Association of the GSTT1 polymorphism in upper aerodigestive tract cancer with tobacco smoking
Authors: T.M. Silva, C.R. Marques, M.F. Marques Filho, A.B. Marques,G. Di Pietro and F. Rios-Santos
Polymorphisms in genes encoding xenobiotic-metaboli- zing enzymes might explain differences in the susceptibility to upper aerodigestive tract (UADT) cancers in individuals exposed to tobacco or other carcinogens. The present study aimed to evaluate the association of polymorphisms in the glutathione S-transferase (GST) candid.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.21.22
- DOI:
- 10.4238/2014.January.21.22
Selection of cowpea progenies with enhanced drought-tolerance traits using principal component analysis
Authors: C.C. Sousa,K.J. Damasceno-Silva, E.A. Bastos,M.M. Rocha
Vigna unguiculata (L.) Walp (cowpea) is a food crop with high nutritional value that is cultivated throughout tropical and subtropical regions of the world. The main constraint on high productivity of cowpea is water deficit, caused by the long periods of drought that occur in these regions. The aim of the present study was to.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.10
- DOI:
- 10.4238/2015.December.7.10
Optimization of DNA extraction from fresh leaf tissues of Melanoxylon brauna (Fabaceae)
Authors: D.B. Borges, M.B. Amorim, A.M. Waldschmidt, E. Mariano-Neto, C.V. Vivas and D.G. Pereira
Melanoxylon brauna (Fabaceae - Caesalpinioideae) is an endemic and valuable hardwood tree species in the Brazilian Atlantic rainforest; it is comparable to African ebony wood. We tested three protocols of DNA extraction based on the citrimonium bromide (CTAB) method and evaluated the quantity, purity and integrity of the DNA. .. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.22.8
- DOI:
- 10.4238/2012.May.22.8
Study on serum proteomic features in patients with and without recurrence or metastasis after surgical resection of esophageal carcinoma
Authors: G.B. Zheng, C.F. Gao, X.L. Wang, G. Zhao and D.H. Li
The purpose of this study was to identify specific biomarkers for recurrence or metastasis of esophageal carcinoma in serum of patients subjected to esophagectomy. Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS) combined with IMAC-Cu2+ ProteinChip array were performed for the serum .. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.21.23
- DOI:
- 10.4238/2014.January.21.23
Role of VEGF gene polymorphisms in the clinical outcome of non-small cell lung cancer
Authors: N. Chen, C.N. Ma, M. Zhao, Y.J. Zhang
This report details a study conducted to assess the role of VEGF gene polymorphisms in the prognosis of advanced non-small cell lung carcinoma (NSCLC). Samples obtained from 210 advanced NSCLC patients admitted at the Huaihe Hospital of Henan University between January 2010 and December 2011 were recruited for this study. The .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.13
- DOI:
- 10.4238/2015.December.7.13
Determination of SCN1A genetic variants in Mexican patients with refractory epilepsy and Dravet syndrome
Authors: R.E. Jim�©nez-Arredondo, A.J.L. Brambila-Tapia, F.M. Mercado-Silva, M.T. Maga�±a-Torres and L.E. Figuera
Mutations in the SCN1A gene can result in syndromes associated with epilepsy, including the Dravet syndrome (DS). However, the prevalence of such mutations in these diseases varies widely between different studies, and has not been examined in Mexican patients with epilepsy. Therefore, the objective of this study was to determ.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029405
- DOI:
- 10.4238/gmr16029405
Diversity of endophytic fungal community associated with Piper hispidum (Piperaceae) leaves
Authors: R.C. Orlandelli, R.N. Alberto, C.J. Rubin Filho and J.A. Pamphile
Tropical and subtropical plants are rich in endophytic community diversity. Endophytes, mainly fungi and bacteria, inhabit the healthy plant tissues without causing any damage to the hosts. These fungi can be useful for biological control of pathogens and plant growth promotion. Some plants of the genus Piper are hosts of endophytic microorganisms; howeve.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.22.7
- DOI:
- 10.4238/2012.May.22.7
Temporal and spatial expression profiles of Frizzled 3 in the ovary during the estrous cycle
Authors: S.B. Wang1,2,3, Y.P. Liu1,2, Z.H. Zhang2, Z.K. Wang2,3, Y.X. Xu3 and Z.C. Wang1,2,3
Frizzled 3 is an important receptor in the Wnt/β-catenin pathway, a conserved signaling pathway that regulates gene expression and controls diverse developmental processes. However, the role of this protein during follicular development in the adult ovary is not known. The present study was designed to investigate the expression and localization of F.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017152
- DOI:
- 10.4238/gmr.15017152
Genome-wide identification and evolutionary analysis of nucleotide-binding site-encoding resistance genes in Lotus japonicus (Fabaceae)
Authors: H. Song, P.F. Wang,T.T. Li, H. Xia,S.Z. Zhao, L. Hou,C.Z. Zhao
Nucleotide-binding site (NBS) disease resistance genes play a crucial role in plant defense responses against pathogens and insect pests. Many NBS-encoding genes have been detected in Lotus japonicus, an important forage crop in many parts of the world. However, most NBS genes identified so far in L. japonicus were only partia.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.16
- DOI:
- 10.4238/2015.December.7.16
New microsatellite loci for the mandarin fish Siniperca chuatsi and their application in population genetic analysis
Authors: C.X. Tian, X.-F. Liang, M. Yang, Y.Q. Dou, H.Z. Zheng, L. Cao,Y.C. Yuan and C. Zhao
The mandarin fish is a popular fresh water food fish in China. Fifty-three polymorphic microsatellite markers were isolated through construction of an enriched library of genomic DNA of Siniperca chuatsi (Percichthyidae). We found 2 to 7 alleles per locus. The observed and expected heterozygosity values varied from 0.059 to 1... Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.22.1
- DOI:
- 10.4238/2014.January.22.1