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Medical Genetics   Research Article

Genetic affinities of central China populations.

Authors: H.Y. Zhou, H.W. Wang, S.N. Tan, Y. Chen, W.L. Wang, H.X. Tao, Z.C. Yin, Y.H. Zou, S.M. Ouyang and B. Ni

Hunan locates in the south-central part of China, to the south of the middle reaches of the Yangtze River and south of Lake Dongting. According to the historical records, the peopling of Hunan by modern human ancestors can ascend to 40 thousand years ago. Thus, to trace the ancient maternal components can offer further insight.. Read More»

Genet. Mol. Res. 13(1):
http://dx.doi.org/2014.January.28.7
DOI:
http://dx.doi.org/10.4238/2014.January.28.7
Plant Genetics   Research Article

Construction and analysis of a suppression subtractive hybridization library of regeneration-related genes in soybean

Authors: J. Sun, J. Li, M. Liu, B.B. Zhang, D.M. Li, M. Wang, C. Zhang,W.B. Li, A.Y. Su and X.X. Wu

The development of a genetic transformation system is needed to address the problem of the low efficiency associated with soybean regeneration. To contribute to the enhancement of the soybean regenerative capacity, we explored the developmental mechanisms of soybean regeneration at the molecular level using a suppression subtractive hybridization cDNA librar.. Read More»

Genet. Mol. Res. 14(1):
2015.January.30.20
DOI:
10.4238/2015.January.30.20
Medical Genetics   Research Article

TGF-?²1 polymorphism 509 C>T is associated with an increased risk for hepatocellular carcinoma in HCV-infected patients

Authors: J. Ma, Y.C. Liu, Y. Fang, Y. Cao and Z.L. Liu

Transforming growth factor-beta 1 (TGF-β1), a member of the transforming growth factor beta family, functions as a multi-functional cytokine and plays a key role in cellular growth, proliferation, and differentiation. The 509 C/T polymorphism in the TGF-β1 gene has been implicated in the outcome of hepatitis C virus (HCV) infection; however, lit.. Read More»

Genet. Mol. Res. 14(2):
2015.May.4.3
DOI:
10.4238/2015.May.4.3
Human Genetics   Research Article

Meta-analysis of epidemiological studies demonstrates significant association of PTGS2 polymorphism rs689470 and no significant association of rs20417 with prostate cancer

Authors: H.-T. Zhang, Y. Xu, Z.-H. Zhang and L. Li

Evidence is accumulating that chronic inflammation has an important role in prostate cancer. Two common polymorphisms in the prostaglandin-endoperoxide synthase 2 (PTGS2) gene, rs20417 and rs689470, have been found to alter the risk for prostate cancer, but the various studies are not in agreement. To derive a more precise est.. Read More»

Genet. Mol. Res. 11(2):
2012.June.15.13
DOI:
10.4238/2012.June.15.13
Plant Genetics   Research Article

Effect of selective logging on genetic diversity and gene flow in Cariniana legalis sampled from a cacao agroforestry system.

Authors: J.B. Leal, R.P. Santos and F.A. Gaiotto

The fragments of the Atlantic Forest of southern Bahia have a long history of intense logging and selective cutting. Some tree species, such as jequitibá rosa (Cariniana legalis), have experienced a reduction in their populations with respect to both area and density. To evaluate the possible effects of selective loggin.. Read More»

Genet. Mol. Res. 13(1):
2014.January.28.8
DOI:
10.4238/2014.January.28.8
Animal Genetics   Research Article

Bee communities (Hymenoptera: Anthophila) of the â??Cerradoâ? ecosystem in S?£o Paulo State, Brazil

Authors: S.R. Andena F.S. Nascimento P.C. Bispo M.R. Mechi S. Mateus L.R. Bego

Five surveys of the bee communities in four “Cerrado” ecosystem reserves in São Paulo State were compared for species richness and similarity. These areas are fragment vegetation reser­ves located in the Cerrado Corumbataí Reserve (Corumbataí), Jataí Ecological Park (Luiz Antôn.. Read More»

Genet. Mol. Res. 8(2):
vol8-2kerr009
DOI:
10.4238/vol8-2kerr009
Plant Genetics   Research Article

Genome-wide analysis and identification of KT/HAK/KUP potassium transporter gene family in peach (Prunus persica)

Authors: Z.Z. Song, R.J. Ma and M.L. Yu

The KT/HAK/KUP family members encoding high-affinity potassium (K+) transporters mediate K+ transport across the plasma membranes of plant cells to maintain plant normal growth and metabolic activities. In this paper, we identified 16 potassium transporter genes in the peach (Prunus persica) using the Hidden Markov model scanning strategy and searching th.. Read More»

Genet. Mol. Res. 14(1):
2015.January.30.21
DOI:
10.4238/2015.January.30.21
Human Genetics   Research Article

Association of genetic polymorphisms in TERT-CLPTM1L with lung cancer in a Chinese population

Authors: S.G. Liu, L. Ma, Q.H. Cen, J.S. Huang, J.X. Zhang and J.J. Zhang

Genome-wide association studies in several ethnic groups have reported that polymorphisms of the telomerase reverse transcriptase (TERT) and cleft lip and palate transmembrane 1-like (CLPTM1L) genes, located on 5p15.33, are associated with susceptibility to lung cancer. However, whether genetic variants of TERT-CLPTM1L are associated with an increased ris.. Read More»

Genet. Mol. Res. 14(2):
2015.May.4.4
DOI:
10.4238/2015.May.4.4
Plant Genetics   Research Article

Cloning and expression analysis of cysteine protease gene (MwCP) in Agropyron mongolicum Keng

Authors: T.G.B.Y. Ao1,3, M.L. Lang2, Y.Q. Li3, Y. Zhao1, L.C. Wang1 and X.J. Yang1,2,4

In this study, a cysteine protease gene (MwCP) from Agropyron mongolicum Keng was isolated using RACE. Sequence analysis indicated that MwCP was 1473 bp, and it contained a 1134-bp open reading frame, which encoded 377 amino acids with a 24-amino acid N-terminal signal peptide. The results indicated that the MwCP protein was a new member of the papain C1A.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017424
DOI:
10.4238/gmr.15017424
Human Genetics   Research Article

Association among XRCC1, XRCC3, and BLHX gene polymorphisms and chromosome instability in lymphocytes from patients with endometriosis and ovarian cancer

Authors: M.S. Monteiro, D.B. Vilas Boas, C.B. Gigliotti and D.M.F. Salvadori

Endometriosis is a complex disease that has both benign and malignant characteristics. It affects 5-10% of women of reproductive age. Studies have demonstrated the existence of common genetic changes in endometriosis and ovarian cancer, suggesting a possible association between these 2 diseases. However, the mechanisms that le.. Read More»

Genet. Mol. Res. 13(1):
2014.January.28.9
DOI:
10.4238/2014.January.28.9