Differential microRNA expression in signet-ring cell carcinoma compared with tubular adenocarcinoma of human gastric cancer
Authors: F.Q. Li, B. Xu, Y.J. Wu Z.L. Yang and J.J. Qian
Gastric cancer is a disease with a heterogeneous pathology; its pathological mechanisms remain unclear because there is a poor understanding of its etiology. In this study, we identified differentially expressed microRNAs (miRNAs) among various gastric cancer subtypes. miRNA microarray analysis and bioinformatic analysis were used to compare miRNA expression.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.17
- DOI:
- 10.4238/2015.January.30.17
Analysis of genetic diversity of salt-tolerant alfalfa germplasms
Authors: J. Jiang, B.L. Yang, T. Xia, S.M. Yu, Y.N. Wu, H. Jin and J.R. Li
Random amplified polymorphic DNA technology was used to analyze the genetic diversity of 25 salt-tolerant alfalfa varieties using 30 different primers. Results showed that the percentage of polymorphic loci between single-plant DNA was 81.52%, and that between mixed DNA of various varieties was 61.65%. Compared to the mixed DNA samples, single-plant DNA s.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.4.1
- DOI:
- 10.4238/2015.May.4.1
Effects of 17�±-methyltestosterone on thereproduction of the freshwater snail Biomphalaria glabrata
Authors: C.L.G. Rivero-Wendt, A.C. Borges, E.C. Oliveira-Filho, A.L. Miranda-Vilela, M.F.N. Ferreiraand C.K. Grisolia
17-α-methyltestosterone (MT) is a synthetic hormone used in fish hatcheries to induce male monosex. Snails hold promise as possible test models to assess chemicals acting on the endocrine system. Biomphalaria glabrata is an aquatic gastropod mollusk (Pulmonata, Planorbidae) that can be easily maintained in aquaria, predi.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.28.6
- DOI:
- 10.4238/2014.January.28.6
Isolation and characterization of microsatellite DNA loci from the peanut worm, Sipunculus nudus
Authors: Q.H. Wang, Y.S. Guo, Z.D. Wang, X.D. Du and Y.W. Deng
Sipunculus nudus, the peanut worm, is the best known species in its genus. This unsegmented subtidal marine worm is consumed in some parts of Asia and is also used as fish bait. We found 20 microsatellite DNA markers for S. nudus. The number of alleles per polymorphic locus ranged from two to seven in a sample of 39 individual.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.June.15.15
- DOI:
- 10.4238/2012.June.15.15
Association of IL-18 polymorphisms with rheumatoid arthritis: a meta-analysis
Authors: L.L. Li1, X.F. Deng2, J.P. Li3, N. Ning1, X.L. Hou1 and J.L. Chen1
Interleukin-18 (IL-18), an important proinflammatory cytokine, has been reported to play a potential pathological role in rheumatoid arthritis (RA). Results from previous studies on the association between IL-18 polymorphisms and RA are conflicting. To clarify this, an updated meta-analysis of all available studies on IL-18 polymorphisms and RA was conduc.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017389
- DOI:
- 10.4238/gmr.15017389
Distribution of Candida albicans in the oral cavity of children aged 3-5 years of Uygur and Han nationality and their genotype in caries-active groups
Authors: N. Wu, J. Lin, L. Wu and J. Zhao
We analyzed the distribution of Candida albicans in the oral cavity of 3-5-year-old children of Uygur and Han nationalities as well as their genotypes in caries-active groups in the Urumqi municipality. CHROMagar Candida was separately cultivated, and we identified 359 Uygur and Han children aged 3-5 years. We randomly selected 20 Han children and 20 Uygur c.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.18
- DOI:
- 10.4238/2015.January.30.18
Characterization of MUSTN1 gene and its relationship with skeletal muscle development at postnatal stages in Pekin ducks
Authors: T.S. Xu, L.H. Gu, Y. Sun, X.H. Zhang, B.G. Ye, X.L. Liu and S.S. Hou
Musculoskeletal embryonic nuclear protein 1 (MUSTN1) gene is involved in myogenic fusion and differentiation in rats. We previously showed the differential expression of MUSTN1 in week (W) 2 and W6 breast muscles of Pekin ducks. In this study, we further investigated its molecular characteristics and expression profiles in different tissues at W7 and in b.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.4.2
- DOI:
- 10.4238/2015.May.4.2
Isolation of new polymorphic microsatellite markers from the marbled rockfish Sebastiscus marmoratus
Authors: H.W. Deng, Z.B. Li, G. Dai, Y. Yuan, Y.F. Ning, J.B. Shangguan and Y.S. Huang
The marbled rockfish, Sebastiscus marmoratus, is an important commercially near-shore fish that inhabits the beach rocky bottom from Japan to the South China Sea. Eleven polymorphic microsatellite loci were developed from S. marmoratus and were used to identify polymorphisms in 30 samples from a wild population. The allele locus number ranged from 2 to 7. Po.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.19
- DOI:
- 10.4238/2015.January.30.19
Analysis of the genetic diversity of super sweet corn inbred lines using SSR and SSAP markers
Authors: W.R. Ko1*, K.J. Sa1*, N.S. Roy3, H.-J. Choi2 and J.K. Lee1
In this study, we compared the efficiency of simple sequence repeat (SSR) and sequence specific amplified polymorphism (SSAP) markers for analyzing genetic diversity, genetic relationships, and population structure of 87 super sweet corn inbred lines from different origins. SSR markers showed higher average gene diversity and Shannon’s information i.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017392
- DOI:
- 10.4238/gmr.15017392
Cloning, expression analysis and sequence prediction of the CCAAT/enhancer-binding protein alpha gene of Qinchuan cattle
Authors: H. Wang, L.S. Zan, H.B. Wang, C. Gong and C.Z. Fu
CCAAT/enhancer-binding protein alpha (C/EBPα) is an essential transcription factor, regulating the differentiation of adipocytes. We cloned the complete open reading frame of C/EBPα gene of Qinchuan cattle and analyzed its protein structures and expression profile in 15 tissues via DNA cloning, sequencing and RT-PC.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.June.15.14
- DOI:
- 10.4238/2012.June.15.14