Predicted philogeny, secondary conformational structure, and epitope antigenicity of immunological sequences in poultry
Authors: L.J. Lara, A.P. Peconick, ��.J. Fassani, A.M.P. J�ºnior, P.R.B. Chalfun, D.L. Raymundo, T.A. Bar�§ante and J.M. de P. Bar�§ante
Poultry production is faced with different types of stresses that are responsible for issues of animal welfare as well as for economic losses. Moreover, the immunity decreases when animals are stressed. In silico analyses are important in reducing the cost and in increasing the accuracy of scientific results. A bioinformatics .. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029423
- DOI:
- 10.4238/gmr16029423
Significant association between the MTHFR A1298C polymorphism and hepatocellular carcinoma risk: a meta-analysis
Authors: W. Chang, Q. Meng, J.H. Liu, L.X. Wu, Y. Chen,S.D. Chen
The A1298C polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene has been reported to be associated with hepatocellular carcinoma (HCC), but there are conflicting results from previous studies. The present study aimed to investigate the association between this polymorphism and the risk of HCC using a meta-analy.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.9
- DOI:
- 10.4238/2015.December.7.9
LAMP-PCR detection of ochratoxigenic Aspergillus species collected from peanut kernel
Authors: H.M. Al-Sheikh
Over the last decade, ochratoxin A (OTA) has been widely described and is ubiquitous in several agricultural products. Ochratoxins represent the second-most important mycotoxin group after aflatoxins. A total of 34 samples were surveyed from 3 locations, including Mecca, Madina, and Riyadh, Saudi Arabia, during 2012. Fungal contamination frequency was det.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.5
- DOI:
- 10.4238/2015.January.30.5
Associations between HLA-A\B\DRB1 polymorphisms and risks of vulvar lichen sclerosus or squamous cell hyperplasia of the vulva
Authors: G.L. Liu,F.L. Cao, M.Y. Zhao,J. Shi, S.H. Liu
In this study, we aimed to explore the associations between HLA-A\B\DRB1 polymorphisms and the risks of vulvar lichen sclerosus (VLS) or squamous cell hyperplasia of the vulva (SCHV) in Han Chinese women. We enrolled 76 Han Chinese women with VLS (Group A), 74 with SCHV (Group B), and 66 healthy women (control group) in this s.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.8
- DOI:
- 10.4238/2015.December.7.8
Correlation analysis between the delayed rectifier potassium channel KCNE1 (G38S) polymorphism and atrial fibrillation among the senior Uygur population in Xinjiang
Authors: N. Wugeti, G. Yu-Jun, S. Juan, A. Mahemuti
Current resources to support genetic screening among the Uygur population in Xinjiang territory for atrial fibrillation (AF) have not been well established and large-scale epidemiological analyses are needed. Using patients from the Xinjiang Uygur population as subjects, and the delayed rectifier potassium channel KCNE1 and it.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.4
- DOI:
- 10.4238/2015.December.7.4
Milk yield persistency in Brazilian Gyr cattle based on a random regression model
Authors: R.J. Pereira, R.S. Verneque, P.S. Lopes, M.L. Santana Jr., M.R. Lagrotta, R.A. Torres, A.E. Vercesi Filho, M.A. Machado
With the objective of evaluating measures of milk yield persistency, 27,000 test-day milk yield records from 3362 first lactations of Brazilian Gyr cows that calved between 1990 and 2007 were analyzed with a random regression model. Random, additive genetic and permanent environmental effects were modeled using Legendre polyno.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.June.15.9
- DOI:
- 10.4238/2012.June.15.9
Genetic gains in the UENF-14 popcorn population with recurrent selection
Authors: I.L.J. Freitas, A.T. do Amaral J�ºnior, S.P. Freitas Jr., P.D.S. Cabral, R.M. Ribeiro and L.S.A. Gon�§alves
The popcorn breeding program of Universidade Estadual do Norte Fluminense Darcy Ribeiro aims to provide farmers a cultivar with desirable agronomic traits, particularly with respect to grain yield (GY) and popping expansion (PE). We evaluated full-sib families from the seventh cycle of recurrent selection and estimated the gen.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.21.21
- DOI:
- 10.4238/2014.January.21.21
Changes of circulating CD4+CD25+CD127low regulatory T cells in patients with acute coronary syndrome and its significance
Authors: M. Liu, L.-J. Xu, J.-X. Wu
The aim of this study was to investigate the changes of circulating CD4+CD25+CD127low regulatory T cells (Treg) in patients with acute coronary syndrome (ACS) and its significance. The experiment was divided into three groups: ACS (48 patients), stable angina pectoris (SAP) (24 patients), and normal controls (24 subjects). The.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.4
- DOI:
- 10.4238/2015.December.7.4
Inhibition of andrographolide in RAW 264.7 murine macrophage osteoclastogenesis by downregulating the nuclear factor-kappaB signaling pathway
Authors: Y.Q. Ren,Y.B. Zhou
This study aims to investigate the effects of andrographolide (AGP) on osteoclast formation in RAW 264.7 murine macrophage cells. The effects of AGP on cell viability were determined in RAW 264.7 cells using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The effects of AGP on osteoclast formation.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.7
- DOI:
- 10.4238/2015.December.7.7
SLC30A8 (ZnT8) variations and type 2 diabetes in the Chinese Han population
Authors: J. Xu, J. Wang and B. Chen
In recent genome-wide association studies, variants in the SLC30A8 gene have been found to be associated with risk for type 2 diabetes. We examined a possible association of tag SNPs spanning SLC30A8 and their haplotypes with type 2 diabetes in the Chinese Han population. There were 1508 Chinese Han type 2 diabetes patients an.. Read More»
- Genet. Mol. Res. 11(2):
- dx.doi.org/2012.May.24.1
- DOI:
- dx.doi.org/10.4238/2012.May.24.1