omnibus and included 12 chemotherapy-resistant EOC samples an.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017496
- DOI:
- 10.4238/gmr.15017496
RAPD fingerprint construction and genetic similarity of Mesona chinensis (Lamiaceae) in China
Authors: G.F. Zhang J.M. Guan X.P. Lai J. Lin J.M. Liu H.H. Xu
Mesona chinensis is an economically important agricultural crop, primarily cultivated for making grass jelly. It was originally discovered in South China. We examined 18 cultivars, including cultivars from Guangdong, Fujian, and Guangxi, China, Taiwan, and Indonesia, and a hybrid (a cross between cultivars from Indonesia and Guangdong), based on RAPD mark.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.4.12
- DOI:
- 10.4238/2012.October.4.12
Identification of EeSt-genome species in Pseudoroegneria and Elytrigia (Poaceae:Triticeae) by using SCAR markers from ITS sequences
Authors: Z.H. Tao and L. Yin
To detect EeSt-genome species in Pseudoroegneria and Elytrigia, the primers ES45 (5'-GTAGGCGACGGTTTTCA-3') and ES261 (5'-TCGCTACGTTCTTCATC-3') were designed as sequence characterized amplified region markers based on the 6-base pair indel in internal transcribed spacer 1 (ITS1) regions and conserved sites in the 5.8S regions, respectively. Polymerase chai.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.2.6
- DOI:
- 10.4238/2015.February.2.6
Brazilian Nelore cattle: a melting pot unfolded by molecular genetics
Authors: M.A.C. Dani1, M.B. Heinneman2 and S.U. Dani1
The aim of the present article was to study the population structure and genetic diversity of Nelore cattle and genetic relationships between Nelore and different taurine and zebu breeds raised in Brazil. DNA polymorphism analysis was carried out with 1976 animals of 16 zebu, taurine and synthetic breeds raised in Brazil. A higher genetic differentiation .. Read More»
- Genet. Mol. Res. 7(4):
- vol7-4gmr499
- DOI:
- 10.4238/vol7-4gmr499
Mitochondrial haplogroup D4 confers resistance and haplogroup B is a genetic risk factor for high-altitude pulmonary edema among Han Chinese
Authors: Y.J. Luo W.X. Gao S.Z. Li X.W. Huang Y. Chen F.Y. Liu Q.Y. Huang Y.Q. Gao
High-altitude pulmonary edema (HAPE) is a life-threatening condition caused by acute exposure to high altitude. Accumulating evidence suggests that genetic factors play an important role in the etiology of HAPE. However, conclusions from association studies have been hindered by limited sample size due to the rareness of this disease. It is known that mitoch.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.9.1
- DOI:
- 10.4238/2012.October.9.1
Molecular genetic analysis of heterosis in interspecific hybrids of Argopecten purpuratus x A. irradians irradians
Authors: L.P. Hu, X.T. Huang, Y. Sun, J.X. Mao, S. Wang, C.D. Wang and Z.M. Bao
Argopecten purpuratus and Argopecten irradians irradians hybridization was successfully performed and the hybrid offspring displayed apparent heterosis in growth traits. To better understand the genetic basis of heterosis, the genomic composition and genetic variation of the hybrids were analyzed with amplified fragment length polymorphism (AFLP) and simp.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.9.9
- DOI:
- http://dx.doi.org/10.4238/2015.September.9.9
Computational prediction and experimental validation of a novel miRNA in Suaeda maritima, a halophyte
Authors: S.A. Gharat and B.P. Shaw
The lack of available transcriptome data for plants of no economic or agronomic importance limits the identification of miRNAs in many species. Considering the possible similarity of the transcriptome between related species, the present study used expressed sequence tags (ESTs) of Suaeda salsa and Suaeda glauca to identify conserved miRNAs, which were va.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017527
- DOI:
- 10.4238/gmr.15017527
Electrostatic potential calculation for biomolecules - creating a database of pre-calculated values reported on a per residue basis for all PDB protein structures
Authors: Rocchia W and Neshich G
STING and JavaProtein Dossier provide a collection of physical-chemical parameters, describing protein structure, stability, function, and interaction, considered one of the most comprehensive among the available protein databases of similar type. Particular attention in STING is paid to the electrostatic potential. It makes u.. Read More»
- Genet. Mol. Res. 6(4):