Expression and clinical significance of ADAM17 protein in esophageal squamous cell carcinoma
Authors: H.B. Liu, Y. Zhu, Q.C. Yang, Y. Shen, X.J. Zhang and H. Chen
We examined disintegrin and metalloproteinase 17 (ADAM17) protein expression in esophageal squamous cell carcinoma and its clinical and pathological correlated factors. Western blotting and immunohistochemistry were used to detect ADAM17 protein expression in esophageal squamous cell carcinoma and the corresponding normal esophageal mucosa in 50 cases. AD.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.April.30.12
- DOI:
- 10.4238/2015.April.30.12
Cytotoxicity and mutagenicity of fluoxetine hydrochloride (Prozac), with or without vitamins A and C, in plant and animal model systems
Authors: E. D�¼sman, I.V. Almeida, R.G. Mariucci, M.S. Mantovani andV.E.P. Vicentini
Fluoxetine, commonly known as Prozac, is the first representative of the so-called new generation of antidepressants that promise efficacy, with few side effects, against deep depression, nervous bulimia, and anxiety. As there is a growing number of people suffering from anxiety and depression; consequently, the use of fluoxet.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.28.3
- DOI:
- 10.4238/2014.January.28.3
Screening and identification of peritoneal metastasis-related genes of gastric adenocarcinoma using a cDNA microarray
Authors: F.H. Bai, N.J. Wang, J. Wang, L. Yang, F.M. Zhang, F. Yin, J. Liang, K.C. Wu and D.M. Fan
With the aim of identifying peritoneal metastasis-related genes in gastric cancer, we performed a broad analysis of differential gene expression between the parental cell line GC9811 and its highly metastatic peritoneal counterpart, cell line GC9811-P. Two fluorescent cDNA probes, labeled with Cy3 and Cy5 dyes, were prepared f.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.June.25.1
- DOI:
- 10.4238/2012.June.25.1
Role of fibroblast growth factor-23 in the pathogenesis of atherosclerosis in peritoneal dialysis patients
Authors: Y. Zeng, S. Feng, O.Y. Han, H.Y. Shen, D.H. Jin and Y.B. Shi
Several previous studies have demonstrated that elevated levels of fibroblast growth factor-23 (FGF-23) may be involved in atherosclerosis and contribute to the high mortality rate of peritoneal dialysis (PD) patients. The aim of this study was to determine the precise role of FGF-23 in the pathogenesis of atherosclerosis in PD patients. Between April 200.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.15
- DOI:
- 10.4238/2015.January.30.15
Body color development and genetic analysis of hybrid transparent crucian carp (Carassius auratus)
Authors: W. Xu, G.X. Tong, L.W. Geng and H.F. Jiang
The aim of this study was to investigate the genetic mechanism of the transparent trait in transparent crucian carp. We observed body color development in transparent crucian carp larvae and analyzed heredity of color in hybrids produced with red crucian carp, ornamental carp, and red purse carp. The results showed that the body color of the newly hatched.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.April.30.13
- DOI:
- 10.4238/2015.April.30.13
Expression and Localization of Luman/CREB3 in Mouse Embryos during the Pre-implantation period - Genet. Mol. Res. 14 (4): 13595-13602.
Authors: T.N. Mahmoud, P.F. Lin, F.L. Chen, J.H. Zhou, X.G. Wang, N. Wang, X. Li andY.P. Jin
In regard to the affiliation mistake that was made during our correspondence in our manuscript, we write this letter in order to correct it as per my PhD requirements and this is the Final decision as I have no other option. The correction is only in the affiliation and should be: T.N. Mahmoud1,2, P.F. Lin1, F.L. Chen1, J.H. Zhou1, X.G. Wang1, N. Wang1, X.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.150156091
- DOI:
- 10.4238/gmr.150156091
Does beekeeping reduce genetic variability in Melipona scutellaris (Apidae, Meliponini)?
Authors: G.A. Carvalho-Zilse, M.F.F. Costa-Pinto, C.G. Nunes-Silva, W.E. Kerr
Many factors have contributed to reductions in wild populations of stingless bees, such as: deforestation, displacement and destruction of nests by honey gatherers, as well as use of insecticides and other agrochemicals. All of these can potentially affect the populational structure of native species. We analyzed genetic varia.. Read More»
- Genet. Mol. Res. 8(2):
- vol8-2keer006
- DOI:
- 10.4238/vol8-2keer006
Association between a functional single nucleotide polymorphism in the brain-derived neurotrophic factor gene and risk of child asthma
Authors: J.Y. Wang, A.L. Wang, W. Han, Z.L. Mu
Brain-derived neurotrophic factor (BDNF) promotes synaptic remodeling and modulates the function of other neurotransmitters. Allergic inflammation triggers neuronal dysfunction and structural changes in the airways. Genetic polymorphisms in functional regions of the BDNF gene have a plausible role in modulating the risk of chi.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.8.13
- DOI:
- 10.4238/2015.December.8.13
Ovine prion protein genotype frequencies in northwestern China
Authors: C.-L. Zhao, R. Wu, L. Liu, F.-D. Li, X.-L. Zhang, C. Wang, F. Wang, X.-L. Diao, H.-W. Guan, X. Wang and L. Zhou
Anti-scrapie breeding programs have been initiated to screen for scrapie-resistant sheep based on ovine prion protein gene (PRNP) genotypes at codons 136, 154 and 171 in many countries, especially European Union member states. However, investigation of sheep PRNP genotypes is limited in China, despite the large number of sheep.. Read More»
- Genet. Mol. Res. 11(2):
- dx.doi.org/2012.June.21.2
- DOI:
- dx.doi.org/10.4238/2012.June.21.2
MKL1-184C>T gene polymorphism is associated with coronary artery diseasein the Chinese Han population
Authors: Y. Xu B. Li, Y.-Z. Bao, X.-Y. Zhang, Z.-Y. Zhu, X.-F. Zhao,Y.-N. Shi, D. Li, S.-H. Chen, Y. Guo and C.-H. Cui
We investigated genetic susceptibility to coronary artery disease (CAD) by studying the association of MKL1 gene polymorphisms with CAD in the Chinese Han population. We performed a case-control study with 476 unrelated CAD patients and 325 non-CAD controls. All SNPs were genotyped with a TaqMan SNP genotyping assay. The distr.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.28.4
- DOI:
- 10.4238/2014.January.28.4